Cartilage Tissue And Knee Joint Biomechanics
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| Author | : Amirsadegh Rezazadeh Nochehdehi |
| Publisher | : Elsevier |
| Total Pages | : 765 |
| Release | : 2023-09-05 |
| Genre | : Technology & Engineering |
| ISBN | : 0323907210 |
Cartilage, Tissue and Knee Joint Biomechanics: Fundamentals, Characterization and Modelling is a cutting-edge multidisciplinary book specifically focused on modeling, characterization and related clinical aspects. The book takes a comprehensive approach towards mechanics, fundamentals, morphology and properties of Cartilage Tissue and Knee Joints. Leading researchers from health science, medical technologists, engineers, academics, government, and private research institutions across the globe have contributed to this book. This book is a very valuable resource for graduates and postgraduates, engineers and research scholars. The content also includes comprehensive real-world applications. As a reference for the total knee arthroplasty, this book focuses deeply on existing related theories (including: histology, design, manufacturing and clinical aspects) to assist readers in solving fundamental and applied problems in biomechanical and biomaterials characterization, modeling and simulation of human cartilages and cells. For biomedical engineers dealing with implants and biomaterials for knee joint injuries, this book will guide you in learning the knee anatomy, range of motion, surgical procedures, physiological loading and boundary conditions, biomechanics of connective soft tissues, type of injuries, and more. - Provides a comprehensive resource on the knee joint and its connective soft tissues; content included spans biomechanics, biomaterials, biology, anatomy, imaging and surgical procedure - Covers ISO and FDA based regulatory control and compliance in the manufacturing process - Includes discussions on the relationship between knee anatomical parameters and knee biomechanics
| Author | : Kyriacos Athanasiou |
| Publisher | : Springer Nature |
| Total Pages | : 174 |
| Release | : 2022-06-01 |
| Genre | : Science |
| ISBN | : 3031025784 |
Cartilage injuries in children and adolescents are increasingly observed, with roughly 20% of knee injuries in adolescents requiring surgery. In the US alone, costs of osteoarthritis (OA) are in excess of $65 billion per year (both medical costs and lost wages). Comorbidities are common with OA and are also costly to manage. Articular cartilage's low friction and high capacity to bear load makes it critical in the movement of one bone against another, and its lack of a sustained natural healing response has necessitated a plethora of therapies. Tissue engineering is an emerging technology at the threshold of translation to clinical use. Replacement cartilage can be constructed in the laboratory to recapitulate the functional requirements of native tissues. This book outlines the biomechanical and biochemical characteristics of articular cartilage in both normal and pathological states, through development and aging. It also provides a historical perspective of past and current cartilage treatments and previous tissue engineering efforts. Methods and standards for evaluating the function of engineered tissues are discussed, and current cartilage products are presented with an analysis on the United States Food and Drug Administration regulatory pathways that products must follow to market. This book was written to serve as a reference for researchers seeking to learn about articular cartilage, for undergraduate and graduate level courses, and as a compendium of articular cartilage tissue engineering design criteria. Table of Contents: Hyaline Articular Cartilage / Cartilage Aging and Pathology / In Vitro / Bioreactors / Future Directions
| Author | : Van C. Mow |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 464 |
| Release | : 2012-12-06 |
| Genre | : Technology & Engineering |
| ISBN | : 1461234484 |
Historical folklore indicates that Asklepios (circa 900 BC), the fir~t western doctor of ancient Greece, treated many patients with rheumatic diseases of 1 joints ,2. Later, Hippocrates (circa 400 BC), who claimed to have learned from Asklepios, used the term arthritis in reference to joint diseases: "When the disease of arthritis strikes, acute inflammation and pain attacks the joints of the body ... ". Indeed, arthritic joint disease dates much farther back into antiquity than Asklepios. Many modern anthropologists have noted degenerative joint disease in the fossils of Neanderthal man (archanthropus europeus petraloniensis) and even in those of dinosaurs. More recent scientific studies on joints date back to the work of the great English anatomist Hunter who wrote "The Structure and Diseases of Articular Cartilage" in the Philosophical Transactions of London in 1743. The notion that osteoarthritis results from the wearing away of cartilage was copiously documented by the histological observations of the German physician Ecker in 1843. This idea was further supported by Pommer (1927) who felt that mechanical stresses played important roles in the initiation and propagation of cartilage lesions leading to osteoarthritis. This same conclusion was reached by the assembled distinguished experts at a National Institutes of Health Workshop 3 held in 1986 .
| Author | : Kyriacos A. Athanasiou |
| Publisher | : CRC Press |
| Total Pages | : 425 |
| Release | : 2017-01-06 |
| Genre | : Medical |
| ISBN | : 1439853258 |
Well-known for their inability to heal, articular cartilage injuries often degenerate inexorably to disastrous impairment. Multitudes of treatments have been devised for this problem, but no satisfactory long-term solutions have been established. Written by world-class experts, Articular Cartilage covers the latest research and advancements related to biology, development, pathology, clinical applications, and tissue engineering. This book is useful for rheumatologists, orthopaedic surgeons, cartilage biologists, and cartilage engineers as well as for professionals working in the orthopaedic and other musculoskeletal industries. This book also belongs in the library of primary care physicians, gerontologists, physical therapists, kinesiologists, and chiropractors. Written at a level that allows accessibility to a wide audience, it provides an interdisciplinary approach that encompasses the breadth and depth of basic science, bioengineering, translational science, and detailed methodologic approaches. The authors examine the major events and signaling molecules that lead to development of articular cartilage from precursor cells, and the changes in cartilage as it matures and ages. They focus on the epidemiology, etiopathogenesis, and therapeutic approaches for cartilage injury and the major arthritides that affect cartilage and the synovial joints such as osteoarthritis, rheumatoid arthritis, and gout. They supply an up-to-date overview of the field of tissue engineering as applied to articular cartilage repair. They examine a number of methods used to assess structure, composition, biology, and biomechanical function. Each chapter contains extensive references to enhance additional study. The book’s comprehensive focus on multiple aspects of articular cartilage sets it apart from other tissue engineering or developmental biology-based books available. It includes important discussions and perspectives on many of the remaining challenges and opportunities in the development and translation of new approaches for treating diseases of articular cartilage. It also provides detailed working protocols for many of the methods used to study articular cartilage, coverage of current treatment options, and business and regulatory aspects of the development of cartilage products. It provides a deeper understanding that will help with the development of new products and clinical applications.
