Developing Multimodal Therapies For Brain Disorders
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| Author | : National Academies of Sciences, Engineering, and Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 97 |
| Release | : 2017-03-13 |
| Genre | : Medical |
| ISBN | : 0309450268 |
Multimodal therapy approaches that combine interventions aimed at different aspects of disease are emerging as potentialâ€"and perhaps essentialâ€"ways to enhance clinical outcomes for patients with psychiatric and neurological disorders. In order to examine the general principles underlying multimodal therapies and to explore challenges, potential barriers, and opportunities for their development, the National Academies of Sciences, Engineering, and Medicine convened a workshop in June 2016. Participants explored scientific, clinical, regulatory, and reimbursement issues related to multimodal approaches and potential opportunities to enhance clinical outcomes for individuals with nervous system disorders. This publication summarizes the presentations and discussions from the workshop.
| Author | : Gary J. Ockey |
| Publisher | : Springer Nature |
| Total Pages | : 268 |
| Release | : 2020-11-23 |
| Genre | : Education |
| ISBN | : 9811589526 |
This edited book is a collection of papers, written by language assessment professionals to reflect the guidance of Professor Lyle F. Bachman, one of the leading second language assessment experts in the field for decades. It has three sub-themes: assessment of evolving language ability constructs, validity and validation of language assessments, and understanding internal structures of language assessments. It provides theoretical guidelines for practical language assessment challenges. Chapters are written by language assessment researchers who graduated from the University of California, Los Angeles, where Professor Bachman trained them including the book editors.
| Author | : |
| Publisher | : Academic Press |
| Total Pages | : 684 |
| Release | : 2016-10-06 |
| Genre | : Medical |
| ISBN | : 0128018496 |
Functional Neurologic Disorders, the latest volume in the Handbook of Clinical Neurology series, summarizes state-of-the-art research findings and clinical practice on this class of disorders at the interface between neurology and psychiatry. This 51-chapter volume offers an historical introduction, chapters on epidemiology and pathophysiolology, a large section on the clinical features of different type of functional neurologic symptoms and disorders (including functional movement disorders, non-epileptic seizures, dizziness, vision, hearing, speech and cognitive symptoms), and then concluding with approaches to therapy. This group of internationally acclaimed experts in neurology, psychiatry, and neuroscience represent a broad spectrum of areas of expertise, chosen for their ability to write clearly and concisely with an eye toward a clinical audience. This HCN volume sets a new landmark standard for a comprehensive, multi-authored work dealing with functional neurologic disorders (also described as psychogenic, dissociative or conversion disorders). - Offers a comprehensive interdisciplinary approach for the care of patients with functional disorders seen in neurologic practice, leading to more efficient prevention, management, and treatment - Provides a synthesis of research efforts incorporating clinical, brain imaging and neurophysiological studies - Fills an existing gap between traditional neurology and traditional psychiatry - Contents include coverage of history, epidemiology, clinical presentations, and therapy - Edited work with chapters authored by leaders in the field, the broadest, most expert coverage available
| Author | : António Salgado |
| Publisher | : Elsevier |
| Total Pages | : 712 |
| Release | : 2020-06-10 |
| Genre | : Medical |
| ISBN | : 0128180854 |
Handbook of Innovations in CNS Regenerative Medicine provides a comprehensive overview of the CNS regenerative medicine field. The book describes the basic biology and anatomy of the CNS and how injury and disease affect its balance and the limitations of the present therapies used in the clinics. It also introduces recent trends in different fields of CNS regenerative medicine, including cell transplantation, bio and neuro-engineering, molecular/pharmacotherapy therapies and enabling technologies. Finally, the book presents successful cases of translation of basic research to first-in-human trials and the steps needed to follow this path. Areas such as cell transplantation approaches, bio and neuro-engineering, molecular/pharmacotherapy therapies and enabling technologies are key in regenerative medicine are covered in the book, along with regulatory and ethical issues. - Describes the basic biology and anatomy of the CNS and how injury and disease affect its balance - Discusses the limitations of present therapies used in the clinics - Introduces the recent trends in different fields of CNS regenerative medicine, including cell transplantation, bio and neuro-engineering, molecular/pharmacotherapy therapies, and enabling technologies - Presents successful cases of translation of basic research to first-in-human trials, along with the steps needed to follow this path
| Author | : Michael R. Hamblin |
| Publisher | : Academic Press |
| Total Pages | : 658 |
| Release | : 2019-07-13 |
| Genre | : Medical |
| ISBN | : 0128153067 |
Photobiomodulation in the Brain: Low-Level Laser (Light) Therapy in Neurology and Neuroscience presents the fundamentals of photobiomodulation and the diversity of applications in which light can be implemented in the brain. It will serve as a reference for future research in the area, providing the basic foundations readers need to understand photobiomodulation's science-based evidence, practical applications and related adaptations to specific therapeutic interventions. The book covers the mechanisms of action of photobiomodulation to the brain, and includes chapters describing the pre-clinical studies and clinical trials that have been undertaken for diverse brain disorders, including traumatic events, degenerative diseases and psychiatric disorders. - Provides a much-needed reference on photobiomodulation with an unprecedented focus on the brain and its disorders - Features a body of world-renowned editors and chapter authors that promote research, policy and funding - Discusses the recent and rapid accumulation of literature in this area of research and the shift towards the use of non-invasive techniques in therapy
| Author | : National Academies of Sciences, Engineering, and Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 483 |
| Release | : 2017-09-28 |
| Genre | : Medical |
| ISBN | : 0309459575 |
Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.
