Genetic Control of Malaria and Dengue

Genetic Control of Malaria and Dengue
Author: Zach N. Adelman
Publisher: Academic Press
Total Pages: 487
Release: 2015-10-15
Genre: Medical
ISBN: 0128004053

Genetic Control of Malaria and Dengue focuses on the knowledge, technology, regulation and ethics of using genetically modified mosquitoes to interrupt the transmission of important vector-borne diseases including Malaria. It contains coverage of the current state of knowledge of vector-borne diseases and how they are currently controlled; vaccine, drug and insecticide development; various strategies for altering the genome of mosquitoes in beneficial ways; and the regulatory, ethical and social environment concerning these strategies. For more than five decades, the prospect of using genetically-modified mosquitoes to control vector-borne disease transmission has been a purely hypothetical scenario. We simply did not have the technology or basic knowledge to be able to do it. With the explosion of field trials and potential interventions in development, Genetic Control of Malaria and Dengue provides a comprehensive overview of research in genetics, microbiology, virology, and ecology involved in the development and implementation of genetic modification programs for virus and disease control. This book is meant to provide a practical guide to researchers, regulators and the general public about how this technology actually works, how it can be improved, and what is still unknown. - Includes coverage of vectorial capacity, critical to understanding vector-borne disease transmission - Provides a summary of the concepts of both population suppression and population replacement - Contains pivotal coverage of ethical and ecological ramifications of genetics-based control strategies

Mosquitoes of the World

Mosquitoes of the World
Author: Richard C. Wilkerson
Publisher: Johns Hopkins University Press
Total Pages: 1332
Release: 2021-01-19
Genre: Science
ISBN: 1421438143

The most complete reference work on mosquitoes ever produced, Mosquitoes of the World is an unmatched resource for entomologists, public health professionals, epidemiologists, and reference libraries.

Fenner and White's Medical Virology

Fenner and White's Medical Virology
Author: Christopher J. Burrell
Publisher: Academic Press
Total Pages: 605
Release: 2016-11-09
Genre: Science
ISBN: 0123751578

Fenner and White's Medical Virology, Fifth Edition provides an integrated view of related sciences, from cell biology, to medical epidemiology and human social behavior. The perspective represented by this book, that of medical virology as an infectious disease science, is meant to provide a starting point, an anchor, for those who must relate the subject to clinical practice, public health practice, scholarly research, and other endeavors. The book presents detailed exposition on the properties of viruses, how viruses replicate, and how viruses cause disease. These chapters are then followed by an overview of the principles of diagnosis, epidemiology, and how virus infections can be controlled. The first section concludes with a discussion on emergence and attempts to predict the next major public health challenges. These form a guide for delving into the specific diseases of interest to the reader as described in Part II. This lucid and concise, yet comprehensive, text is admirably suited to the needs of not only advanced students of science and medicine, but also postgraduate students, teachers, and research workers in all areas of virology. - Features updated and expanded coverage of pathogenesis and immunity - Contains the latest laboratory diagnostic methods - Provides insights into clinical features of human viral disease, vaccines, chemotherapy, epidemiology, and control

Insect Immunology

Insect Immunology
Author: Nancy E. Beckage
Publisher: Academic Press
Total Pages: 367
Release: 2011-04-28
Genre: Medical
ISBN: 0080556337

This work is the first book-length publication on the topic of insect immunology since 1991, complementing earlier works by offering a fresh perspective on current research. Interactions of host immune systems with both parasites and pathogens are presented in detail, as well as the genomics and proteomics, approaches which have been lacking in other publications. Beckage provides comprehensive coverage of topics important to medical researchers, including Drosophila as a model for studying cellular and humoral immune mechanisms, biochemical mediators of immunity, and insect blood cells and their functions. - Encompasses the most important topics of insect immunology including mechanisms, genes, proteins, evolution and phylogeny - Provides comprehensive coverage of topics important to medical researchers including Drosophila as a model for studying cellular and humoral immune mechanisms, biochemical mediators of immunity, and insect blood cells and their functions - Most up-to-date information published with contributions from international leaders in the field

Mosquitoes, Communities, and Public Health in Texas

Mosquitoes, Communities, and Public Health in Texas
Author: Mustapha Debboun
Publisher: Academic Press
Total Pages: 422
Release: 2019-09-14
Genre: Science
ISBN: 0128145463

Mosquitoes, Communities, and Public Health in Texas focuses on 87 known species of mosquitoes found throughout Texas. It includes information on the ecology, medical and public health importance, and biological diversity of each species. In addition, it provides detailed identification keys for both larval and adult stages of all mosquito genera and species known to occur in Texas, along a review of surveillance and control strategies. The expansion of invasive mosquitoes from other regions (including Mexico), together with climate change occurrences increase the likelihood for an increase in diseases, such as West Nile Virus, Yellow Fever, Dengue, Chikungunya and Zika. This unique work is the first unified reference and resource rich in mosquito information for medical entomologists, mosquito and vector control professionals, pest management professionals, biologists, environmentalists, wildlife professionals, government regulators, instructors of medical entomology and public health professionals who have disease or vector responsibilities, mosquito taxonomists, epidemiologists, entomology students, academia, pest control industry, and libraries, etc., with utility for medical, veterinary and health professionals. - Brings into one volume the previously fragmented or unavailable information on the species of mosquitoes found in Texas and neighboring states of Mexico - Provides a variety of audiences with key data on mosquito biology, distribution and how to identify each - Includes a geographic distribution map, habitat associations, and medical importance on Zika, West Nile virus, Dengue and Chikungunya for each species

