Beta-Cell Fate: From Gene Circuits to Disease Mechanisms
| Author | : Simona Chera |
| Publisher | : Frontiers Media SA |
| Total Pages | : 124 |
| Release | : 2022-03-16 |
| Genre | : Science |
| ISBN | : 2889747123 |
Beta Cell Fate From Gene Circuits To Disease Mechanisms
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Molecular Biology of B Cells
| Author | : Tasuku Honjo |
| Publisher | : Academic Press |
| Total Pages | : 0 |
| Release | : 2014-12-22 |
| Genre | : Science |
| ISBN | : 9780123979339 |
Molecular Biology of B Cells, Second Edition is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All of these developmental and stimulatory processes are described in molecular, immunological, and genetic terms to give a clear understanding of complex phenotypes. Molecular Biology of B Cells, Second Edition offers an integrated view of all aspects of B cells to produce a normal immune response as a constant, and the molecular basis of numerous diseases due to B cell abnormality. The new edition continues its success with updated research on microRNAs in B cell development and immunity, new developments in understanding lymphoma biology, and therapeutic targeting of B cells for clinical application. With updated research and continued comprehensive coverage of all aspects of B cell biology, Molecular Biology of B Cells, Second Edition is the definitive resource, vital for researchers across molecular biology, immunology and genetics.
Stem Cell Bioengineering
| Author | : Biju Parekkadan |
| Publisher | : Artech House |
| Total Pages | : 223 |
| Release | : 2009 |
| Genre | : Medical |
| ISBN | : 1596934034 |
In stem cell research there are several key methods that, once mastered, can be extremely powerful. These methods enable you to rigorously test hypotheses, compare results to "gold standards," and may even spur improvements to existing protocols. This book describes numerous methods to derive, manipulate, target, and prepare stem cells for clinical use. The methods described here help you derive and test human embryonic stem cells, analyze bone marrow stem cell function in vitro and in vivo, image a stem cell transplant, cryopreserve stem cells and differentiate stem cells using microscale tec.
Mechanisms of Insulin Action
| Author | : Alan R. Saltiel |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 223 |
| Release | : 2007-10-05 |
| Genre | : Medical |
| ISBN | : 0387722041 |
More than 18 million people in the United States have diabetes mellitus, and about 90% of these have the type 2 form of the disease. This book attempts to dissect the complexity of the molecular mechanisms of insulin action with a special emphasis on those features of the system that are subject to alteration in type 2 diabetes and other insulin resistant states. It explores insulin action at the most basic levels, through complex systems.
Stem Cells and Regenerative Medicine
| Author | : Walter C. Low |
| Publisher | : World Scientific |
| Total Pages | : 571 |
| Release | : 2008 |
| Genre | : Medical |
| ISBN | : 9812775773 |
The commercialization of biotechnology has resulted in an intensive search for new biological resources for the purposes of increasing food productivity, medicinal applications, energy production, and various other applications. Although biotechnology has produced many benefits for humanity, the exploitation of the planet's natural resources has also resulted in some undesirable consequences such as diminished species biodiversity, climate change, environmental contamination, and intellectual property right and patent concerns.This book discusses the role of biological, ecological, environmental, ethical, and economic issues in the interaction between biotechnology and biodiversity, using different contexts. No other book has discussed all of these issues in a comprehensive manner. Of special interest is their impact when biotechnology is shared between developed and developing countries, and the lack of recognition of the rights of indigenous populations and traditional farmers in developing countries by large multinational corporations.
New Cerebrospinal Fluid Research to Uncover Mechanisms Driving Neurological and Psychiatric Diseases
| Author | : Thomas Skripuletz |
| Publisher | : Frontiers Media SA |
| Total Pages | : 169 |
| Release | : 2020-12-18 |
| Genre | : Medical |
| ISBN | : 2889661806 |
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Genomic Regulatory Systems
| Author | : Eric H. Davidson |
| Publisher | : Elsevier |
| Total Pages | : 274 |
| Release | : 2001-01-24 |
| Genre | : Science |
| ISBN | : 0080525598 |
The interaction between biology and evolution has been the subject of great interest in recent years. Because evolution is such a highly debated topic, a biologically oriented discussion will appeal not only to scientists and biologists but also to the interested lay person. This topic will always be a subject of controversy and therefore any breaking information regarding it is of great interest.The author is a recognized expert in the field of developmental biology and has been instrumental in elucidating the relationship between biology and evolution. The study of evolution is of interest to many different kinds of people and Genomic Regulatory Systems: In Development and Evolution is written at a level that is very easy to read and understand even for the nonscientist. * Contents Include* Regulatory Hardwiring: A Brief Overview of the Genomic Control Apparatus and Its Causal Role in Development and Evolution * Inside the Cis-Regulatory Module: Control Logic and How the Regulatory Environment Is Transduced into Spatial Patterns of Gene Expression* Regulation of Direct Cell-Type Specification in Early Development* The Secret of the Bilaterians: Abstract Regulatory Design in Building Adult Body Parts* Changes That Make New Forms: Gene Regulatory Systems and the Evolution of Body Plans
Computational Immunology
| Author | : Shyamasree Ghosh |
| Publisher | : CRC Press |
| Total Pages | : 181 |
| Release | : 2020-01-31 |
| Genre | : Medical |
| ISBN | : 1351023489 |
Computational Immunology: Applications focuses on different mathematical models, statistical tools, techniques, and computational modelling that helps in understanding complex phenomena of the immune system and its biological functions. The book also focuses on the latest developments in computational biology in designing of drugs, targets, biomarkers for early detection and prognosis of a disease. It highlights the applications of computational methods in deciphering the complex processes of the immune system and its role in health and disease. This book discusses the most essential topics, including Next generation sequencing (NGS) and computational immunology Computational modelling and biology of diseases Drug designing Computation and identification of biomarkers Application in organ transplantation Application in disease detection and therapy Computational methods and applications in understanding of the invertebrate immune system S Ghosh is MSc, PhD, PGDHE, PGDBI, is PhD from IICB, CSIR, Kolkata, awarded the prestigious National Scholarship from the Government of India. She has worked and published extensively in glycobiology, sialic acids, immunology, stem cells and nanotechnology. She has authored several publications that include books and encyclopedia chapters in reputed journals and books.
Regulation of microRNAs
| Author | : Helge Großhans |
| Publisher | : Springer |
| Total Pages | : 160 |
| Release | : 2011-08-25 |
| Genre | : Science |
| ISBN | : 9781441978240 |
Given this pervasiveness and importance of miRNA-mediated gene regulation, it should come as little surprise that miRNAs themselves are also highly regulated. However, the recent explosion of knowledge on this topic has been remarkable, providing a primary motivation for publication of this book. As miRNAs are transcribed by RNA polymerase II, the enzyme that also generates mRNAs, it was perhaps not unexpected that miRNA transcription would be subject to regulation, and we have willfully mitted this aspect from this monograph. However, what has been unexpected is the extent of post-transcriptional regulation of miRNAs that is illustrated in this book.
Circuit Mechanisms of Neurodegenerative Diseases
| Author | : Sabine Liebscher |
| Publisher | : Frontiers Media SA |
| Total Pages | : 165 |
| Release | : 2020-12-18 |
| Genre | : Science |
| ISBN | : 2889661768 |
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
