Crosstalk And Integration Of Membrane Trafficking Pathways
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Author | : Roberto Weigert |
Publisher | : BoD – Books on Demand |
Total Pages | : 262 |
Release | : 2012-04-11 |
Genre | : Science |
ISBN | : 9535105159 |
Membrane traffic is a broad field that studies the complex exchange of membranes that occurs inside the cell. Protein, lipids and other molecules traffic among intracellular organelles, and are delivered to, or transported from the cell surface by virtue of membranous carriers generally referred as "transport intermediates". These carriers have different shapes and sizes, and their biogenesis, modality of transport, and delivery to the final destination are regulated by a multitude of very complex molecular machineries. A concept that has clearly emerged in the last decade is that each membrane pathway does not represent a close system, but is fully integrated with all the other trafficking pathways. The aim of this book is to provide a general overview of the extent of this crosstalk.
Author | : Roberto Weigert |
Publisher | : |
Total Pages | : 260 |
Release | : 2012 |
Genre | : |
ISBN | : 9789535152729 |
Membrane traffic is a broad field that studies the complex exchange of membranes that occurs inside the cell. Protein, lipids and other molecules traffic among intracellular organelles, and are delivered to, or transported from the cell surface by virtue of membranous carriers generally referred as "transport intermediates". These carriers have different shapes and sizes, and their biogenesis, modality of transport, and delivery to the final destination are regulated by a multitude of very complex molecular machineries. A concept that has clearly emerged in the last decade is that each membrane pathway does not represent a close system, but is fully integrated with all the other trafficking pathways. The aim of this book is to provide a general overview of the extent of this crosstalk.
Author | : Jill Lynch |
Publisher | : |
Total Pages | : 0 |
Release | : 2015-03-31 |
Genre | : |
ISBN | : 9781632395009 |
An overview of membrane trafficking pathways has been provided in this all-inclusive book. Membrane traffic is a wide domain that deals with complex exchange of membranes that occurs inside a cell. Protein, lipids and other molecules travel among intracellular organelles, are delivered to or transferred from the cell surface by virtue of membranous carriers known as "transport intermediates." These carriers have distinct shapes and sizes; and their biogenesis, mode of transport and delivery to the final destination are monitored by a multitude of very intricate molecular mechanisms. The concept that every membrane pathway does not represent a close system, but is fully integrated with all the other trafficking pathways has emerged in past few years. This book intends to present a general overview of the degree of this crosstalk.
Author | : Isabelle Couillin |
Publisher | : Springer Science & Business Media |
Total Pages | : 233 |
Release | : 2011-07-02 |
Genre | : Medical |
ISBN | : 3034801483 |
The inflammasome was first described in 2002 as a molecular complex activating proinflammatory caspases and therefore regulating the maturation and biological activities of cytokines such as IL-1 and IL-18. This finding was substantiated by the identification of several mutations in the cias1 gene, encoding the human NLRP3 protein, responsible for several autoinflammatory disorders such as the Muckle Wells syndrome. Since, the interest for this complex has constantly increased and several inflammasome complexes with different specificities have been described. These inflammasomes sense a wide variety of pathogens and danger signals and are key players in the inflammatory response. With the contributions of leading international experts in the field, this book provides an extensive overview of the current knowledge of inflammasome biology and their role in health and disease.
Author | : Heide Schatten |
Publisher | : Springer |
Total Pages | : 395 |
Release | : 2015-08-21 |
Genre | : Science |
ISBN | : 1493929046 |
This volume addresses the structural and functional roles of the cytoskeleton and its dysfunctions which often lead to disease. It provides thorough discussion of microtubules, microfilaments, intermediate filaments, and cytoskeletal functions and dysfunctions in different organ systems. Comprehensive yet concise. The Cytoskeleton In Health And Disease presents cutting-edge discoveries balanced with background information and highlights the new aspects of the research and its impact on the design of new strategies or the identification of new targets for therapeutic intervention. There is a significant need for a book on this topic, as interest in the cytoskeleton continues to grow as causes and cures for cytoskeletal diseases are further explored in biomedical research. This book is essential reading for scientists, students, and teachers interested in expanding their knowledge related to the cytoskeleton. New researchers entering the field will find classic and well as contemporary information not easily found in the current literature or internet resources.
Author | : Monika Schmoll |
Publisher | : Springer |
Total Pages | : 505 |
Release | : 2016-04-04 |
Genre | : Science |
ISBN | : 3319279513 |
Biotechnology has emerged as one of the key environmentally safe technologies for the future which enables use of biomass to develop novel smart materials and to replace oil derived products. Fungi are the most efficient producers of the enzymes needed for this purpose and in addition they produce a plethora of secondary metabolites, among which novel antibiotics can be found. Industrial application and exploitation of the metabolic capacities of fungi requires highly productive and robust gene expression systems, which can be achieved by selection of appropriate species and strain improvement. In this book we aim to summarize homologous and heterologous gene expression systems of fungi for production of enzymes and secondary metabolites. A broad overview on requirements, challenges and successful applications shall serve as a basis for further development of fungi as biotechnological workhorses in research and industry.
Author | : Marta Wilton Vasconcelos |
Publisher | : Frontiers Media SA |
Total Pages | : 170 |
Release | : 2022-10-21 |
Genre | : Science |
ISBN | : 2832503144 |
Author | : Felipe Klein Ricachenevsky |
Publisher | : Frontiers Media SA |
Total Pages | : 400 |
Release | : 2019-09-23 |
Genre | : |
ISBN | : 2889630188 |
Author | : Malgorzata Kloc |
Publisher | : Springer Nature |
Total Pages | : 529 |
Release | : 2019-08-21 |
Genre | : Science |
ISBN | : 3030231739 |
This volume takes a closer look how the cell organelles Golgi apparatus (also known as the Golgi complex or Golgi body), and centriole are structurally and functionally intertwined. Initially, it was believed that the role of Golgi complex is limited to the packaging and preparation for secretion of various cellular proteins, while the centriole participates in cell division and cilia formation. However, since their discovery nearly 200 years ago, it became clear that these two organelles are interacting, and that their functions are much more complex and far reaching than previously thought. Recent findings indicate that the Golgi–Centriole relationship may be important for directional protein transport, cell polarization and cell cycle progression. Current studies indicate that Golgi and centriole also participate in development and act as cellular and immunological sensors, and that their abnormalities lead to cell and developmental abnormalities, Alzheimer, cancer, various lipid disorders and neurological and immunological diseases in humans. This volume combines the latest information on the structure, molecular composition, and roles of Golgi and centriole in various cellular functions and diseases. The better understanding of the Golgi–centriole interactions may lead to the development of novel therapies for the treatment of various diseases, including cancer.
Author | : Christopher Hutchison |
Publisher | : IRL Press |
Total Pages | : 328 |
Release | : 1995 |
Genre | : Medical |
ISBN | : |
The use of developing technologies has revealed the extraordinary degree to which cell cycle control mechanisms have been conserved through eukaryotic evolution. This monograph relates the current scientific understanding of cell cycle control.