Biochemistry And The Central Nervous System
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Biochemistry of Characterised Neurons
| Author | : Neville N. Osborne |
| Publisher | : Elsevier |
| Total Pages | : 374 |
| Release | : 2013-10-22 |
| Genre | : Science |
| ISBN | : 1483145530 |
Biochemistry of Characterised Neurons provides a report on the progress made in the analysis of the biology of specific neurons in the central nervous system. This book emphasizes the biochemical, morphological, and functional aspects of characterized neurons, including ways and sophisticated techniques of isolating them. This publication is divided into 11 chapters. The first chapter evaluates the relevance of working with single neurons. Chapters 2 to 6 discuss specific, characterized, invertebrate neurons containing one of the putative neurotransmitter substances. Chapter 7 deals with the biochemistry of a unique vertebrate (Torpedo) cholinergic system that enables pure cholinergic neuronal cell bodies and endings to be analyzed separately. The sensitive radiochemical procedures used to analyze transmitter substances and transmitter enzymes, and how they can be adapted to map the distribution of transmitters in individual neurons of Aplysia, are discussed in Chapter 8. Chapter 9 describes methods for the analysis of specific cells in the retina, while Chapters 10 and 11 focus on the analysis of proteins within defined neurons. This text is beneficial to biochemists and students interested in analyzing neurons.
Medical Biochemistry: The Big Picture
| Author | : Lee W. Janson |
| Publisher | : McGraw Hill Professional |
| Total Pages | : 431 |
| Release | : 2012-03-25 |
| Genre | : Medical |
| ISBN | : 0071637923 |
Get the BIG PICTURE of Medical Biochemistry – and target what you really need to know to ace the course exams and the USMLE Step 1 300 FULL-COLOR ILLUSTRATIONS Medical Biochemistry: The Big Picture is a unique biochemistry review that focuses on the medically applicable concepts and techniques that form the underpinnings of the diagnosis, prognosis, and treatment of medical conditions. Those preparing for the USMLE, residents, as well as clinicians who desire a better understanding of the biochemistry behind a particular pathology will find this book to be an essential reference. Featuring succinct, to-the-point text, more than 300 full-color illustrations, and a variety of learning aids, Medical Biochemistry: The Big Picture is designed to make complex concepts understandable in the shortest amount of time possible. This full-color combination text and atlas features: Progressive chapters that allow you to build upon what you’ve learned in a logical, effective manner Chapter Overviews that orient you to the important concepts covered in that chapter Numerous tables and illustrations that clarify and encapsulate the text Sidebars covering a particular disease or treatment add clinical relevance to topic discussed Essay-type review questions at the end of each chapter allow you to assess your comprehension of the major topics USMLE-style review questions at the end of each section Three appendices, including examples of biochemically based diseases, a review of basic biochemical techniques, and a review of organic chemistry/biochemistry
Magnesium in the Central Nervous System
| Author | : Robert Vink |
| Publisher | : University of Adelaide Press |
| Total Pages | : 354 |
| Release | : 2011 |
| Genre | : Medical |
| ISBN | : 0987073052 |
The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.
Scientific Foundations of Clinical Biochemistry
| Author | : David Llewelyn Williams |
| Publisher | : Year Book Medical Publishers, Incorporated |
| Total Pages | : 512 |
| Release | : 1978 |
| Genre | : Science |
| ISBN | : |
Central Nervous System Diseases and Inflammation
| Author | : Thomas E. Lane |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 321 |
| Release | : 2007-12-24 |
| Genre | : Medical |
| ISBN | : 0387738940 |
Edited and authored by top names in the field, this book provides a succinct reference on inflammatory central nervous system disease. It focuses on current areas of investigation in the fields of neuroimmunology, virology, pharmacology, and disease. Sections focus on specific categories of diseases, examining the pharmacological, virological, and immunological effects of and on the disease. This book’s unique organization provides a concise overview of inflammatory CNS disease.
