Completely updated and revised, the 28th edition of this best-selling reference provides instant access to the latest recommendations for treatment of infectious diseases in children. For each disease, the authors provide a commentary to help select the best of all antimicrobial choices. Drug descriptions cover all antimicrobial agents available today and include complete information about dosing regimens. TOPICS INCLUDE Antimicrobial Therapy by Clinical Syndromes Antimicrobial Therapy for Neonates Choosing Among Antibiotics Antifungal Agents Antiviral Agents Antiparasitic Agents Oral Step-down Therapy for Serious Infections Prevention of Symptomatic Infection Approach to Antibiotic Allergies Antibiotic Stewardship New in the 28th Edition Updated recommendations on acute hematogenous osteomyelitis, based on newly published guidelines by the Pediatric Infectious Diseases Society and the Infectious Diseases Society of America, including information on a decrease in the incidence of MRSA infections, allowing the recommendation of cefazolin, again, in empiric therapy for most pediatric bone infections Updated recommendations on influenza treatment and prophylaxis, reflecting American Academy of Pediatrics guidance for 2021-2022 Ceftazidime/avibactam now preferred over fluoroquinolones for treatment of Klebsiella pneumoniae carbapenemase-producing enteric bacilli, if susceptible Cefiderocol, a new iron-binding siderophore cephalosporin class, recently approved in adults for treatment of many drug-resistant pathogens, particularly Acinetobacter, Stenotrophomonas, and Pseudomonas; under study in children New dosing for posaconazole suspension formulation New approaches to mucormycosis Added baloxavir for children 12+ years old Online updates of COVID-19 therapies once emergency use authorization in children at http://www.aap.org/nelsons Updated Nelson's app also available