Biocatalysis Biochemical Fundamentals And Applications
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Author | : Peter Grunwald |
Publisher | : World Scientific Publishing Company |
Total Pages | : 1052 |
Release | : 2009-03-02 |
Genre | : Science |
ISBN | : 1848168217 |
The book covers the fundamentals of the field of biocatalysis that are not treated in such detail (or even not at all) in existing biocatalysis books or biochemistry textbooks. It of course does not substitute existing biochemistry textbooks but will serve a suitable supplement as it discusses biochemical fundamentals in connection with the respective topics.With focus on the interdisciplinary nature of biocatalysis, the book contains many aspects of fundamental organic chemistry and some of inorganic chemistry as well, which should make it interesting not only for biochemistry but also for chemistry students. An important theme being emphasized in the book is that applied biocatalysis is one of the main prerequisites for a sustainable development.The topics covered ranges from basic enzyme chemistry (biosynthesis, structure, properties, interaction forces, kinetics) to a detailed description of catalytic mechanisms. It covers the fundamentals of the different enzyme classes together with their applications in native and in immobilized state or in the form of whole cells in aqueous as well as non-conventional media. Topics such as catalytic antibodies, nucleic acid catalysts, non-ribosomal peptide synthesis, evolutionary methods, and the design of cells are also included.
Author | : Peter Grunwald |
Publisher | : World Scientific Publishing Company |
Total Pages | : 1314 |
Release | : 2017-08-04 |
Genre | : Science |
ISBN | : 1783269103 |
In this Completely Revised and Extended Edition with a significantly enhanced content, all Chapters have been updated considering relevant literature and recent developments until 2016 together with application oriented examples with a focus on Industrial Biocatalysis. Newly treated topics comprise among others systems metabolic engineering approaches, metagenome screening, new tools for pathway engineering, and de-novo computational design as actual research areas in biocatalysis. Information about different aspects of RNA technologies, and completely new Chapters on 'Fluorescent Proteins' and 'Biocatalysis and Nanotechnology' are also included.
Author | : Daniela Gamenara |
Publisher | : John Wiley & Sons |
Total Pages | : 681 |
Release | : 2012-09-18 |
Genre | : Science |
ISBN | : 1118409329 |
Paves the way for new industrial applications using redox biocatalysis Increasingly, researchers rely on the use of enzymes to perform redox processes as they search for novel industrial synthetic routes. In order to support and advance their investigations, this book provides a comprehensive and current overview of the use of redox enzymes and enzyme-mediated oxidative processes, with an emphasis on the role of redox enzymes in chemical transformations. The authors examine the full range of topics in the field, from basic principles to new and emerging research and applications. Moreover, they explore everything from laboratory-scale procedures to industrial manufacturing. Redox Biocatalysis begins with a discussion of the biochemical features of redox enzymes as well as cofactors and cofactor regeneration methods. Next, the authors present a variety of topics and materials to the research and development of full-scale industrial applications, including: Biocatalytic applications of redox enzymes such as dehydrogenases, oxygenases, oxidases, and peroxidases Enzyme-mediated oxidative processes based on biocatalytic promiscuity All the steps from enzyme discovery to robust industrial processes, including directed evolution, high-throughput screening, and medium engineering Case studies tracing the development of industrial applications using biocatalytic redox reactions Each chapter ends with concluding remarks, underscoring the key scientific principles and processes. Extensive references serve as a gateway to the growing body of research in the field. Researchers in both academia and industry will find this book an indispensable reference for redox biotransformations, guiding them from underlying core principles to new discoveries and emerging industrial applications.
Author | : Andreas S. Bommarius |
Publisher | : John Wiley & Sons |
Total Pages | : 648 |
Release | : 2004-03-12 |
Genre | : Science |
ISBN | : 9783527303441 |
Mittlerweile nutzen alle so genannten Life Sciences (z.B. Pharma- und Ernährungswissenschaften) die Möglichkeiten der Biokatalyse. Auch das Interesse der verarbeitenden Industrie an umweltverträglichen Prozessen wächst stetig. Da kommt es nicht von ungefähr, dass die Erforschung von Biokatalysatoren weiter vorangeschritten ist als die anderer Katalysatorentypen. Biocatalysis gibt einen aktuellen Überblick über das Wissen in diesem Gebiet, von den theoretischen Grundlagen bis hin zu Anwendungen und einem Ausblick in die Zukunft. Bommarius und Riebel geht es in ihrem Buch nicht nur um Reaktionen, Produkte und Prozesse im Zusammenhang mit biologischen Katalysen und Katalysatoren. Sie erläutern auch den Prozess der Entwicklung und Verbesserung von Biokatalysatoren. Dabei schenken sie den Bereichen Chemie, Biologie und Biotechnologie die gleiche Aufmerksamkeit, so dass ihr Buch für Praktiker und Studenten aus allen drei Bereichen von Nutzen ist. Biocatalysis gliedert sich in die Abschnitte "Grundlagen und Basis-Tools", "Fortgeschrittene Tools" sowie "Anwendungen". Im ersten Teil gehen die Autoren unter anderem auf die Stellung der Biokatalyse in der Biotechnologie ein, beschreiben Isolierung und Vorbereitung von Mikroorganismen und stellen molekularbiologische Tools für die Biokatalyse vor. Teil II beschreibt zum Beispiel die Enzymherstellung sowie Methoden zur Protein-Untersuchung und beschäftigt sich mit pharmazeutischen Anwendungen der Biokatalyse und der Bioinformatik. Im letzten Abschnitt geht es schließlich um künstliche Enzyme, das Design biokatalytischer Prozesse und um neue Möglichkeiten, die sich durch den Einsatz der Bioinformatik eröffnen.
