Chromosome 12 Aberrations In Human Solid Tumors
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| Author | : Jörn Bullerdiek |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 201 |
| Release | : 2013-04-17 |
| Genre | : Medical |
| ISBN | : 3662062550 |
Researchers involved in the cytogenetics and molecular genetics of human tumors will welcome this comprehensive overview of the type of aberrations that chromosome 12 presents in human solid tumors. The authors study the implications for a cytogenetic subtyping of the tumors involved and strategies for identifying the molecular changes which underlie the karyotypic alterations. The aberrations of chromosome 12 which the book deals with are very frequent chromosomal alterations in human tumors occuring in frequent benign mesenchymal tumors, such as uterine leiomyomas and lipomas, and in tumors of epithelial origin, such as pleomorphic adenomas of the salivary glands.
| Author | : S. S. Baig |
| Publisher | : IOS Press |
| Total Pages | : 406 |
| Release | : 1998 |
| Genre | : Medical |
| ISBN | : 9789051994100 |
The pace of discovery, within the EU, of scientific aspects of cancer research and of developments in the clinical field is so rapid that it is sometimes difficult to keep abreast. This brief overview attempts to highlight some of the advances in the field, as part of BIOMED programme funded research and specific results due to the co-operative spirit established by the scientific community. It is particularly worth noting the financial investment of 35 million ECU in the current programme, has d as a catalyst in attracting a large number of Member States funded research in pooling their collective knowledge base.
| Author | : Jörn Bullerdiek |
| Publisher | : Springer |
| Total Pages | : 194 |
| Release | : 1994-01-01 |
| Genre | : Cancer |
| ISBN | : 9780387557595 |
| Author | : Marcelo Larramendy |
| Publisher | : BoD – Books on Demand |
| Total Pages | : 206 |
| Release | : 2017-08-30 |
| Genre | : Medical |
| ISBN | : 9535134736 |
This edited book, Chromosomal Abnormalities - A Hallmark Manifestation of Genomic Instability, contains a series of chapters highlighting several aspects related to the generation of chromosomal abnormalities in genetic material. We are extremely grateful to the authors who had contributed with valuable information about the role of genomic instability in pathological disorders as well as in the evolution process.
| Author | : Peining Li |
| Publisher | : Springer Nature |
| Total Pages | : 520 |
| Release | : |
| Genre | : |
| ISBN | : 3031475305 |
| Author | : |
| Publisher | : |
| Total Pages | : 1284 |
| Release | : 1988 |
| Genre | : Medicine |
| ISBN | : |
| Author | : |
| Publisher | : |
| Total Pages | : 1060 |
| Release | : 1990 |
| Genre | : Medicine |
| ISBN | : |
| Author | : Leon P. Bignold |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 398 |
| Release | : 2006 |
| Genre | : Health & Fitness |
| ISBN | : 9783764371562 |
Tumors can be induced by a variety of physical and chemical carcinogens. The resulting tumor cells are usually abnormal in their morphology and behavior and transmit their abnormalities to their daughter tumor cells. Most theories of the pathogenesis of tumors suggest that carcinogens in some way cause alterations either of the genomes or of inheritable patterns of gene expression in normal cells, which then cause morphological and behavioral changes. This volume presents a collection of articles aimed at the question by what genetic or epigenetic mechanisms carcinogens can cause morphological abnormalities of tumor cells. It includes reviews of cellular targets of known carcinogens, and presents varying viewpoints of how morphological abnormalities and the actions of carcinogens might be related. The volume will be of interest to all those who are involved in cancer research or in the prevention, diagnosis or management of tumors in humans or animals.
| Author | : Sverre Heim |
| Publisher | : John Wiley & Sons |
| Total Pages | : 645 |
| Release | : 2015-06-29 |
| Genre | : Medical |
| ISBN | : 1118795512 |
The first three editions of this acclaimed book presented a much-needed conceptual synthesis of this rapidly moving field. Now, Cancer Cytogenetics, Fourth Edition, offers a comprehensive, expanded, and up-to-date review of recent dramatic advances in this area, incorporating a vast amount of new data from the latest basic and clinical investigations. New contributors reflecting broader international authorship and even greater expertise Greater emphasis throughout on the clinical importance and application of information about cytogenetic and molecular aberrations Includes a complete coverage of chromosome aberrations in cancer based on an assessment of the 60,000 neoplasms cytogenetically investigated to date Now produced in full color for enhanced clarity Covers how molecular genetic data (PCR-based and sequencing information) are collated with the cytogenetic data where pertinent Discusses how molecular cytogenetic data (based on studies using FISH, CGH, SNP, etc) are fused with karyotyping data to enable an as comprehensive understanding of cancer cytogenetics as is currently possible
| Author | : Gerard Morel |
| Publisher | : CRC Press |
| Total Pages | : 376 |
| Release | : 1993-06-09 |
| Genre | : Science |
| ISBN | : 9780849344145 |
Hybridization Techniques for Electron Microscopy examines the use of in situ hybridization techniques, including an overview of current perspectives and future developments. The book features in situ methods for fluorescence probes and confocal scanning microscopes. Three in situ hybridization methods for electron microscopes are analyzed: the non-embedded tissue method using ultrathin frozen sections, pre-embedded method, and post-embedded method using material embedded in hydrophilic resin. Positive and negative features are discussed, and clear instructions regarding implementation of techniques are provided. Particular aspects of the techniques are examined in detail, such as preparation of tissue, pretreatment, hybridization procedures, revelation (autoradiography and immunocytology) and checking procedures, in addition to the illustration, interpretation, and discussion of methods and results. The main applications described include virus detection, chromosomal gene mapping, detection of ribosomic nucleic acid, and detection of messenger RNA in animals and plants. Hybridization Techniques for Electron Microscopy is an excellent reference for cytologists, cell biologists, histochemists, cytochemists, molecular endocrinologists, and neuroendocrinologists.
