Biological Activity of Natural Products

Biological Activity of Natural Products
Author: Jaroslava Švarc-Gajić
Publisher: Nova Science Publishers
Total Pages: 0
Release: 2013
Genre: Health & Fitness
ISBN: 9781628089264

Many thousands of years ago, humans were introduced to the toxicants of minerals and plants of microbial origin, and since that time, natural bioactive compounds have been used in traditional medicine for treating different health conditions, but also as aphrodisiacs and as a means of suicide or murder. Modern medicine acknowledges natural bioactive compounds as valuable medicinal sources for both diagnostic and curative purposes. Natural compounds serve as templates for the production of new drugs with improved pharmacological properties. This book explains the term bioactivity and deals with the bioactive compounds of plants, animals, microbial and marine origin. Their use by traditional medicinal approach, as well as by modern medicine is further elaborated. Both beneficial and toxic properties of different chemical classes, including alkaloids, peptides, terpenoids, bioactive amines etc., are described. Their isolation at the industrial scale is presented through several technological processes which are explained in detail for several compound classes. The research explains how natural sources can be exploited my modern and traditional medicine, and presents the risks and benefits associated with their use. In addition, a new approach to studying bioactivity, that includes computational modelling and softwares for in silico description and prediction, is explained. A chemometric approach to studying bioactivity is demonstrated through several models given for some natural bioactive compounds and their derivatives.

Studies in Natural Products Chemistry

Studies in Natural Products Chemistry
Author: Atta-ur- Rahman
Publisher: Elsevier
Total Pages: 422
Release: 2012-09-06
Genre: Medical
ISBN: 0444595147

Natural products play an integral and ongoing role in promoting numerous aspects of scientific advancement, and many aspects of basic research programs are intimately related to natural products. With articles written by leading authorities in their respective fields of research, Studies in Natural Products Chemistry, Volume 37 presents current frontiers and future guidelines for research based on important discoveries made in the field of bioactive natural products. It is a valuable source for researchers and engineers working in natural products and medicinal chemistry. Describes the chemistry of bioactive natural products Contains contributions by leading authorities in the field A valuable source for researchers and engineers working in natural product and medicinal chemistry

Bioactive Natural Products

Bioactive Natural Products
Author: Goutam Brahmachari
Publisher: John Wiley & Sons
Total Pages: 544
Release: 2015-03-23
Genre: Science
ISBN: 3527337946

Ein multidisziplinärer Überblick über die aktuellen Themen und Zukunftstrends in der Erforschung von Naturstoffen mit Schwerpunkt auf pharmazeutischen und medizinischen Anwendungen.

Biological and Pharmacological Activity of Plant Natural Compounds

Biological and Pharmacological Activity of Plant Natural Compounds
Author: Raffaele Pezzani
Publisher: MDPI
Total Pages: 296
Release: 2021-03-12
Genre: Medical
ISBN: 3036503048

Phytotherapy is probably the oldest form of medicine; however, it represents a new therapeutic tool for healthcare workers. Indeed plants are an infinite source of novel molecules, with countless possible combinations. This collection of articles (a Special Issue from Molecules) brings together the most up-to-date studies on the use of plant-derived compounds, ranging from their anti-inflammatory, antioxidant, and anticancer effects to the revision of the prominent literature.

Bioactive Natural Products

Bioactive Natural Products
Author: Goutam Brahmachari
Publisher: World Scientific
Total Pages: 695
Release: 2012
Genre: Science
ISBN: 9814335371

Bioactive natural products are a rich source of novel therapeutics. Thus, the search for bioactive molecules from nature continues to play an important role in fashioning new medicinal agents. This volume, which comprises sixteen chapters written by active researchers and leading experts in natural products chemistry, brings together an overview of current discoveries in this remarkable field. It also provides information on the industrial application of natural products for medicinal purposes. This book will serve as a valuable resource for researchers to predict promising leads for developing pharmaceuticals to treat various ailments and disease manifestations.

