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| Author | : |
| Publisher | : Academic Press |
| Total Pages | : 269 |
| Release | : 2011-09-16 |
| Genre | : Science |
| ISBN | : 0123876982 |
This latest volume in Advances in Genetics covers the genetics of Circadian rhythms. With an international group of authors this volume is the latest offering in this widely praised series.
| Author | : Urs Albrecht |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 306 |
| Release | : 2010-01-23 |
| Genre | : Science |
| ISBN | : 1441912622 |
With the invitation to edit this volume, I wanted to take the opportunity to assemble reviews on different aspects of circadian clocks and rhythms. Although most c- tributions in this volume focus on mammalian circadian clocks, the historical int- duction and comparative clocks section illustrate the importance of various other organisms in deciphering the mechanisms and principles of circadian biology. Circadian rhythms have been studied for centuries, but only recently, a mole- lar understanding of this process has emerged. This has taken research on circadian clocks from mystic phenomenology to a mechanistic level; chains of molecular events can describe phenomena with remarkable accuracy. Nevertheless, current models of the functioning of circadian clocks are still rudimentary. This is not due to the faultiness of discovered mechanisms, but due to the lack of undiscovered processes involved in contributing to circadian rhythmicity. We know for example, that the general circadian mechanism is not regulated equally in all tissues of m- mals. Hence, a lot still needs to be discovered to get a full understanding of cir- dian rhythms at the systems level. In this respect, technology has advanced at high speed in the last years and provided us with data illustrating the sheer complexity of regulation of physiological processes in organisms. To handle this information, computer aided integration of the results is of utmost importance in order to d- cover novel concepts that ultimately need to be tested experimentally.
| Author | : Girdhar K. Pandey |
| Publisher | : Springer Nature |
| Total Pages | : 387 |
| Release | : 2020-09-26 |
| Genre | : Science |
| ISBN | : 3030487334 |
The regulation of the phosphorylation/dephosphorylation process, resulting in “cellular switches” that monitor normal plant physiology, growth and development, has immense potential in crop systems. With much of the information in the nascent stages, coming largely from Arabidopsis and rice particularly, the use of cell biology, genetic screens, biochemical approaches aided by an omics approach should help unravel the detail functional information available about signaling pathways in plants. The regulation could be exploited to develop crop varieties better equipped to handle changing environments and enhance agricultural productivity. In the post-genomic era, one of the major challenges is investigation and understanding of multiple genes and gene families regulating a particular physiological and developmental aspect of plant life cycle. One of the important physiological processes is regulation of stress response, which leads to adaptation or adjustment in response to adverse stimuli. With the holistic understanding of the signaling pathways involving phosphatases, one gene family or multiple genes or gene families, plant biologist can lay a foundation for designing and generating future crops, which can withstand the higher degree of environmental stresses. Especially abiotic stresses, which are the major cause of crop loss throughout the world without losing crop yield and productivity. This book incorporates the contributions from leading plant biologists in the field of stress-mediated dephosphorylation by phosphatases as an important task to elucidate the aspects of stress signaling by functional genomic approaches.
| Author | : David C. Klein |
| Publisher | : Oxford University Press, USA |
| Total Pages | : 498 |
| Release | : 1991 |
| Genre | : Medical |
| ISBN | : 9780195062502 |
Based on a conference funded by the National Institutes of Health, this timely book is the most up-to-date and definitive reference on the suprachiasmatic nucleus (SCN), the part of the brain that controls circadian rhythms in mammals. These biological rhythms range from daily fluctuations in metabolism to seasonal and annual cycles. This book comprehensive and incisive review of the SCN covers anatomy and physiology, intrinsic SCN rhythms, circadian rhythms, neuropharmacology, transplants, and development.
| Author | : J. Philipp Benz |
| Publisher | : Springer Nature |
| Total Pages | : 452 |
| Release | : 2020-10-28 |
| Genre | : Science |
| ISBN | : 3030499243 |
This fully revised third edition includes up-to-date topics and developments in the field, which has made tremendous strides since the publication of the second edition in 2004. Many novel techniques based on Next Generation Sequencing have sped up the analysis of fungi and major advances have been made in genome editing, leading to a deeper understanding of the genetics underlying cellular processes as well as their applicability. At the same time, the relevance of fungi is unbroken, both due to the serious threats to human health and welfare posed by fungal pests and pathogens, and to the many benefits that fungal biotechnology can offer for diverse emerging markets and processes that form the basis of the modern bioeconomy. With regard to these advances, the first section of this volume, Genetics, illustrates the basic genetic processes underlying inheritance, cell biology, metabolism and “lifestyles” of fungi. The second section, Biotechnology, addresses the applied side of fungal genetics, ranging from new tools for synthetic biology to the biotechnological potential of fungi from diverse environments. Gathering chapters written by reputed scientists, the book represents an invaluable reference guide for fungal biologists, geneticists and biotechnologists alike.
