Cannabinoids And Their Receptors
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| Author | : Institute of Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 288 |
| Release | : 1999-07-10 |
| Genre | : Medical |
| ISBN | : 0309071550 |
The medical use of marijuana is surrounded by a cloud of social, political, and religious controversy, which obscures the facts that should be considered in the debate. This book summarizes what we know about marijuana from evidence-based medicineâ€"the harm it may do and the relief it may bring to patients. The book helps the reader understand not only what science has to say about medical marijuana but also the logic behind the scientific conclusions. Marijuana and Medicine addresses the science base and the therapeutic effects of marijuana use for medical conditions such as glaucoma and multiple sclerosis. It covers marijuana's mechanism of action, acute and chronic effects on health and behavior, potential adverse effects, efficacy of different delivery systems, analysis of the data about marijuana as a gateway drug, and the prospects for developing cannabinoid drugs. The book evaluates how well marijuana meets accepted standards for medicine and considers the conclusions of other blue-ribbon panels. Full of useful facts, this volume will be important to anyone interested in informed debate about the medical use of marijuana: advocates and opponents as well as policymakers, regulators, and health care providers.
| Author | : Vincenzo Di Marzo |
| Publisher | : John Wiley & Sons |
| Total Pages | : 326 |
| Release | : 2014-07-18 |
| Genre | : Science |
| ISBN | : 1118451279 |
Cannabinoids ‘Cannabinoids’ is a broad term covering a group of natural products from Cannabis sativa, one of which locks on to specific receptors – protein molecules on the surface of cells – known as cannabinoid receptors. Over the past decades scientists have found that cannabinoid receptors and their endogenous ligands, the endocannabinoids, are involved in a vast array of physiological functions, including helping to control brain activity, energy metabolism, heart function, the immune system and even reproduction. In Cannabinoids, Vincenzo Di Marzo has assembled contributions from international experts to provide the definitive guide to what continues to be a rapidly developing research field. After an introductory historical chapter, the book continues by looking at the biochemical, genetic and molecular elements of cannabinoids, followed by chapters covering their role in health and disease. The final chapter outlines the need for a new nomenclature to reflect the complex and multi-disciplinary nature of this area. An authoritative guide to the history, development and possible future of cannabinoid research. Includes contributions from leading international experts in the field. Clearly written, well organised and logically presented. Cannabinoids will prove invaluable to researchers, practitioners and students across a wide range of disciplines, needing an up-to-date guide to this significant area of research.
| Author | : A. Douglas Kinghorn |
| Publisher | : Springer |
| Total Pages | : 137 |
| Release | : 2017-01-24 |
| Genre | : Science |
| ISBN | : 3319455419 |
The book presents the current state of the art on phytocannnabinoid chemistry and pharmacology and will be of much use to those wishing to understand the current landscape of the exciting and intriguing phytocannabinoid science. The focus is on natural product cannabinoids which have been demonstrated to act at specific receptor targets in the CNS.
| Author | : Timmen L. Cermak |
| Publisher | : Cambridge University Press |
| Total Pages | : 257 |
| Release | : 2020-04-02 |
| Genre | : Medical |
| ISBN | : 1108597572 |
The trend toward liberalizing medical and recreational marijuana use is increasing the obligation on clinicians to provide useful information to the public. This book summarizes the science all healthcare professionals need to know in order to provide objective and relevant information to a variety of patients, from recreational and medicinal users to those who use regularly, and to adolescents and worried parents. The author brings two and a half decades of studying cannabinoid research, and over forty years' experience in psychiatric and addiction medicine practice, to shed light on the interaction between marijuana and the brain. Topics range from how marijuana produces pleasurable sensations, relaxation and novelty (the 'high'), to emerging medical uses, effects of regular use, addiction, and policy. Principles of motivational interviewing are outlined to help clinicians engage patients in meaningful, non-judgmental conversations about their experiences with marijuana. An invaluable guide for physicians, nurses, psychologists, therapists, and counsellors.
| Author | : Mahmoud A. ElSohly |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 323 |
| Release | : 2007-11-15 |
| Genre | : Medical |
| ISBN | : 1592599478 |
Although primarily used today as one of the most prevalent illicit leisure drugs, the use of Cannabis sativa L., commonly referred to as marijuana, for medicinal purposes has been reported for more than 5000 years. Marijuana use has been shown to create numerous health problems, and, consequently, the expanding use beyond medical purposes into recreational use (abuse) resulted in control of the drug through international treaties. Much research has been carried out over the past few decades following the identification of the chemical structure of THC in 1964. The purpose of Marijuana and the Cannabinoids is to present in a single volume the comprehensive knowledge and experience of renowned researchers and scientists. Each chapter is written independently by an expert in his/her field of endeavor, ranging from the botany, the constituents, the chemistry and pharmacokinetics, the effects and consequences of illicit use on the human body, to the therapeutic potential of the cannabinoids.
