Synapse Development and Maturation

Synapse Development and Maturation
Author: Pasko Rakic
Publisher: Academic Press
Total Pages: 560
Release: 2020-05-29
Genre: Psychology
ISBN: 0128236736

Synapse Development and Maturation, the latest release in the Comprehensive Developmental Neuroscience series, presents the latest information on the genetic, molecular and cellular mechanisms of neural development. The book provides a much-needed update that underscores the latest research in this rapidly evolving field, with new section editors discussing the technological advances that are enabling the pursuit of new research on brain development. This volume focuses on the synaptogenesis and developmental sequences in the maturation of intrinsic and synapse-driven patterns. - Features leading experts in various subfields as section editors and article authors - Presents articles that have been peer reviewed to ensure accuracy, thoroughness and scholarship - Includes coverage of mechanisms which regulate synapse formation and maintenance during development - Covers neural activity, from cell-intrinsic maturation, to early correlated patterns of activity

Crëative SYNAPSE©

Crëative SYNAPSE©
Author: Ariel Orama López
Publisher: Palibrio
Total Pages: 305
Release: 2014-03-11
Genre: Self-Help
ISBN: 1463374178

Dr. Ariel Orama López published a new theoretical framework based on Creativity and the recent findings of Neuroscience: the textbook is called CRËATIVE SYNAPSE: CRËATE.YOUR.UNIVERSE© (2013). It is the first theoretical framework that explains the behavior of the human being by integrating the following variables: creativity, neuroscience, and the new influence of the virtual universe. The collection book will be presented in the atrium of the Museo de Arte de Puerto Rico on Wednesday, September 11, 2013, in a distinguished context of artists, health professionals and academics. Dr. Gregory J. Quirk, a prominent American researcher specialized in Neuroscience & Luca Spaghetti, the well-known Italian amico writer -who served as a guide to Elizabeth Gilbert on her journey through Italy while writing Eat Pray Love- elaborated the prologues of this substantial investigative work of thirteen years: they provide in their prologues a nourished and accurate view of this text book, according to their experiences. The art of the book includes the precious paintings and drawings of Ektor Rivera, Celestino & Ramon Bruin (from the Netherlands). The text arises from a practical & theoretical framework created by Dr. Ariel Orama López that departs from his preparation, experience and knowledge in science, human behavior, natural sciences and performing arts. It includes experiences of the author -with a logbook on his sensible hands- in contexts gifted with creativity and spirituality such as Mexico, California, Spain and Italy. The book appeals to artists, academics, psychologists and to the general public. It is published in Spanish and English. It can be acquired in different libraries of the World, including Amazon, Barnes & Nobleand Sony.

Brain Lipids in Synaptic Function and Neurological Disease

Brain Lipids in Synaptic Function and Neurological Disease
Author: Jacques Fantini
Publisher: Academic Press
Total Pages: 398
Release: 2015-05-12
Genre: Medical
ISBN: 0128004924

Lipids are the most abundant organic compounds found in the brain, accounting for up to 50% of its dry weight. The brain lipidome includes several thousands of distinct biochemical structures whose expression may greatly vary according to age, gender, brain region, cell type, as well as subcellular localization. In synaptic membranes, brain lipids specifically interact with neurotransmitter receptors and control their activity. Moreover, brain lipids play a key role in the generation and neurotoxicity of amyloidogenic proteins involved in the pathophysiology of neurological diseases. The aim of this book is to provide for the first time a comprehensive overview of brain lipid structures, and to explain the roles of these lipids in synaptic function, and in neurodegenerative diseases, including Alzheimer's, Creutzfeldt-Jakob's and Parkinson's. To conclude the book, the authors present new ideas that can drive innovative therapeutic strategies based on the knowledge of the role of lipids in brain disorders. - Written to provide a "hands-on" approach for readers - Biochemical structures explained with molecular models, and molecular mechanisms explained with simple drawings - Step-by-step guide to memorize and draw lipid structures - Each chapter features a content summary, up-to-date references for additional study, and a key experiment with an explanation of the technique

The Immune Synapse

The Immune Synapse
Author: Cosima T. Baldari
Publisher: Springer Nature
Total Pages: 518
Release: 2023-04-27
Genre: Science
ISBN: 1071631357