Author | : Peter Grunwald |
Publisher | : |
Total Pages | : 1052 |
Release | : 2008 |
Genre | : Electronic books |
ISBN | : 9781848162310 |
Author | : Martine Poux |
Publisher | : CRC Press |
Total Pages | : 470 |
Release | : 2015-06-02 |
Genre | : Science |
ISBN | : 1482208180 |
This book has been edited by Martine Poux, Patrick Cognet and Christophe Gourdon from the Laboratoire de Genie Chimique/ENSIACET, Toulouse. It presents an ensemble of methods and new chemical engineering routes that can be integrated in industrial processing for safer, more flexible, economical, and ecological production processes in the context of
Author | : Peter Grunwald |
Publisher | : |
Total Pages | : 1314 |
Release | : 2017 |
Genre | : Electronic books |
ISBN | : 9781783269099 |
Author | : Peter Grunwald |
Publisher | : Imperial College Press |
Total Pages | : 1052 |
Release | : 2009 |
Genre | : Science |
ISBN | : 1860947441 |
The book covers the fundamentals of the field of biocatalysis that are not treated in such detail (or even not at all) in existing biocatalysis books or biochemistry textbooks. It of course does not substitute existing biochemistry textbooks but will serve a suitable supplement as it discusses biochemical fundamentals in connection with the respective topics.With focus on the interdisciplinary nature of biocatalysis, the book contains many aspects of fundamental organic chemistry and some of inorganic chemistry as well, which should make it interesting not only for biochemistry but also for chemistry students. An important theme being emphasized in the book is that applied biocatalysis is one of the main prerequisites for a sustainable development.The topics covered ranges from basic enzyme chemistry (biosynthesis, structure, properties, interaction forces, kinetics) to a detailed description of catalytic mechanisms. It covers the fundamentals of the different enzyme classes together with their applications in native and in immobilized state or in the form of whole cells in aqueous as well as non-conventional media. Topics such as catalytic antibodies, nucleic acid catalysts, non-ribosomal peptide synthesis, evolutionary methods, and the design of cells are also included.
Author | : Klaus Buchholz |
Publisher | : John Wiley & Sons |
Total Pages | : 609 |
Release | : 2012-12-21 |
Genre | : Science |
ISBN | : 3527672001 |
This second edition of a bestselling textbook offers an instructive and comprehensive overview of our current knowledge of biocatalysis and enzyme technology. The book now contains about 40% more printed content. Three chapters are completely new, while the others have been thoroughly updated, and a section with problems and solutions as well as new case studies have been added. Following an introduction to the history of enzyme applications, the text goes on to cover in depth enzyme mechanisms and kinetics, production, recovery, characterization and design by protein engineering. The authors treat a broad range of applications of soluble and immobilized biocatalysts, including wholecell systems, the use of non-aqueous reaction systems, applications in organic synthesis, bioreactor design and reaction engineering. Methods to estimate the sustainability, important internet resources and their evaluation, and legislation concerning the use of biocatalysts are also covered.
Author | : Guillermo R. Castro |
Publisher | : Elsevier |
Total Pages | : 755 |
Release | : 2021-10-12 |
Genre | : Technology & Engineering |
ISBN | : 0128244372 |
Nanomaterials for Biocatalysis explains the fundamental design concepts and emerging applications of nanoscale biocatalysts, such as bioconversions, bioelectronics, biosensors, biocomputing and therapeutic applications. Nano-biocatalysts refers to the incorporation of enzymes into nanomaterials. These enzyme-enhanced nanocarriers have many advantages, including low mass transfer limitation, high enzyme capacity, better stabilization, and the formation of single-enzyme nanoparticles. Smart nanocontainers have been developed for the smart release of their embedded active substances. These smart releases can be obtained by using smart coatings as their outer nanoshells. In addition, these nanocontainers could protect the enzymes from chemical or metabolic alterations on their delivering pathways towards the target. This is an important reference source for materials scientists and chemical engineers who want to know more about how nanomaterials are being used for biocatalysis applications. - Explains the major fabrication techniques and applications of nanobiocatalysts - Shows how nanobiocatalysts are used in a variety of environmental and biomedical sectors - Assesses the major challenges associated with the widespread manufacture of nanobiocatalysts