The Molecular Biology of Insect Disease Vectors

The Molecular Biology of Insect Disease Vectors
Author: J.M. Crampton
Publisher: Springer Science & Business Media
Total Pages: 590
Release: 2012-12-06
Genre: Science
ISBN: 9400915357

Only one generation ago, entomology was a proudly isolated discipline. In Comstock Hall, the building of the Department of Entomology at Cornell University where I was first introduced to experimental science in the laboratory of Tom Eisner, those of us interested in the chemistry of life felt like interlopers. In the 35 years that have elapsed since then, all of biology has changed, and entomology with it. Arrogant molecular biologists and resentful classical biologists might think that what has happened is a hostile take-over of biology by molecular biology. But they are wrong. More and more we now understand that the events were happier and much more exciting, amounting to a new synthesis. Molecular Biology, which was initially focused on the simplest of organisms, bacteria and viruses, broke out of its confines after the initial fundamental questions were answered - the structure of DNA, the genetic code, the nature of regulatory genes - and, importantly, as its methods became more and more generally applicable. The recombinant DNA revo lution of the 1970s, the development of techniques for sequencing macromolecules, the polymerase chain reaction, new molecular methods of genetic analysis, all brought molecular biology face to face with the infinite complexity and the exuber ant diversity of life. Molecular biology itself stopped being an isolated diScipline, pre occupied with the universal laws of life, and became an approach to addressing fas cinating specific problems from every field of biology.

Malaria

Malaria
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 312
Release: 1991-02-01
Genre: Medical
ISBN: 9780309045278

Malaria is making a dramatic comeback in the world. The disease is the foremost health challenge in Africa south of the Sahara, and people traveling to malarious areas are at increased risk of malaria-related sickness and death. This book examines the prospects for bringing malaria under control, with specific recommendations for U.S. policy, directions for research and program funding, and appropriate roles for federal and international agencies and the medical and public health communities. The volume reports on the current status of malaria research, prevention, and control efforts worldwide. The authors present study results and commentary on the: Nature, clinical manifestations, diagnosis, and epidemiology of malaria. Biology of the malaria parasite and its vector. Prospects for developing malaria vaccines and improved treatments. Economic, social, and behavioral factors in malaria control.

Malaria Control and Elimination Program in the People's Republic of China

Malaria Control and Elimination Program in the People's Republic of China
Author:
Publisher: Academic Press
Total Pages: 383
Release: 2014-12-01
Genre: Medical
ISBN: 0128009195

First published in 1963, Advances in Parasitology contains comprehensive and up-to-date reviews in all areas of interest in contemporary parasitology. Advances in Parasitology includes medical studies of parasites of major influence, such as Plasmodium falciparum and trypanosomes. The series also contains reviews of more traditional areas, such as zoology, taxonomy, and life history, which shape current thinking and applications. The 2012 impact factor is 3.778. - Informs and updates on all the latest developments in the field - Contributions from leading authorities and industry experts

Genetics and Evolution of Infectious Diseases

Genetics and Evolution of Infectious Diseases
Author: Michel Tibayrenc
Publisher: Elsevier
Total Pages: 1002
Release: 2024-07-19
Genre: Medical
ISBN: 0443288194

Genetics and Evolution of Infectious Diseases, Third Edition discusses the evolving field of infectious diseases and their continued impact on the health of populations, especially in resource-limited areas of the world where they must confront the dual burden of death and disability due to infectious and chronic illnesses. Although substantial gains have been made in public health interventions for the treatment, prevention, and control of infectious diseases, in recent decades the world has witnessed the emergence of the human immunodeficiency virus (HIV) and the COVID-19 pandemic, increasing antimicrobial resistance, and the emergence of many new bacterial, fungal, parasitic, and viral pathogens. Fully updated and revised, this new edition presents the consequences of such diseases, the evolution of infectious diseases, the genetics of host-pathogen relationship, and the control and prevention strategies that are, or can be, developed. This book offers valuable information to biomedical researchers, clinicians, public health practitioners, decisions-makers, and students and postgraduates studying infectious diseases, microbiology, medicine, and public health that is relevant to the control and prevention of neglected and emerging worldwide diseases. - Takes an integrated approach to infectious diseases - Provides the latest developments in the field of infectious diseases - Focuses on the contribution of evolutionary and genomic studies for the study and control of transmissible diseases - Includes updated and revised contributions from leading authorities, along with six new chapters

Biodiversity of Malaria in the World

Biodiversity of Malaria in the World
Author: Jean Mouchet
Publisher: John Libbey Eurotext
Total Pages: 468
Release: 2008
Genre: Medical
ISBN:

One million dead a Wear, 500 million with the disease, 2.5 billion people at risk : this is the malaria balance sheet in 2007. The distribution and seriousness of the disease depend on the pathogens and vectors involved, as welt as environmental conditions. Of the four parasites (Plasmodium), only P. falciparum kilts although the other three cause debilitating disease with regular relapses and recrudescence. More than fifty species of Anopheles can fulfil the vector rote which is essential in transmission of the parasite between human beings. Climatic factors (temperature and rainfall), the environment and biogeographical particularities dictate the distribution of anopheline species and determine transmission rates. This is why it makes sense to tank about the biodiversity of malaria. Today, more than 90% of deaths from malaria occur in Tropical Africa which is home to only 10% of humanity. Every 30 seconds a child dies from malaria. This continent harbours the most effective vectors (An. gambiae and An. funestus, in particular) and the climate is highly conducive to transmission of the disease. Severe malaria is also seen in forest foci in Southeast Asia, Papua-New Guinea and the Amazon. In the rest of the tropical and subtropical world, P. vivax and/or P malariae cause less severe disease.