Coco the family dog has been dog-napped! When Snowflake the cat is forced to take over for Coco as Danny's trucking buddy, the fussy feline is at first down on the idea of traveling in an 18-wheeler until she has a change of heart and decides to become the greatest truck-driving cat, EVER! Conflicts arise when Danny is assigned a bullying partner, and his sidekick (a street-tough Chihuahua), to haul a high security load across America. Halloween right around the corner, it's yowling and howling hilarity as Snowflake, the (Gato Diablo), and Paco (Count Dracula), give the bad guys more than they bargained for. All the while, Danny finds himself butting heads with thieves, mobsters, dirty cops, and a beautiful but mysterious woman. Angels and devils collide as Danny's runaway truck plunges down a mountainside with Snowflake at the wheel and bad guys in hot pursuit. Raising one paw to the air, she voices her challenge to a dark world, "TAKE THAT!"