The Wiley Handbook of Evolutionary Neuroscience
| Author | : Stephen V. Shepherd |
| Publisher | : John Wiley & Sons |
| Total Pages | : 602 |
| Release | : 2017-01-30 |
| Genre | : Psychology |
| ISBN | : 1119994691 |
Comprehensive and authoritative, The Wiley Handbook of Evolutionary Neuroscience unifies the diverse strands of an interdisciplinary field exploring the evolution of brains and cognition. A comprehensive reference that unifies the diverse interests and approaches associated with the neuroscientific study of brain evolution and the emergence of cognition Tackles some of the biggest questions in neuroscience including what brains are for, what factors constrain their biological development, and how they evolve and interact Provides a broad and balanced view of the subject, reviewing both vertebrate and invertebrate anatomy and emphasizing their shared origins and mechanisms Features contributions from highly respected scholars in their fields
Functional Neurobiology of Aging
| Author | : Patrick R. Hof |
| Publisher | : Elsevier |
| Total Pages | : 989 |
| Release | : 2001-01-11 |
| Genre | : Medical |
| ISBN | : 008052558X |
Some well-known age-related neurological diseases include Parkinson's disease, Alzheimer's disease, deafness, and blindness. Even more common are the problems of aging which are not due to disease but to more subtle impairments in neurobiological systems, including impairments in vision, memory loss, muscle weakening, and loss of reproductive functions, changes in body weight, and sleeplessness. As the average age of our society increases, diseases of aging continue to become more common, and conditions associated with aging need more attention by doctors and researchers. In 1991, patients over the age of 65 saw their doctors an average of eight times per year. Research funding is provided by the Neuroscience and Neuropsychology of Aging (NNA) Program, which is run by the National Institute on Aging. This book offers a comprehensive overview of all topics related to functional impairments which are related to the aging brain and nervous system. It is organized according to four general functions: movement, senses, memory, and neuroendocrine regulation. Written by the leading researchers in the field, this comprehensive work addresses both impairments associated with diseases and not associated with diseases, making it easier to understand the mechanisms involved. Functional Neurobiology of Aging is an important reference for professionals and students involved in aging research, as well as physicians who need to recognize and understand age-related impairments. - Organized by function, making it easy to find and understand the material - Addresses impairments both associated with diseases and not associated with diseases - Written by leading researchers in the field - Most comprehensive source of information on the neurobiology of aging
Biochemistry of Copper
| Author | : Maria C. Linder |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 534 |
| Release | : 2013-11-21 |
| Genre | : Science |
| ISBN | : 1475794320 |
Copper has long been known as essential to living systems, in part through its fundamental role in electron transport and respiration. Over the years into the present, its involvement in an ever increasing number of processes in all kinds of organisms has become apparent, and new and exciting vistas of its roles in such areas as the central nervous system, and in humoral functions, are appearing on the horizon. Although the biochemistry of this element has not been studied nearly as much as that of many others, a for midable amount of work has been carried out. It has thus been a challenge to produce a summary of what has been found that provides both breadth and depth. My goal has been to try to be as comprehensive as possible, within some limitations. I have tried to provide basic information and basic data that should continue to be useful for a long time. The goal has also been to interpret where we currently stand in our knowledge of the structure, function, regulation, and metabolism of Cu-dependent processes and sub stances, especially proteins. Thus, I have tried to make this a source book for historic as well as current information on all aspects of copper bio chemistry, and a summary of our current knowledge of copper-dependent proteins and processes. Most of the research on copper has been carried out on vertebrates, especially mammals. This has played a role in the organization of the book.
Water Soluble Vitamins
| Author | : Olaf Stanger |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 388 |
| Release | : 2011-11-27 |
| Genre | : Medical |
| ISBN | : 9400721994 |
The discovery of vitamins in the early 1900s, their later chemical characterization and the clarification of pivotal metabolic functions are sequential aspects of a brilliant chapter in the history of modern nutritional sciences and medicine. The name, derived from “vital-amines”, indicates their elementary metabolic key functions in human metabolism. Vitamins are truly families of compounds, which include precursors and various free and bound forms, all with individual roles in metabolism and function. A more recent approach therefore searches for the components, the understanding of their roles in physiology and pathology as well as looking for novel pharmacological applications. When used properly, vitamins are, indeed, “magical” substances. Due to their efficacy, they should therefore be regarded as drugs with effects and side effects to be weighted against each other. Today, it is not the previously fatal deficiency-associated diseases that are in the focus of interest, but rather the relation of suboptimal vitamin bioavailability to chronic disease. This is complicated by genetic susceptibility, lifestyle, and the presence or absence of health-compromising habits, such as smoking. In turn, the development and application of new and more sensitive and specific assays further enable us to look more closely into the many functions of vitamins. Water soluble vitamins are complex molecular structures and even today, many areas in vitamin biochemistry are not yet fully understood. Novel effects and functions of vitamins remain and continue to be discovered. This book presents most recent research results and fascinating new knowledge on the role and effects of the water soluble vitamins in man. Some of the most distinguished chemists, biochemists, biologists and clinicians have contributed valuable chapters sharing unexpected novel insights into the biochemistry, (epi)genetics, metabolism, and function of water soluble vitamins, with their potential for clinical applications. Thus, physicians, clinicians, scientists, researchers, epidemiologists. nutritional specialists and health professionals alike will find stimulating and fascinating new insight in the many roles that water soluble vitamins play in human health and disease.