| Author | : James P. Stannard |
| Publisher | : Thieme |
| Total Pages | : 364 |
| Release | : 2013-04-15 |
| Genre | : Medical |
| ISBN | : 1604068590 |
Articular Cartilage Injury of the Knee is a comprehensive reference that combines the basic scientific knowledge of articular cartilage as it relates to patient health and disease with patient-focused diagnosis and treatment options. This book emphasizes the importance of bridging the divide between basic science and clinical applications in order to select the best possible treatment when injuries occur. Key Features: Provides clinically-relevant information on each topic that can easily be applied in practice Showcases the latest techniques in transplantation and scaffolds for cartilage repair Includes a focused chapter on assessment outcomes after cartilage repair of the knee Written and edited by leading orthopedic surgeons and basic science experts who represent the most current philosophy of effective management of articular cartilage injury of the knee Orthopedic surgeons specializing in the lower extremity will find this book to be an excellent resource that they can consult to guide them in the treatment of patients with articular cartilage injury of the knee.
| Author | : J. F. Stoltz |
| Publisher | : IOS Press |
| Total Pages | : 460 |
| Release | : 2006 |
| Genre | : Medical |
| ISBN | : 9781586036485 |
Over recent years, there has been increasing interest in the fundamental role played by local mechanical parameters in chondrocyte regulation and cartilage dysfunction as a first step in the development of osteoarthritis. This is how the idea of mechanobiology and the concept of mechanotransduction were born in the 90's. Indeed, a broad diversity of physiological phenomena is induced by mechanical stimuli (hearing, orientation to gravity, touch, tissue remodeling...) but the mechanism by which mechanical forces may regulate a physiological response is still unknown. In other respects, the concept of regenerative medicine has recently developed in parallel to this. Regenerative medicine is an emerging multidisciplinary field involving medicine, biology, chemistry, mechanics and engineering that is likely to revolutionize the ways we improve the health and quality of life by restoring, maintaining or enhancing tissue and organ functions. Indeed, human tissues do not regenerate spontaneously and healing is only a stopgap that may be associated with contraction which in turn may prevent regeneration. interesting alternative. Today, the in vitro preparation of biological tissues such as cartilage, bone, tendon, vessel, heart muscle, skin, brings out major expectations for the next decade. However, to each type of tissue correspond a large number of potential methods related to the support, the cells used (tissular cells or stem cells) and to the conditions of the environment (culture medium and mechanical forces). The aim of this publication is to provide a thoughtful and balanced view on new crucial concepts with clinical implications.
| Author | : Sayeed Ahmed MCSP |
| Publisher | : Xlibris Corporation |
| Total Pages | : 159 |
| Release | : 2019 |
| Genre | : Science |
| ISBN | : 1984589563 |
The structural and mechanical properties of different tissues of the knee deteriorate progressively, causing pain and disability in people with knee osteoarthritis (OA). However these tissues can remodel themselves in response to mechanical demand placed on them. Therefore an appropriate physical management strategy can reverse degenerative process of the tissues around the knee OA. This in turn can be effective to reduce pain, improve function of the knee joint and hinder the disabling process in people with knee OA. This book has highlighted: - The structural and mechanical properties of the joint tissues as well as their remodelling properties. - The physiopathology that produces pain in OA is discussed. - Finally physical management strategy is discussed.
| Author | : J. Whit Ewing |
| Publisher | : Lippincott Williams & Wilkins |
| Total Pages | : 434 |
| Release | : 1990 |
| Genre | : Medical |
| ISBN | : |
| Author | : H. J. Helminen |
| Publisher | : Butterworth-Heinemann |
| Total Pages | : 460 |
| Release | : 1987 |
| Genre | : Medical |
| ISBN | : |
| Author | : R.P. Jakob |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 1024 |
| Release | : 2012-12-06 |
| Genre | : Medical |
| ISBN | : 3642844634 |
This book summarizes the experience gained by the Orthopedic Study Group for the Knee (OAK) of the Swiss Orthopedic Society in dealing with knee problems relating to deficiencies of the cruciate ligaments. The editors, R.P. Jakob and H.-U.Staubli, have collaborated with international authorities to produce this ex cellent work dealing with a great many aspects of knee surgery and especially the problems of the cruciate ligaments. For clarity, the book begins with definitions and explanations of basic biomechan ical terms. The chapters on Anatomy and Biomechanics present up-to-date scien tific information based on anatomic and biomechanical principles as they are ap plied in modern knee surgery. The second part of the book focuses on the OAK-sanctioned approach to knee documentation and evaluation, which is a valuable supplement to other knee evaluation schemes. The European Society for Knee Surgery (ESKA) and the American Orthopedic Society for Sports Medicine (AOSSM) are currently at tempting to combine the advantages of the OAK system with an internationally valid evaluation scheme to create a standard evaluation and documentation sys tem that will be acceptable to all physicians.
