Computational Neurostimulation

Computational Neurostimulation
Author:
Publisher: Elsevier
Total Pages: 317
Release: 2015-11-16
Genre: Science
ISBN: 0444635475

Computational Neurostimulation, the latest volume in the Progress in Brain Research series provides an introduction to a nascent field with contributions from leading researchers. In addition, it addresses a very timely and relevant issue which has long been known to require more treatment. Part of a well-established international series that examines major areas of basic and clinical research within neuroscience, as well as emerging subfields Provides an introduction to a nascent field with contributions from leading researchers

Brain Stimulation

Brain Stimulation
Author: Cameron C. Mcintyre
Publisher: Elsevier Inc. Chapters
Total Pages: 21
Release: 2013-11-11
Genre: Medical
ISBN: 0128080116

Deep brain stimulation (DBS) is an effective clinical treatment for several medically refractory neurological disorders. However, even after decades of clinical success, explicit understanding of the response of neurons to applied electric fields remains limited, and scientific definition of the therapeutic mechanisms of DBS remains elusive. In addition, it is presently unclear which electrode designs and stimulation paradigms are optimal for maximal therapeutic benefit and minimal side-effects with DBS. Detailed computer modeling of DBS has emerged recently as a powerful technique to enhance our understanding of the effects of DBS and to create a virtual testing ground for new stimulation strategies. This chapter summarizes the fundamentals of neurostimulation modeling, presents some scientific contributions of computer models to the field of DBS, and demonstrates the application of DBS modeling tools to augment the clinical utility of DBS.

Oxford Handbook of Transcranial Stimulation

Oxford Handbook of Transcranial Stimulation
Author: Eric Wassermann
Publisher: Oxford University Press
Total Pages: 773
Release: 2008-01-24
Genre: Medical
ISBN: 0198568924

Transcranial stimulation comprises an important set of techniques for investigating brain function, some of which promise to treat diseases. This book provides a review of the scientific and technical background required to understand transcranial stimulation, for neuroscientists, neurologists, and psychiatrists.

Electrostimulation

Electrostimulation
Author: J. Patrick Reilly
Publisher: Artech House
Total Pages: 353
Release: 2011
Genre: Medical
ISBN: 160807109X

Electrostimulation is defined as the action of electrical energy on nerve and muscle OCo the two classes of excitable tissue. This cutting-edge resource offers you broad coverage of the subject, expanding the scope of electrostimulation discussions to include accidental, aversive, and possibly harmful biological effects of electrical energy. The book enables you to develop standards for human exposure to electric currents having various waveforms, determine classes of nerve fibers brought to excitation within specified regions of the body due to certain types of exposure, and quantify how harmonic distortions influence the excitability of sinusoidal extrostimulation. This practical reference also offers guidance in using the SENN (Spatially Extended Nonlinear Node) computer model that simulates the interaction of applied electric energy with myelinated neurons.Moreover, you learn how to compare efficacy and hazard potential of various stun weapons, assess unintended nerve stimulation from MRI exposure of patients with metallic implants, and compare the safety margins between electrostimulation thresholds of sensory and motor neurons relative to unintended cardiac excitation or painful sensory responses."

Emerging Horizons in Neuromodulation

Emerging Horizons in Neuromodulation
Author:
Publisher: Academic Press
Total Pages: 395
Release: 2012-12-31
Genre: Medical
ISBN: 0124051804

This issue of International Review of Neurobiology brings together cutting-edge research on neuromodulation. It reviews current knowledge and understanding, provides a starting point for researchers and practitioners entering the field, and builds a platform for further research and discovery. Brings together cutting-edge research on neuromodulation Reviews current knowledge and understanding Provides a starting point for researchers and practitioners entering the field, and builds a platform for further research and discovery

Brain-Inspired Computing

Brain-Inspired Computing
Author: Katrin Amunts
Publisher: Springer Nature
Total Pages: 159
Release: 2021-07-20
Genre: Computers
ISBN: 3030824276

This open access book constitutes revised selected papers from the 4th International Workshop on Brain-Inspired Computing, BrainComp 2019, held in Cetraro, Italy, in July 2019. The 11 papers presented in this volume were carefully reviewed and selected for inclusion in this book. They deal with research on brain atlasing, multi-scale models and simulation, HPC and data infra-structures for neuroscience as well as artificial and natural neural architectures.

