Computational Phenotypes

Computational Phenotypes
Author: Sergio Balari
Publisher: Oxford University Press
Total Pages: 254
Release: 2013
Genre: Language Arts & Disciplines
ISBN: 019966546X

This is a book about language as a species-typical trait of humans. It argues that language is not so exceptional after all, as according to the authors it is just the human version of a rather common and conservative organic system that they refer to as the Central Computational Complex.

Computational Phenotypes

Computational Phenotypes
Author: Sergio Balari
Publisher: Oxford University Press, USA
Total Pages: 255
Release: 2013
Genre: Language Arts & Disciplines
ISBN: 0199665478

This book, written accessibly for both biologists and linguists, argues that language is not as exceptional a human trait as some linguists believe it to be. It is rather, according to the authors, just the human version of a fairly common and conservative organic system, the Central Computational Complex.

Computational Psychiatry

Computational Psychiatry
Author: A. David Redish
Publisher: MIT Press
Total Pages: 425
Release: 2016-12-09
Genre: Science
ISBN: 0262035421

Psychiatrists and neuroscientists discuss the potential of computational approaches to address problems in psychiatry including diagnosis, treatment, and integration with neurobiology. Modern psychiatry is at a crossroads, as it attempts to balance neurological analysis with psychological assessment. Computational neuroscience offers a new lens through which to view such thorny issues as diagnosis, treatment, and integration with neurobiology. In this volume, psychiatrists and theoretical and computational neuroscientists consider the potential of computational approaches to psychiatric issues. This unique collaboration yields surprising results, innovative synergies, and novel open questions. The contributors consider mechanisms of psychiatric disorders, the use of computation and imaging to model psychiatric disorders, ways that computation can inform psychiatric nosology, and specific applications of the computational approach. Contributors Susanne E. Ahmari, Huda Akil, Deanna M. Barch, Matthew Botvinick, Michael Breakspear, Cameron S. Carter, Matthew V. Chafee, Sophie Denève, Daniel Durstewitz, Michael B. First, Shelly B. Flagel, Michael J. Frank, Karl J. Friston, Joshua A. Gordon, Katia M. Harlé, Crane Huang, Quentin J. M. Huys, Peter W. Kalivas, John H. Krystal, Zeb Kurth-Nelson, Angus W. MacDonald III, Tiago V. Maia, Robert C. Malenka, Sanjay J. Mathew, Christoph Mathys, P. Read Montague, Rosalyn Moran, Theoden I. Netoff, Yael Niv, John P. O'Doherty, Wolfgang M. Pauli, Martin P. Paulus, Frederike Petzschner, Daniel S. Pine, A. David Redish, Kerry Ressler, Katharina Schmack, Jordan W. Smoller, Klaas Enno Stephan, Anita Thapar, Heike Tost, Nelson Totah, Jennifer L. Zick

Phenotypes and Genotypes

Phenotypes and Genotypes
Author: Florian Frommlet
Publisher: Springer
Total Pages: 232
Release: 2016-02-12
Genre: Computers
ISBN: 1447153103

This timely text presents a comprehensive guide to genetic association, a new and rapidly expanding field that aims to elucidate how our genetic code (genotypes) influences the traits we possess (phenotypes). The book provides a detailed review of methods of gene mapping used in association with experimental crosses, as well as genome-wide association studies. Emphasis is placed on model selection procedures for analyzing data from large-scale genome scans based on specifically designed modifications of the Bayesian information criterion. Features: presents a thorough introduction to the theoretical background to studies of genetic association (both genetic and statistical); reviews the latest advances in the field; illustrates the properties of methods for mapping quantitative trait loci using computer simulations and the analysis of real data; discusses open challenges; includes an extensive statistical appendix as a reference for those who are not totally familiar with the fundamentals of statistics.

Computational Systems Bioinformatics

Computational Systems Bioinformatics
Author: Peter Markstein
Publisher: Imperial College Press
Total Pages: 355
Release: 2008
Genre: Mathematics
ISBN: 1848162642

This proceedings volume contains 29 papers covering many of the latest developments in the fast-growing field of bioinformatics. The contributions span a wide range of topics, including computational genomics and genetics, protein function and computational proteomics, the transcriptome, structural bioinformatics, microarray data analysis, motif identification, biological pathways and systems, and biomedical applications.The papers not only cover theoretical aspects of bioinformatics but also delve into the application of new methods, with input from computation, engineering and biology disciplines. This multidisciplinary approach to bioinformatics gives these proceedings a unique viewpoint of the field.

Research in Computational Molecular Biology

Research in Computational Molecular Biology
Author: Terry Speed
Publisher: Springer
Total Pages: 565
Release: 2007-05-18
Genre: Science
ISBN: 3540716815

This book constitutes the refereed proceedings of the 11th Annual International Conference on Research in Computational Molecular Biology, RECOMB 2007, held in Oakland, CA, USA in April 2007. The 37 revised full papers address all current issues in algorithmic, theoretical, and experimental bioinformatics.

Leveraging Data Science for Global Health

Leveraging Data Science for Global Health
Author: Leo Anthony Celi
Publisher: Springer Nature
Total Pages: 471
Release: 2020-07-31
Genre: Medical
ISBN: 3030479943

This open access book explores ways to leverage information technology and machine learning to combat disease and promote health, especially in resource-constrained settings. It focuses on digital disease surveillance through the application of machine learning to non-traditional data sources. Developing countries are uniquely prone to large-scale emerging infectious disease outbreaks due to disruption of ecosystems, civil unrest, and poor healthcare infrastructure – and without comprehensive surveillance, delays in outbreak identification, resource deployment, and case management can be catastrophic. In combination with context-informed analytics, students will learn how non-traditional digital disease data sources – including news media, social media, Google Trends, and Google Street View – can fill critical knowledge gaps and help inform on-the-ground decision-making when formal surveillance systems are insufficient.

Computational Complexity and Statistical Physics

Computational Complexity and Statistical Physics
Author: Allon Percus
Publisher: Oxford University Press
Total Pages: 382
Release: 2006-02-23
Genre: Computers
ISBN: 019976056X

Computer science and physics have been closely linked since the birth of modern computing. In recent years, an interdisciplinary area has blossomed at the junction of these fields, connecting insights from statistical physics with basic computational challenges. Researchers have successfully applied techniques from the study of phase transitions to analyze NP-complete problems such as satisfiability and graph coloring. This is leading to a new understanding of the structure of these problems, and of how algorithms perform on them. Computational Complexity and Statistical Physics will serve as a standard reference and pedagogical aid to statistical physics methods in computer science, with a particular focus on phase transitions in combinatorial problems. Addressed to a broad range of readers, the book includes substantial background material along with current research by leading computer scientists, mathematicians, and physicists. It will prepare students and researchers from all of these fields to contribute to this exciting area.

Algorithms and Computation

Algorithms and Computation
Author: Takao Asano
Publisher: Springer
Total Pages: 791
Release: 2011-12-03
Genre: Computers
ISBN: 3642255914

This book constitutes the refereed proceedings of the 22nd International Symposium on Algorithms and Computation, ISAAC 2011, held in Yokohama, Japan in December 2011. The 76 revised full papers presented together with two invited talks were carefully reviewed and selected from 187 submissions for inclusion in the book. This volume contains topics such as approximation algorithms; computational geometry; computational biology; computational complexity; data structures; distributed systems; graph algorithms; graph drawing and information visualization; optimization; online and streaming algorithms; parallel and external memory algorithms; parameterized algorithms; game theory and internet algorithms; randomized algorithms; and string algorithms.