This new collection features the most up-to-date essential protocols that are currently being used to study the immune synapse. Beginning with methods for making biophysical measurements, the volume continues by covering the cell biology of synapses, methods for advanced substrate engineering, mechanobiology topics, new technologies to describe and manipulate synaptic components, as well as methods related to sites of action and immunotherapy. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and fully updated, The Immune Synapse: Methods and Protocols, Second Edition serves as an ideal practical guide for researchers working in this dynamic field. Chapters 5, 11, 18, 27, 30, and 32 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Synaptic Plasticity

Synaptic Plasticity
Author: Thomas Heinbockel
Publisher: BoD – Books on Demand
Total Pages: 224
Release: 2017-06-21
Genre: Medical
ISBN: 9535132334

Nerve cells form thousands of contact points, the synapses, to communicate information with other neurons and target cells. Synapses are sites for changes in brain function through modification of synaptic transmission termed synaptic plasticity. The study of synaptic plasticity has flourished over the years with the advancement of technical breakthroughs and is a timely scientific endeavor today just like it was several decades ago. This book contributes to our understanding of synaptic plasticity at the molecular, biochemical, and cellular systems and behavioral level and informs the reader about its clinical relevance. The book contains ten chapters in three sections: (1) "Mechanisms of Synaptic Plasticity," (2) "Neural Plasticity," and (3) "Plasticity and Neurological Diseases." The book provides detailed and current reviews in these different areas written by experts in their respective fields. The mechanisms of synaptic plasticity and its relation to neurological diseases are featured prominently as a recurring theme throughout most chapters. This book will be most useful for neuroscientists and other scientists alike and will contribute to the training of current and future students who find the plastic nervous system as fascinating as many generations before them.

Neuroanatomy for the XXIst Century

Neuroanatomy for the XXIst Century
Author: Kathleen S. Rockland
Publisher: Frontiers Media SA
Total Pages: 201
Release: 2016-08-15
Genre: Neurosciences. Biological psychiatry. Neuropsychiatry
ISBN: 2889199169

An explosion of new techniques with vastly improved visualization and sensitivity is leading a veritable revolution in modern neuroanatomy. Basic questions related to cell types, input localization, and connectivity are being re-visited and tackled with significantly more accurate and higher resolution experimental approaches. A major goal of this e-Book is thus to highlight in one place the impressive range of available techniques, even as these are fast becoming routine. This is not meant as a technical review, however, but rather will project the technical explosion as indicative of a field now in a vibrant state of renewal. Thus, contributions will be mainly research articles using the newer techniques. A second goal is to showcase what has become the conspicuous interdisciplinary reach of the field: neuroanatomical standards and the close association of structure-function and underlying circuitry mechanisms are increasingly relevant to investigations in development, physiology, and disease. Another feature of this Research Topic is that it includes a breadth of cross-species contributions from investigators working with rodent, nonhuman primate, and human brains. This is important since most of our current knowledge of brain structure has been obtained from experimental animals. However, recent technical advances, coupled with researcher willingness to use the human tissue available, will undoubtedly lead to major advances in the near future regarding human brain mapping and connectomes. Thus, of particular interest will be the methods that can help to define general wiring principles in the brain, both structural and functional. Overall, the state of the field is: exciting.

Insights in Synaptic Neuroscience 2022

Insights in Synaptic Neuroscience 2022
Author: Karri P. Lamsa
Publisher: Frontiers Media SA
Total Pages: 172
Release: 2024-06-20
Genre: Science
ISBN: 2832550509

We are now entering the third decade of the 21st Century, and, especially in the last years, the achievements made by scientists have been exceptional, leading to major advancements in the fast-growing field of Neuroscience. Frontiers has organized a series of Research Topics to highlight the latest advancements in science in order to be at the forefront of science in different fields of research. This editorial initiative of particular relevance, led by Professors Jesper Sjöström, Karri P Lamsa, Alfredo Kirkwood, and supported by the Editorial Board of Frontiers in Synaptic Neuroscience is focused on new insights, novel developments, current challenges, latest discoveries, recent advances, and future perspectives in the field of synaptic neuroscience.