Natural Products

Natural Products
Author: J. Mann
Publisher: Longman Publishing Group
Total Pages: 502
Release: 1994
Genre: Science
ISBN:

An account of the structure, chemistry, biosynthesis, and biological activity of most types of organic compounds, with each chapter devoted to classes of compounds, such as carbohydrates, nucleotides and polynucleotides, fatty acids, terpenoids, phenolics, and alkaloids. Includes numerous bandw diagrams. An excellent complement to a standard text on basic organic chemistry. For senior undergraduates and graduate students of organic and medicinal chemistry, biochemistry, pharmacy, and pharmacology. Annotation copyright by Book News, Inc., Portland, OR

Studies in Natural Products Chemistry

Studies in Natural Products Chemistry
Author: Atta-ur Rahman
Publisher: Elsevier
Total Pages: 460
Release: 2020-06-24
Genre: Science
ISBN: 0128179066

Studies in Natural Products Chemistry: Bioactive Natural Products, Volume 65, the latest in a series that covers the synthesis or testing and recording of the medicinal properties of natural products, provides cutting-edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products. Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to quickly isolate and determine the structures and biological activity of natural products. This has opened up exciting opportunities in the field of new drug development to the pharmaceutical industry. - Focuses on the chemistry of bioactive natural products - Contains contributions by leading authorities in the field - Presents sources of new pharmacophores

New Natural Products and Plant Drugs with Pharmacological, Biological or Therapeutical Activity

New Natural Products and Plant Drugs with Pharmacological, Biological or Therapeutical Activity
Author: H.K. Wagner
Publisher: Springer Science & Business Media
Total Pages: 299
Release: 2012-12-06
Genre: Medical
ISBN: 3642666825

The fact that, of the approximately 600,000 plant species existing on the earth, only some 5 % have been specifically investigated chemically or pharmacologi cally, is a challenge to chemists spezializing in na tural substances and to pharmacologists. In view of the limited number of research capacities and the ever diminishing financial means, this challenge can only be met if, together with an improvement and refinement of methods of analysis, medicinal plant research is carried out on a broader interdisciplinary basis, with comparable, scientifically recognized screening methods, and if it is better coordinated, with greater use of modern documentation means. It is thus necessary in the future to concentrate specifically on projects leading to the development of new medicinal prepara tions. The plenary lectures hold in the present symposium of the 1st International Congress for Research on Medi cinal Plants reflect these efforts and tendencies. At the same time they provide a survey of some of the fields of medicinal plant research which are at present most actual and most intensively researched. They range from plant screening, isolation and structure eluci dation of new principles, to the therapeutical opti mization of a natural product. The lectures given at this congress show clearly the necessity, in addition to national phytochemical so cieties, for a central international organisation, in which all active medicinal plant researchers in the world are included. Their aim should be to provide the impulse for more optimal, rational research, aimed at the solution of specific projects.

Biological Activity and Applications of Natural Compounds

Biological Activity and Applications of Natural Compounds
Author: Ana M. L Seca
Publisher:
Total Pages: 206
Release: 2020
Genre:
ISBN: 9783039366187

Nature represents an amazing source of inspiration, since it produces a great diversity of natural compounds selected by evolution, which exhibit multiple biological activities and applications. A large and very active research field is dedicated to identifying biosynthesized compounds, to improve/develop new methodologies, to produce/reuse natural compounds, and to assess their potential for pharmaceutical, cosmetic and food industries, among others, and additionally, to understand their mechanism of action. This book is dedicated to presenting the most recent results on the development of natural compounds' applications. Ten original research works, organized by applications, and two reviews are included. Each of them contributes to the knowledge advance, insofar as they present new applications for known products, new methodologies to obtain new products, or the evaluation of a given application, with the applications related to health promotion being the most frequently considered. These works are significant contributions and reinforce the dynamic field of natural products' applications.

Plant-derived Natural Products

Plant-derived Natural Products
Author: Anne E. Osbourn
Publisher: Springer Science & Business Media
Total Pages: 588
Release: 2009-07-07
Genre: Science
ISBN: 0387854983

Plants produce a huge array of natural products (secondary metabolites). These compounds have important ecological functions, providing protection against attack by herbivores and microbes and serving as attractants for pollinators and seed-dispersing agents. They may also contribute to competition and invasiveness by suppressing the growth of neighboring plant species (a phenomenon known as allelopathy). Humans exploit natural products as sources of drugs, flavoring agents, fragrances and for a wide range of other applications. Rapid progress has been made in recent years in understanding natural product synthesis, regulation and function and the evolution of metabolic diversity. It is timely to bring this information together with contemporary advances in chemistry, plant biology, ecology, agronomy and human health to provide a comprehensive guide to plant-derived natural products. Plant-derived natural products: synthesis, function and application provides an informative and accessible overview of the different facets of the field, ranging from an introduction to the different classes of natural products through developments in natural product chemistry and biology to ecological interactions and the significance of plant-derived natural products for humans. In the final section of the book a series of chapters on new trends covers metabolic engineering, genome-wide approaches, the metabolic consequences of genetic modification, developments in traditional medicines and nutraceuticals, natural products as leads for drug discovery and novel non-food crops.