| Author | : Jay C. Dunlap |
| Publisher | : Sinauer Associates Incorporated |
| Total Pages | : 406 |
| Release | : 2004 |
| Genre | : Science |
| ISBN | : 9780878931491 |
The study of how solar- and lunar- related rhythms are governed by living pacemakers within organisms constitutes the scientific discipline of chronobiology. Few fields encompass the breadth of science that is associated with this subject, which is at the cutting edge of fields ranging from microbial genetics to ethology to treatment of human psychiatric illnesses. In order to recognise that no individual could do justice to the field in writing a comprehensive text, a group of experienced editors and contributors have collaborated to produce Chronobiology. Written in a clear style and fully illustrated to elucidate difficult points, the book assumes no previous background in neuroscience or maths and reduces technical terminology to a minimum. Examples from the real world and from current and classic research are included.
| Author | : Institute of Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 722 |
| Release | : 1999-05-13 |
| Genre | : Medical |
| ISBN | : 0309173183 |
Every aspect of immune function and host defense is dependent upon a proper supply and balance of nutrients. Severe malnutrition can cause significant alteration in immune response, but even subclinical deficits may be associated with an impaired immune response, and an increased risk of infection. Infectious diseases have accounted for more off-duty days during major wars than combat wounds or nonbattle injuries. Combined stressors may reduce the normal ability of soldiers to resist pathogens, increase their susceptibility to biological warfare agents, and reduce the effectiveness of vaccines intended to protect them. There is also a concern with the inappropriate use of dietary supplements. This book, one of a series, examines the impact of various types of stressors and the role of specific dietary nutrients in maintaining immune function of military personnel in the field. It reviews the impact of compromised nutrition status on immune function; the interaction of health, exercise, and stress (both physical and psychological) in immune function; and the role of nutritional supplements and newer biotechnology methods reported to enhance immune function. The first part of the book contains the committee's workshop summary and evaluation of ongoing research by Army scientists on immune status in special forces troops, responses to the Army's questions, conclusions, and recommendations. The rest of the book contains papers contributed by workshop speakers, grouped under such broad topics as an introduction to what is known about immune function, the assessment of immune function, the effect of nutrition, and the relation between the many and varied stresses encountered by military personnel and their effect on health.
| Author | : P. J. Lumsden |
| Publisher | : Garland Science |
| Total Pages | : 284 |
| Release | : 1998 |
| Genre | : Nature |
| ISBN | : 9781859962169 |
Biological Rhythms and Photoperiodism in Plants brings together disparate subject areas into one accessible text of interest to all plant biologists. In this comprehensive volume, leading international researchers review our current understanding of circadian rhythms from a broad perspective. The book begins with a description of well known rhythmic processes such as gene expression, stomatal guard cell opening, and the movement of petals and leaves. Photoperiodic responses such as dormancy, bulbing, tuberization and flowering are then discussed in terms of their rhythmic behaviour. The latest data from current studies with mutant and transgenic plants is also included.
| Author | : Leon Kreitzman |
| Publisher | : Profile Books |
| Total Pages | : 288 |
| Release | : 2011-09-30 |
| Genre | : Science |
| ISBN | : 1847653723 |
Popular science at its most exciting: the breaking new world of chronobiology - understanding the rhythm of life in humans and all plants and animals. The entire natural world is full of rhythms. The early bird catches the worm -and migrates to an internal calendar. Dormice hibernate away the winter. Plants open and close their flowers at the same hour each day. Bees search out nectar-rich flowers day after day. There are cicadas that can breed for only two weeks every 17 years. And in humans: why are people who work anti-social shifts more illness prone and die younger? What is jet-lag and can anything help? Why do teenagers refuse to get up in the morning, and are the rest of us really 'larks' or 'owls'? Why are most people born (and die) between 3am-5am? And should patients be given medicines (and operations) at set times of day, because the body reacts so differently in the morning, evening and at night? The answers lie in our biological clocks the mechanisms which give order to all living things. They impose a structure that enables us to change our behaviour in relation to the time of day, month or year. They are reset at sunrise and sunset each day to link astronomical time with an organism's internal time.
| Author | : Tilo Strutz |
| Publisher | : Springer Vieweg |
| Total Pages | : 0 |
| Release | : 2015-12-16 |
| Genre | : Technology & Engineering |
| ISBN | : 9783658114558 |
The subject of data fitting bridges many disciplines, especially those traditionally dealing with statistics like physics, mathematics, engineering, biology, economy, or psychology, but also more recent fields like computer vision. This book addresses itself to engineers and computer scientists or corresponding undergraduates who are interested in data fitting by the method of least-squares approximation, but have no or only limited pre-knowledge in this field. Experienced readers will find in it new ideas or might appreciate the book as a useful work of reference. Familiarity with basic linear algebra is helpful though not essential as the book includes a self-contained introduction and presents the method in a logical and accessible fashion. The primary goal of the text is to explain how data fitting via least squares works. The reader will find that the emphasis of the book is on practical matters, not on theoretical problems. In addition, the book enables the reader to design own software implementations with application-specific model functions based on the comprehensive discussion of several examples. The text is accompanied with working source code in ANSI-C for fitting with weighted least squares including outlier detection. Among others the book covers following topics * fitting of linear and nonlinear functions with one- or multi-dimensional variables * weighted least-squares * outlier detection * evaluation of the fitting results * different optimisation strategies * combined fitting of different model functions * total least-squares approach with multi-dimensional conditions
