Dendrimers In Medicine
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| Author | : U Boas |
| Publisher | : Royal Society of Chemistry |
| Total Pages | : 191 |
| Release | : 2007-10-31 |
| Genre | : Science |
| ISBN | : 1847552676 |
Dendrimers are a new class of macromolecule increasingly used in the fields of synthetic organic chemistry, biology, medicine and biotechnology. Dendrimers in Medicine and Biotechnology: New Molecular Tools looks at this exciting and rapidly growing area of science. Using an interdisciplinary approach with particular emphasis on biological applications, the book discusses the relationship between the dendrimer molecular motif and its biological properties. A general introduction to the subject of dendrimers, including definitions of terms and symbols, is provided. Subsequent sections discuss topics including dendrimers in biological systems, dendrimers as drug delivery devices, dendrimers in diagnostics and dendrimer drugs. Throughout the book examples from current research are also provided. This book will appeal to a wide range of scientists, including non specialists who require an introduction to dendrimers, as well as those wishing to know more about the application of dendrimers in the field of biology and medicine.
| Author | : Prashant Kesharwani |
| Publisher | : Academic Press |
| Total Pages | : 486 |
| Release | : 2021-04-14 |
| Genre | : Medical |
| ISBN | : 0128212519 |
Dendrimer-Based Nanotherapeutics delivers a comprehensive resource on the use of dendrimer-based drug delivery. Advances in the application of nanotechnology in medicine have given rise to multifunctional smart nanocarriers that can be engineered with tunable physicochemical characteristics to deliver one or more therapeutic agent(s) safely and selectively to cancer cells, including intracellular organelle-specific targeting. This book compiles the contribution of dendrimers in the field of nanotechnology to aid researchers in exploring dendrimers in the field of drug delivery and related applications. This book covers the history of the area to the most recent research. The starting chapter covers detailed information about basic properties about dendrimers i.e. properties, nomenclature, synthesis methods, types, characterization of dendrimers, safety and toxicity issues of dendrimers. Further chapters discuss the most recent advancements in the field of dendrimer i.e. dendrimer-drug conjugates, PEGylated dendrimer, dendrimer surface engineering, dendrimer hybrids, dendrimers as solubility enhancement, in targeting and delivery of drugs, as photodynamic therapy, in tissue engineering, as imaging contrast agents, as antimicrobial agents, advances in targeted dendrimers for cancer therapy and future considerations of dendrimers. Dendrimer-Based Nanotherapeutics will help the readers to understand the most recent progress in the field of dendrimer-based research, suitable for pharmaceutical scientists, advanced students, and those working in related healthcare fields. - Discusses various routes such as oral, pulmonary, transdermal, delivery and local administration of dendrimer delivery of bioactive - Explores a wide range of applications of dendrimer-based drug delivery using the latest advancements in nanomedicine - Provides the most recent research on dendrimers as well as context and background, providing a useful resource for all levels of researcher
| Author | : Anil K. Sharma |
| Publisher | : CRC Press |
| Total Pages | : 406 |
| Release | : 2018-07-27 |
| Genre | : Medical |
| ISBN | : 135136068X |
With chapters from highly skilled, experienced, and renowned scientists and researchers from around the globe, Dendrimers for Drug Delivery provides an abundance of information on dendrimers and their applications in the field of drug delivery. The volume begins with an introduction to dendrimers, summarizing dendrimer applications and the striking features of dendrimers. It goes on to present the details of usual properties, structure, classification, and methods of synthesis, with relevant examples. The toxicity of dendrimers is also discussed. The chapter authors provide an exhaustive amount of information about dendrimers and their biomedical applications, including biocompatibility and toxicity aspects, a very useful feature. This informative volume will be valuable resource that will help readers to create products derived from dendrimers and navigate through the regulatory, manufacturing, and quality control hurdles. It will be an important resource for researchers, scientists, upper-level students, and industry professionals.
