Comprehensive Chiroptical Spectroscopy Applications In Stereochemical Analysis Of Synthetic Compounds Natural Products And Biomolecules V 2
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Author | : Nina Berova |
Publisher | : John Wiley & Sons |
Total Pages | : 884 |
Release | : 2012-02-17 |
Genre | : Science |
ISBN | : 1118120388 |
This book provides an introduction to the important methods of chiroptical spectroscopy in general, and circular dichroism (CD) in particular, which are increasingly important in all areas of chemistry, biochemistry, and structural biology. The book can be used as a text for undergraduate and graduate students and as a reference for researchers in academia and industry. Experimental methods and instrumentation are described with topics ranging from the most widely used methods (electronic and vibrational CD) to frontier areas such as nonlinear spectroscopy and photoelectron CD, as well as the theory of chiroptical methods and techniques for simulating chiroptical properties. Applications of chiroptical spectroscopy to problems in organic stereochemistry, inorganic stereochemistry, and biochemistry and structural biology are also discussed, and each chapter is written by one or more leading authorities with extensive experience in the field.
Author | : Prasad L. Polavarapu |
Publisher | : CRC Press |
Total Pages | : 298 |
Release | : 2016-10-03 |
Genre | : Science |
ISBN | : 1315357194 |
This book details chiroptical spectroscopic methods: electronic circular dichroism (ECD), optical rotatory dispersion (ORD), vibrational circular dichroism (VCD), and vibrational Raman optical activity (VROA). For each technique, the text presents experimental methods for measurements and theoretical methods for analyzing the experimental data. It also includes a set of experiments that can be adopted for undergraduate teaching laboratories. Each chapter is written in an easy-to-follow format for novice readers, with necessary theoretical formalism in appendices for advanced readers.
Author | : Anil V. Karnik |
Publisher | : Elsevier |
Total Pages | : 622 |
Release | : 2021-07-21 |
Genre | : Science |
ISBN | : 012821063X |
Stereochemistry: A Three-Dimensional Insight draws on the knowledge of its expert authors, providing a systematic treatment on the fundamental aspects of stereochemistry, covering conformational aspects, configurational aspects, effects of bulkiness, stereoelectronic effects on properties of molecules, and the genesis of enantiomerism, among other topics. Visuals and exercises are included to consolidate the principles learned, and the contents are carefully structured to prepare readers for predicting and organizing reaction components to obtain desired stereochemical outcomes. This book is an indispensable guide for all those exploring stereochemistry within their work. The principles of stereochemistry are fundamental to understanding chemical behavior and can provide insights into a whole range of problems, from unusual selectivity and unexpected behaviors, to abnormally fast reactions and surprising biochemical preferences. However, understanding and exploring these 3D effects can be difficult within a 2D medium. This book has been designed to address this problem, providing foundational guidance on the principles and applications of stereochemistry that are fully supported by multimedia visuals. - Combines foundational concepts and definitions with examples of stereochemistry in practice - Highlights the conformational and configurational impact of atomic arrangement on chemical behavior - Outlines methods of analysis - Provides practical exercises and detailed multimedia visuals to support learning
Author | : Maria-Magdalena Cid |
Publisher | : John Wiley & Sons |
Total Pages | : 554 |
Release | : 2015-01-05 |
Genre | : Science |
ISBN | : 3527664637 |
Intended for advanced readers, this is a review of all relevant techniques for structure analysis in one handy volume. As such, it provides the latest knowledge on spectroscopic and related techniques for chemical structure analysis, such as NMR, optical spectroscopy, mass spectrometry and X-ray crystallography, including the scope and limitation of each method. As a result, readers not only become acquainted with the techniques, but also the advantages of the synergy between them. This enables them to choose the correct analytical method for each problem, saving both time and resources. Special emphasis is placed on NMR and its application to absolute configuration determination and the analysis of molecular interactions. Adopting a practical point of view, the author team from academia and industry guarantees both solid methodology and applications essential for structure determination, equipping experts as well as newcomers with the tools to solve any structural problem.
Author | : Carlos A M Afonso |
Publisher | : Royal Society of Chemistry |
Total Pages | : 976 |
Release | : 2020-08-28 |
Genre | : Science |
ISBN | : 183916297X |
This expansive and practical textbook contains organic chemistry experiments for teaching in the laboratory at the undergraduate level covering a range of functional group transformations and key organic reactions.The editorial team have collected contributions from around the world and standardized them for publication. Each experiment will explore a modern chemistry scenario, such as: sustainable chemistry; application in the pharmaceutical industry; catalysis and material sciences, to name a few. All the experiments will be complemented with a set of questions to challenge the students and a section for the instructors, concerning the results obtained and advice on getting the best outcome from the experiment. A section covering practical aspects with tips and advice for the instructors, together with the results obtained in the laboratory by students, has been compiled for each experiment. Targeted at professors and lecturers in chemistry, this useful text will provide up to date experiments putting the science into context for the students.
Author | : A. Douglas Kinghorn |
Publisher | : Springer Nature |
Total Pages | : 344 |
Release | : 2023-01-01 |
Genre | : Science |
ISBN | : 3031104579 |
This book describes a unique class of secondary metabolites, the mono- and dimeric-naphthylisoquinoline alkaloids. They exclusively occur in lianas of the palaeotropical Ancistrocladaceae and Dioncophyllaceae plant families. Their unprecedented structures include stereogenic centers and rotationally hindered, and therefore stereogenic, axes. Extended recent investigations on six Ancistrocladus species from Asia, as reported in this contribution, shed light on their fascinating phytochemical productivity, with over 100 intriguing natural products. This high chemodiversity arises from a similarly unique biosynthesis from acetate-malonate units, following a novel polyketidic pathway to plant-derived isoquinoline alkaloids. Some of the compounds show most promising anti-parasitic activities. Additionally, strategies for the regio- and stereoselective total synthesis of the alkaloids, including the directed construction of the chiral axis, are also presented.
Author | : Dheeraj Kumar Singh |
Publisher | : Springer Nature |
Total Pages | : 388 |
Release | : |
Genre | : |
ISBN | : 9819717035 |
Author | : Natalia V. Kirienko |
Publisher | : Frontiers Media SA |
Total Pages | : 281 |
Release | : 2019-12-24 |
Genre | : |
ISBN | : 2889632563 |
Author | : Harri Lönnberg |
Publisher | : Walter de Gruyter GmbH & Co KG |
Total Pages | : 410 |
Release | : 2024-09-23 |
Genre | : Science |
ISBN | : 3111325636 |
Life in all its forms is based on nucleic acids which store and transfer genetic information. The book addresses main aspects of synthesis, hydrolytic stability and solution equilibria of nucleosides, nucleotides and oligonucleotides, as well as synthesis of their structural analogs that are of interest in chemotherapy. In addition, recent achievements in chemistry of catalytic nucleic acids, development of oligonucleotide based drugs and novel strategies for their targeting and delivery are discussed. The central theme always is the correlation of structure and function.
Author | : Tao Wu |
Publisher | : Frontiers Media SA |
Total Pages | : 148 |
Release | : 2021-04-21 |
Genre | : Science |
ISBN | : 2889667081 |