| Author | : Mary E. Abood |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 286 |
| Release | : 2013 |
| Genre | : Cannabinoids |
| ISBN | : 1461446686 |
The cloning of two G protein-coupled cannabinoid receptors, termed CB1 and CB2, in the early 1990s has stimulated and facilitated research conducted on the physiological function of cannabinoid actions in the brain and throughout the body. In the twenty years since the identification of these two receptors, endogenous ligands (endocannabinoids) for these receptors have been identified, their biosynthetic and metabolic pathways have been discerned, and their functional and regulatory action for signalling through CB1 and CB2 receptors have been described. More recently, it has become has become evident that cannabinoids exert actions at non-CB1, non-CB2 receptors. Much less is understood about these actions. Many of these novel?targets? are in the process of being characterized functionally and physiologically, and the therapeutic value of targeting these non-CB1, non-CB2 receptors is being evaluated. The purpose of this volume is to present the current knowledge on the atypical actions of cannabinoids on these new targets. This book is intended as a scientific resource for cannabinoid researchers carrying out animal and human experiments, and for those who are interested in learning about future directions in cannabinoid research. Additionally, this book may be of value to investigators currently working outside the field of cannabinoid research who have an interest in learning about these compounds and their atypical cannabinoid signalling. This book provides insight into the potential medical application of cannabinoids and their therapeutic development for the treatment of human disease.
| Author | : Laura L. Murphy |
| Publisher | : CRC Press |
| Total Pages | : 604 |
| Release | : 2019-06-04 |
| Genre | : Science |
| ISBN | : 1000006174 |
First Published in 1992, Marijuana/Cannabinoids: Neurophysiology and Neurobiology is the first book to specifically address the effects of marijuana and cannabinoids on the physiology and behavior of the brain. The book discusses the dramatic effects of marijuana use on brain chemistry, pharmacology, and behavior. It also examines the isolation of natural cannabinoids and the synthesis of new cannabinoid-like compounds that have been important in research leading to the discovery and function of the cannabinoid receptor in the brain. Up-to-date research findings and in-depth reviews on marijuana and cannabinoids in the brain and their potential therapeutic value make Marijuana/Cannabinoids: Neurophysiology and Neurobiology essential for students, practitioners, and researchers involved in researching drugs of abuse.
| Author | : Attila Köfalvi |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 587 |
| Release | : 2007-12-22 |
| Genre | : Medical |
| ISBN | : 0387743499 |
Endocannabinoids have tremendous therapeutic potential. This book introduces readers to our current understanding of the neurobiology of endocannabinoids and related systems, detailing their pathophysiological role and therapeutic potential. Authors, experienced clinical investigators, present and analyze results of recent clinical trials as well as the development of new therapeutic strategies and medicines.
| Author | : National Academies of Sciences, Engineering, and Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 487 |
| Release | : 2017-03-31 |
| Genre | : Science |
| ISBN | : 0309453070 |
Significant changes have taken place in the policy landscape surrounding cannabis legalization, production, and use. During the past 20 years, 25 states and the District of Columbia have legalized cannabis and/or cannabidiol (a component of cannabis) for medical conditions or retail sales at the state level and 4 states have legalized both the medical and recreational use of cannabis. These landmark changes in policy have impacted cannabis use patterns and perceived levels of risk. However, despite this changing landscape, evidence regarding the short- and long-term health effects of cannabis use remains elusive. While a myriad of studies have examined cannabis use in all its various forms, often these research conclusions are not appropriately synthesized, translated for, or communicated to policy makers, health care providers, state health officials, or other stakeholders who have been charged with influencing and enacting policies, procedures, and laws related to cannabis use. Unlike other controlled substances such as alcohol or tobacco, no accepted standards for safe use or appropriate dose are available to help guide individuals as they make choices regarding the issues of if, when, where, and how to use cannabis safely and, in regard to therapeutic uses, effectively. Shifting public sentiment, conflicting and impeded scientific research, and legislative battles have fueled the debate about what, if any, harms or benefits can be attributed to the use of cannabis or its derivatives, and this lack of aggregated knowledge has broad public health implications. The Health Effects of Cannabis and Cannabinoids provides a comprehensive review of scientific evidence related to the health effects and potential therapeutic benefits of cannabis. This report provides a research agendaâ€"outlining gaps in current knowledge and opportunities for providing additional insight into these issuesâ€"that summarizes and prioritizes pressing research needs.
| Author | : |
| Publisher | : ScholarlyEditions |
| Total Pages | : 53 |
| Release | : 2012-01-09 |
| Genre | : Medical |
| ISBN | : 1464938598 |
Cannabinoid Receptors: Advances in Research and Application: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Cannabinoid Receptors in a concise format. The editors have built Cannabinoid Receptors: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Cannabinoid Receptors in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Cannabinoid Receptors: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