| Author | : Ecaterina Andronescu |
| Publisher | : Elsevier |
| Total Pages | : 1036 |
| Release | : 2017-04-11 |
| Genre | : Business & Economics |
| ISBN | : 0323477216 |
Nanostructures for Oral Medicine presents an up-to-date examination of the applications and effects of nanostructured materials in oral medicine, with each chapter addressing recent developments, specific applications, and uses of nanostructures in the oral administration of therapeutic agents in dentistry. The book also includes coverage of the biocompatibility of nanobiomaterials and their remarkable potential in improving human health and in reducing environmental pollution. Emerging advances, such as Dr. Franklin Tay's concept of a new nanotechnology process of growing extremely small, mineral-rich crystals and guiding them into the demineralized gaps between collagen fibers to prevent the aging and degradation of resin-dentin bonding is also discussed. This work will be of great value to those who work in oral medicine, providing them with a resource to gain a greater understanding of how nanotechnology can help them create more efficient, cost-effective products. In addition, it will be of great interest to those who work in materials science who wish to gain a greater appreciation of how nanostructured materials are applied in this field. - Outlines the major uses of nanostructured materials for oral medicine, including the properties of each material discussed and how it should best be applied - Explores how nanostructured materials enable the creation of more effective drug delivery systems in oral medicine - Discusses how novel uses of nanostructured materials may be applied in oral medicine to create more effective devices
| Author | : Neelesh Kumar Mehra |
| Publisher | : CRC Press |
| Total Pages | : 401 |
| Release | : 2021-03-24 |
| Genre | : Science |
| ISBN | : 1000333175 |
Dendrimers, hyperbranched macromolecules, emerged just few decades ago but show promising potential as drug delivery nanocarriers, theranostic agents and gene vectors; in the pharmaceutical research and innovation area as well as in other healthcare applications. Although tremendous advancements have been made in dendrimer chemistry and their applications since their emergence, the synthesis, development and design of pure and safe dendrimer-based products have been a major challenge in this area. This book, edited by well-known researchers in the area of nanomaterials and drug-based drug delivery applications, exhaustively covers the nanotechnological aspects, concepts, properties, characterisation, application, biofate and regulatory aspects of dendrimers. It includes sixteen vivid chapters by renowned formulators, researchers and academicians from all over the world, highlighting their specialised areas of interest in the fields of chemistry, biology, pharmacy and nanomedicine. Features: • Highlights dendrimers’ advancements in nanomedicine in the development of safe healthcare and biotechnological products • Covers physicochemical aspects, biofate, drug delivery aspects and gene therapy using dendrimers • Covers biomedical application of dendrimers in the field of biological sciences • Gives examples of dendrimer–guest interaction chemistry Dendrimers in Nanomedicine: Concept, Theory and Regulatory Perspectives provides the comprehensive overview of the latest research efforts in designing, optimising, development and scale-up of dendrimer-mediated delivery systems. It analyses the key challenges of synthesis, design, molecular modelling, fundamental concepts, drug delivery aspects, analytical tools and biological fate as well as regulatory consideration to the practical use of dendrimer application. Dr. Neelesh Kumar Mehra Assistant Professor of Pharmaceutics in the Department of Pharmaceutics at the National Institute of Pharmaceutical Education & Research (NIPER), Hyderabad, India. He has authored more than sixty peer-reviewed publications in highly reputed international journals, as well as book chapters and contributions on two patents. Dr. Mehra has 11 years of rich research and teaching experience in the formulation and development of complex, innovative biopharmaceutical products including micro- and nanotechnologies for regulated markets. Dr. Keerti Jain Assistant Professor of Pharmaceutics in the Department of Pharmaceutics, NIPER, Raebareli, India. For more than 10 years, she has been actively engaged in formulation and development of nanomedicines. Dr. Jain has supervised masters and doctoral pharmaceutics students in their research works which have been published in high quality, good impact factor journals. She has also authored more than 60 international manuscripts in peer reviewed high impact journals. In 2019, she was awarded the prestigious ICMR-Amir Shakuntala Award.
| Author | : Vijay Mishra |
| Publisher | : Academic Press |
| Total Pages | : 553 |
| Release | : 2017-05-23 |
| Genre | : Medical |
| ISBN | : 0128097183 |
Nanotechnology-Based Approaches for Targeting and Delivery of Drugs and Genes provides an overview of the important aspects of nanomedicine in order to illustrate how to design and develop novel and effective drug delivery systems using nanotechnology. The book is organized into three sections, beginning with an introduction to nanomedicine and its associated issues. Section two discusses the latest technologies in nanomedicine, while the third section covers future developments and challenges in the field. By focusing on the design, synthesis, and application of a variety of nanocarriers in drug and gene delivery, this book provides pharmaceutical and materials science students, professors, clinical researchers, and industry scientists with a valuable resource aimed at tackling the challenges of delivering drugs and genes in a more targeted manner. - Explores a wide range of promising approaches for the diagnosis and treatment of diseases using the latest advances in cutting-edge nanomedical technologies - Contains contributions from world-renowned experts and researchers working in the area of nanomedicine and drug delivery - Covers the associated challenges and potential solutions to working with nanotechnology in drug delivery - Highlights crucial topics, such as biopharmaceutical and toxicity issues, quality by design, drug targeting, and more
| Author | : Istvan Majoros |
| Publisher | : Pan Stanford Publishing |
| Total Pages | : 434 |
| Release | : 2008-05-31 |
| Genre | : Medical |
| ISBN | : 9814241040 |
A compilation of cutting-edge research in science and medicine from the interdisciplinary team of the Michigan Nanotechnology Institute for Medicine and Biological Sciences, this book details the applications of dendrimers in medicine. Edited by Istvan J. Majoros and James R. Baker Jr, two prominent nanotechnology researchers, this book will appeal to anyone involved in nanotechnology, macromolecular science, cancer therapy or drug delivery research.