Essential Neuromodulation

Essential Neuromodulation
Author: Jeffrey Arle
Publisher: Academic Press
Total Pages: 508
Release: 2022-07-11
Genre: Medical
ISBN: 0128170018

Essential Neuromodulation, Second Edition is a concise reference covering all of the basic principles of neuromodulation in a single affordable volume for neuroscientists, residents, fellows, bioengineers and basic clinical practitioners. This second edition expands on developments in the field since 2011, emphasizing essential observations from all of the important clinical phases involved in any neuromodulation: targeting, intraoperative assessment, programming, complications and complication avoidance. As neuromodulation remains an exciting and rapidly advancing field, this information is critical for neurosurgeons, neurophysiologists, bioengineers and other proceduralists. Presents a comprehensive reference on the emerging field of neuromodulation that features chapters from leading physicians and researchers in the field Provides a cohesive presentation of neuromodulation technologies and interventions Contains 550 full-color pages that begin with an overview of the clinical phases involved in neuromodulation, the challenges facing therapies and intraoperative procedures, and innovative solutions for better patient care Emphasizes the fundamentals needed to embrace the neuromodulation field as a cohesive clinical entity Explores the use of electrical, chemical and mechanical interventions to heal and improve neurological deficits Covers the promise of neurostimulation for chronic pain, epilepsy, Parkinson’s disease, and other disorders and diseases Features developments in the field of neuromodulation since the first edition was published, including findings in lead, IPG and accessories

Computational Immunology

Computational Immunology
Author: Shyamasree Ghosh
Publisher: CRC Press
Total Pages: 181
Release: 2020-01-31
Genre: Medical
ISBN: 1351023489

Computational Immunology: Applications focuses on different mathematical models, statistical tools, techniques, and computational modelling that helps in understanding complex phenomena of the immune system and its biological functions. The book also focuses on the latest developments in computational biology in designing of drugs, targets, biomarkers for early detection and prognosis of a disease. It highlights the applications of computational methods in deciphering the complex processes of the immune system and its role in health and disease. This book discusses the most essential topics, including Next generation sequencing (NGS) and computational immunology Computational modelling and biology of diseases Drug designing Computation and identification of biomarkers Application in organ transplantation Application in disease detection and therapy Computational methods and applications in understanding of the invertebrate immune system S Ghosh is MSc, PhD, PGDHE, PGDBI, is PhD from IICB, CSIR, Kolkata, awarded the prestigious National Scholarship from the Government of India. She has worked and published extensively in glycobiology, sialic acids, immunology, stem cells and nanotechnology. She has authored several publications that include books and encyclopedia chapters in reputed journals and books.

The Oxford Handbook of Transcranial Stimulation

The Oxford Handbook of Transcranial Stimulation
Author:
Publisher: Oxford University Press
Total Pages: 1249
Release: 2024-08-14
Genre: Psychology
ISBN: 0192568256

Transcranial stimulation encompasses noninvasive methods that transmit physical fields-such as magnetic, electric, ultrasound, and light-to the brain to modulate its function. The most widespread approach, transcranial magnetic stimulation (TMS), has emerged as an important tool in several areas of neuroscience as well as in clinical applications in psychiatry and neurology. Originally envisioned as a way to measure the responsiveness and conduction speed of neurons and synapses in the brain and spinal cord, TMS has also become an important tool for changing the activity of brain neurons and the functions they subserve as well as an causal adjunct to brain imaging and mapping techniques. Along with transcranial electrical stimulation techniques, TMS has diffused far beyond the borders of clinical neurophysiology and into cognitive, perceptual, behavioural, and therapeutic investigation and attracted a highly diverse group of users and would-be users. Another major success of TMS has been as a treatment in psychiatry, where it is now in routine use worldwide. The field of noninvasive neuromodulation has matured and diversified considerably in the past decade, with an expansion in the number of tools available and our understanding of their mechanisms of action. This second edition of The Oxford Handbook of Transcranial Stimulation brings together the latest developments and important advances in all areas of Transcranial stimulation. The new volume captures the rapid progress made since the first edition, and provides an authoritative and comprehensive review of the state of the art. It also highlights challenges, opportunities, and future directions for this rapidly changing field. The book focuses on the scientific and technical background required to understand transcranial stimulation techniques and a wide-ranging survey of their burgeoning applications in neurophysiology, neuroscience, and therapy. Each of its six sections deals with a major area and is edited by an international authority therein. It will serve researchers, clinicians, students, and others as the definitive text in this area for years to come.

Open questions on the mechanisms of neuromodulation with applied and endogenous electric fields

Open questions on the mechanisms of neuromodulation with applied and endogenous electric fields
Author: Shennan Aibel Weiss
Publisher: Frontiers Media SA
Total Pages: 74
Release: 2015-02-11
Genre: Magnetic brain stimulation
ISBN: 288919373X

Despite increased knowledge, and more sophisticated experimental and modeling approaches, fundamental questions remain about how electricity can interact with ongoing brain function in information processing or as a medical intervention. Specifically, what biophysical and network mechanisms allow for weak electric fields to strongly influence neuronal activity and function? How can strong and weak fields induce meaningful changes in CNS function? How do abnormal endogenous electric fields contribute to pathophysiology? Topics included in the review range from the role of field effects in cortical oscillations, transcranial electrical stimulation, deep brain stimulation, modeling of field effects, and the role of field effects in neurological diseases such as epilepsy, hemifacial spasm, trigeminal neuralgia, and multiple sclerosis.