| Author | : Elizabeth B. Torres |
| Publisher | : Academic Press |
| Total Pages | : 580 |
| Release | : 2018-06-29 |
| Genre | : Medical |
| ISBN | : 0128041188 |
Objective Biometric Methods for the Diagnosis and Treatment of Nervous System Disorders provides a new and unifying methodological framework, introducing new objective biometrics to characterize patterns of sensory motor control underlying symptoms. Its goal is to radically transform the ways in which disorders of the nervous system are currently diagnosed, tracked, researched and treated. This book introduces new ways to bring the laboratory to the clinical setting, to schools and to settings of occupational and physical therapy. Ready-to-use, graphic user interfaces are introduced to provide outcome measures from wearable sensors that automatically assess in near real time the effectiveness of interventions. Lastly, examples of how the new framework has been effectively utilized in the context of clinical trials are provided. - Provides methods and their implementation using real data and simple computer programs that students and researchers from less technically trained fields can use - Describes the motivation for methods according to the problem domain in light of existing methods for each chapter, along with their lack of neuroscientific foundation and invalid statistical assumptions - Accompanied by a companion website which contains Appendices with MATLAB codes and data samples to generate the graphics displayed in all chapter figures - Features videos illustrating the experimental set up for scenarios and methods described in each chapter - Includes step-by-step explanations of paradigms in each clinical or typical sample population to enable reproducibility of the study across different clinical phenotypes and levels of expertise in sports, the performing arts, or mere individual academic predispositions/preferences
| Author | : Michelle Hampson |
| Publisher | : Academic Press |
| Total Pages | : 366 |
| Release | : 2021-10-09 |
| Genre | : Computers |
| ISBN | : 0128224363 |
fMRI Neurofeedback provides a perspective on how the field of functional magnetic resonance imaging (fMRI) neurofeedback has evolved, an introduction to state-of-the-art methods used for fMRI neurofeedback, a review of published neuroscientific and clinical applications, and a discussion of relevant ethical considerations. It gives a view of the ongoing research challenges throughout and provides guidance for researchers new to the field on the practical implementation and design of fMRI neurofeedback protocols. This book is designed to be accessible to all scientists and clinicians interested in conducting fMRI neurofeedback research, addressing the variety of different knowledge gaps that readers may have given their varied backgrounds and avoiding field-specific jargon. The book, therefore, will be suitable for engineers, computer scientists, neuroscientists, psychologists, and physicians working in fMRI neurofeedback. - Provides a reference on fMRI neurofeedback covering history, methods, mechanisms, clinical applications, and basic research, as well as ethical considerations - Offers contributions from international experts—leading research groups are represented, including from Europe, Japan, Israel, and the United States - Includes coverage of data analytic methods, study design, neuroscience mechanisms, and clinical considerations - Presents a perspective on future translational development
| Author | : Mark Hallett |
| Publisher | : Lippincott Williams & Wilkins |
| Total Pages | : 388 |
| Release | : 2006 |
| Genre | : Medical |
| ISBN | : 9780781796279 |
This groundbreaking volume is the first text devoted to psychogenic movement disorders. Co-published by Lippincott Williams & Wilkins and the American Academy of Neurology, the book contains the highlights of an international, multidisciplinary conference on these disorders and features contributions from leading neurologists, psychiatrists, psychologists, physiatrists, and basic scientists. Major sections discuss the phenomenology of psychogenic movement disorders from both the neurologist's and the psychiatrist's viewpoint. Subsequent sections examine recent findings on pathophysiology and describe current diagnostic techniques and therapies. Also included are abstracts of 16 seminal free communications presented at the conference.
| Author | : Lily Trokenberg Hechtman |
| Publisher | : Oxford University Press |
| Total Pages | : 329 |
| Release | : 2017 |
| Genre | : Medical |
| ISBN | : 0190213582 |
Comprehensive description of adult outcome in educational, occupational, emotional, social, substance use, legal, antisocial functioning is described via the best well-controlled prospective follow-up studies of children with ADHD into adulthood. Predictors of outcome, e.g., medication and psychosocial treatment, IQ, severity of ADHD, comorbidity, SES, parental pathology and family functioning are all explored. Prognosis and issues that need to be addressed to promote more positive outcome are thus addressed.