| Author | : Sougata Jana |
| Publisher | : Woodhead Publishing |
| Total Pages | : 424 |
| Release | : 2017-06-15 |
| Genre | : Technology & Engineering |
| ISBN | : 0081019157 |
Biopolymer-Based Composites: Drug Delivery and Biomedical Applications presents a comprehensive review on recent developments in biopolymer-based composites and their use in drug delivery and biomedical applications. The information contained in this book is critical for the more efficient use of composites, as detailed up-to-date information is a pre-requirement. The information provided brings cutting-edge developments to the attention of young investigators to encourage further advances in the field of bio-composite research. Currently, biopolymers are being investigated for the design of various drug delivery and biomedical devices due to their non-toxic, biodegradable and biocompatible nature. Mostly, biopolymer-based solid orals, gels, hydrogel beads, and transdermal matrices have been designed in order to control drug/protein release in simulated bio-fluids. - Presents the most updated information in the field of pharmaceutical and biological sciences - Contains color figures and illustrations to help users understand key topics - Useful guide for young researchers working towards new innovations - Includes chapters covered by eminent scientists in the field
| Author | : Sougata Jana |
| Publisher | : John Wiley & Sons |
| Total Pages | : 1063 |
| Release | : 2022-04-18 |
| Genre | : Science |
| ISBN | : 3527349049 |
A comprehensive discussion of various types of nanoengineered biomaterials and their applications In Nanoengineering of Biomaterials: Drug Delivery & Biomedical Applications, an expert team of chemists delivers a succinct exploration of the synthesis, characterization, in-vitro and in-vivo drug molecule release, pharmacokinetic activity, pharmacodynamic activity, and the biomedical applications of several types of nanoengineered biomaterials. The editors have also included resources to highlight the most current developments in the field. The book is a collection of valuable and accessible reference sources for researchers in materials chemistry and related disciplines. It uses a functions-directed approach to using organic and inorganic source compounds that translate into biological systems as scaffolds, micelles, dendrimers, and other delivery systems. Nanoengineering of Biomaterials offers readers up-to-date chemistry and material science insights that are readily transferrable to biomedical systems. The book also includes: Thorough introductions to alginate nanoparticle delivery of therapeutics and chitosan-based nanomaterials in biological applications Comprehensive explorations of nanostructured carrageenan as a drug carrier, gellan gum nanoparticles in drug delivery, and guar-gum nanoparticles in the delivery of bioactive molecules Practical discussions of protein-based nanoparticles for drug delivery, solid lipid nanoparticles as drug carriers, and pH-responsive nanoparticles in therapy In-depth examinations of stimuli-responsive nano carriers in drug targeting Perfect for pharmaceutical chemists, materials scientists, polymer chemists, life scientists, and medicinal chemists, Nanoengineering of Biomaterials: Drug Delivery and Biomedical Applications is also an indispensable resource for biologists and bioengineers seeking a one-stop reference on the transferability of materials chemistry and nanotechnology to biomedicine.
| Author | : Delphine Felder-Flesch |
| Publisher | : CRC Press |
| Total Pages | : 424 |
| Release | : 2016-10-26 |
| Genre | : Medical |
| ISBN | : 9814745502 |
Nanomedicine can take advantage of the recent developments in nanobiotechnology research for the creation of platforms with superior drug carrier capabilities, selective responsiveness to the environment, unique contrast enhancement profiles, and improved accumulation at the disease site. This book provides a broad glimpse of how various dendritic nanomaterials have been designed and used as efficient tools for nanomedicine. It comprises a pedagogic introduction to dendrimers and hyperbranched systems and their classical and accelerated syntheses through cutting-edge methodologies. The chapters on dendronized magnetic nanoparticles as theranostics, dendrimers in theory (molecular simulations), siRNA delivery with dendrimers, and dendrimers for image-guided therapy, combined with chapters focused on specific types of dendrimers or hyperbranched structures, detail the cutting-edge research in nanomedicine. Finally, a detailed chapter on issues related to the pharmacokinetics and biodistribution of dendrimers helps choose the right structures for successful transfer from bench to bedside. This book will appeal to those involved in nanobiotechnology, macromolecular science, cancer therapy, tissue repair, and siRNA delivery research.
