Cerebral Amyloid Angiopathy In Alzheimers Disease And Related Disorders
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Author | : M.M. Verbeek |
Publisher | : Springer Science & Business Media |
Total Pages | : 359 |
Release | : 2013-06-29 |
Genre | : Medical |
ISBN | : 9401710074 |
Cerebral amyloid angiopathy (CAA) is a distinctive abnormality of small cerebral blood vessels, one that has intrigued neuroscientists for decades. The time seems right for a book which examines the phenomenon of CAA using a multifaceted approach: What does it produce clinically? How might CAA be imaged? What are the crucial biochemical/cellular events within cerebral vessel walls that lead to CAA? How can in vitro or transgenic experimental systems be used to understand the etiology of, or even potential treatments for, CAA? The editors have assembled key figures in the field of CAA research to examine these (and other) questions in a series of focused chapters that address specific issues of importance in understanding CAA and its clinical manifestations. Comprehending the biology and pathogenesis of this fascinating vascular lesion may even provide clues to less common forms of cerebral microvascular disease that have been recognized for decades (hypertensive microangiopathy) or more recently (CADASIL).
Author | : David J. Werring |
Publisher | : Cambridge University Press |
Total Pages | : 207 |
Release | : 2011-05-26 |
Genre | : Medical |
ISBN | : 1139496212 |
Stroke is a leading cause of death and disability throughout the world. About one in three symptomatic strokes are due to disease of small perforating arteries; however, most effective interventions are targeted at disease of large arteries. The underlying mechanisms and treatment of small vessel disease remain poorly understood. Microbleeds have emerged as a critical imaging marker of small vessel disease, being found in all types of stroke. With increasing evidence that microbleeds are caused by hypertensive arteriopathy and cerebral amyloid angiopathy, they are likely to play a strong future role in increasing our understanding of the causes of small vessel disease and the potential link between cerebrovascular disease and neurodegeneration. Cerebral Microbleeds summarizes our current knowledge, bringing together expert research from global authorities in the field. This authoritative and systematic text will be of interest to all clinical researchers and physicians in the fields of stroke and cognitive impairment.
Author | : Masud Husain |
Publisher | : Oxford University Press |
Total Pages | : 513 |
Release | : 2018-10-29 |
Genre | : Clinical neuropsychology |
ISBN | : 0198831080 |
This volume covers the dramatic developments that have occurred in basic neuroscience and clinical research in cognitive neurology and dementia. It is based on the clinical approach to the patient, and provides essential knowledge that is fundamental to clinical practice.
Author | : Serge Gauthier |
Publisher | : CRC Press |
Total Pages | : 226 |
Release | : 2005-09-22 |
Genre | : Medical |
ISBN | : 0203931742 |
A progress report on the cutting-edge research into Alzheimer‘s Disease and other forms of dementia, this important volume has particular emphasis on topics that are applicable to clinical practice.In this latest instalment, Serge Gauthier, Philip Scheltens and Jeffrey Cummings cover some of the emerging therapies for Alzheimer‘s Disease, including
Author | : Julien Bogousslavsky |
Publisher | : Cambridge University Press |
Total Pages | : 418 |
Release | : 2001-05-24 |
Genre | : Medical |
ISBN | : 9780521771450 |
An essential resource for diagnosis and treatment of stroke patients outside the usual clinical categories.
Author | : Velandai Srikanth |
Publisher | : Academic Press |
Total Pages | : 322 |
Release | : 2018-02-09 |
Genre | : Medical |
ISBN | : 0128096942 |
Type 2 Diabetes and Dementia details the relationship between diabetes, dementia and the future of medicine and therapeutics. Chapters range from epidemiology, clinical features, neuroimaging biomarkers, neuropathology, macrostructural and molecular mechanisms, risk assessment and prevention strategies, and the application of therapeutics. The book reflects the translational aspects of the current science in the field, with an emphasis on the display of neuroimaging and neuropathology. It contains contributions from world experts, and is ideal for clinicians and researchers in the fields of neurology, neuroscience, geriatric medicine and endocrinology. Presents a comprehensive overview that details the relationship between diabetes, dementia and the future of medicine and therapeutics Written for researchers and clinicians in neurology, neuroscience, geriatric medicine and endocrinology Includes topics ranging from epidemiology, clinical features, neuroimaging biomarkers, neuropathology, macrostructural and molecular mechanisms, risk assessment, prevention strategies and therapeutic applications
Author | : Raffaella Valenti |
Publisher | : Firenze University Press |
Total Pages | : 184 |
Release | : 2018 |
Genre | : |
ISBN | : 8864537783 |
Author | : |
Publisher | : ScholarlyEditions |
Total Pages | : 55 |
Release | : 2012-12-26 |
Genre | : Medical |
ISBN | : 1481613944 |
Cerebral Arterial Diseases—Advances in Research and Treatment: 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Cerebral Arterial Diseases in a concise format. The editors have built Cerebral Arterial Diseases—Advances in Research and Treatment: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Cerebral Arterial Diseases in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Cerebral Arterial Diseases—Advances in Research and Treatment: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Author | : Robert Marr |
Publisher | : Frontiers Media SA |
Total Pages | : 112 |
Release | : 2015-03-24 |
Genre | : Neurosciences. Biological psychiatry. Neuropsychiatry |
ISBN | : 2889194434 |
Strong evidence continues to accumulate indicating that amyloid-beta (Aß) is a central part of Alzheimer’s disease (AD) pathogenesis in spite of the negative evidence coming from failed clinical trials. Therefore, mechanisms of clearance of Aß are of great interest in understanding AD pathogenesis and the development of effective treatments. This topic focuses on the issues related to Aß clearance in AD. The topics covered include proteases that degrade Aß and their localization, regulation, and functions. This topic also covers issues related to clearance through uptake by glia and through low-density lipoprotein (LDL) receptor mediated mechanisms. Signal transduction related to AD pathology and clearance is also addressed. Finally, immunotherapy and other novel therapeutic approaches are discussed.
Author | : |
Publisher | : |
Total Pages | : 1368 |
Release | : 1989 |
Genre | : Alzheimer's disease |
ISBN | : |