What made Pope Gregory I “great”? If the Middle Ages had no difficulty recognizing Gregory as one of its most authoritative points of reference, modern readers have not always found this question as easy to answer. As with any great figure, however, there are two sides to Gregory – the historical and the universal. The contributors to this handbook look at Gregory’s “greatness” from both of these angles: what made Gregory stand out among his contemporaries; and what is unique about Gregory’s contribution through his many written works to the development of human thought and described human experience. Contributors include: Jane Baun, Philip Booth, Matthew Dal Santo, Scott DeGregorio, George E. Demacopoulos, Bernard Green, Ann Kuzdale, Stephen Lake, Andrew Louth, Constant J. Mews, John Moorhead, Barbara Müller, Bronwen Neil, Richard M. Pollard, Claire Renkin, Cristina Ricci, and Carole Straw.