Behavioral Pharmacology Of The Cholinergic System
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| Author | : Mohammed Shoaib |
| Publisher | : Springer Nature |
| Total Pages | : 245 |
| Release | : 2020-08-29 |
| Genre | : Medical |
| ISBN | : 3030560139 |
The molecular genetics of the cholinergic system including both muscarinic and nicotinic acetylcholine receptors, cholinesterases, acetylcholine synthesis and release have provided significant insights into potential targeting for pharmacological intervention. Cholinergic drugs are being used or evaluated for the treatment of diseases. Thus, this volume aims to broaden our understanding of the current state of cholinergic mechanisms to enable implementation of novel approaches for the development of more effective treatments.
| Author | : Edward D Levin |
| Publisher | : CRC Press |
| Total Pages | : 400 |
| Release | : 2019-08-30 |
| Genre | : |
| ISBN | : 9780367390679 |
The costs associated with a drug's clinical trials are so significant that it has become necessary to validate both its safety and efficacy in animal models prior to the continued study of the drug in humans. Featuring contributions from distinguished researchers in the field of cognitive therapy research, Animal Models of Cognitive Impairment examines some of the most popular and successful animal archetypes used in the context of drug discovery. It provides integrated coverage of the latest research concerning neuronal systems relevant to cognitive function and dysfunction, assimilating reviews of this research within the context of each chapter. This approach is unique in that it brings together molecular and neurochemical methodologies, behavioral applications in translational models, and clinical applications. The book comprehensively discusses a wide variety of animal models of cognitive impairment, including genetic, lesion, pharmacological, and aging related impairments. It also explores the significance of this research in regards to the treatment of various addictions and disorders such as stroke, autism, Alzheimer's, schizophrenia, and ADHD. Edited by two renowned authorities in the field, Animal Models of Cognitive Impairment is a timely book that provides integrated coverage of cutting-edge research that concerns neuronal systems relevant to cognitive function and dysfunction.
| Author | : Leslie L. Iversen |
| Publisher | : |
| Total Pages | : 608 |
| Release | : 1983 |
| Genre | : Neuropharmacology |
| ISBN | : |
| Author | : Jerry J. Buccafusco |
| Publisher | : CRC Press |
| Total Pages | : 341 |
| Release | : 2000-08-29 |
| Genre | : Medical |
| ISBN | : 1420041819 |
Using the most well-studied behavioral analyses of animal subjects to promote a better understanding of the effects of disease and the effects of new therapeutic treatments on human cognition, Methods of Behavior Analysis in Neuroscience provides a reference manual for molecular and cellular research scientists in both academia and the pharmaceutic
| Author | : Federico Bermudez-Rattoni |
| Publisher | : CRC Press |
| Total Pages | : 368 |
| Release | : 2007-04-17 |
| Genre | : Psychology |
| ISBN | : 1420008412 |
A comprehensive, multidisciplinary review, Neural Plasticity and Memory: From Genes to Brain Imaging provides an in-depth, up-to-date analysis of the study of the neurobiology of memory. Leading specialists share their scientific experience in the field, covering a wide range of topics where molecular, genetic, behavioral, and brain imaging techniq
| Author | : Jeffrey Kreutzer |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 0 |
| Release | : 2010-09-29 |
| Genre | : Education |
| ISBN | : 0387799478 |
Clinical neuropsychology is a rapidly evolving specialty whose practitioners serve patients with traumatic brain injury, stroke and other vascular impairments, brain tumors, epilepsy and nonepileptic seizure disorders, developmental disabilities, progressive neurological disorders, HIV- and AIDS-related disorders, and dementia. . Services include evaluation, treatment, and case consultation in child, adult, and the expanding geriatric population in medical and community settings. The clinical goal always is to restore and maximize cognitive and psychological functioning in an injured or compromised brain. Most neuropsychology reference books focus primarily on assessment and diagnosis, and to date none has been encyclopedic in format. Clinicians, patients, and family members recognize that evaluation and diagnosis is only a starting point for the treatment and recovery process. During the past decade there has been a proliferation of programs, both hospital- and clinic-based, that provide rehabilitation, treatment, and treatment planning services. This encyclopedia will serve as a unified, comprehensive reference for professionals involved in the diagnosis, evaluation, and rehabilitation of adult patients and children with neuropsychological disorders.
| Author | : Institute of Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 172 |
| Release | : 2002-01-07 |
| Genre | : Medical |
| ISBN | : 0309082587 |
This report from the Committee on Military Nutrition Research reviews the history of caffeine usage, the metabolism of caffeine, and its physiological effects. The effects of caffeine on physical performance, cognitive function and alertness, and alleviation of sleep deprivation impairments are discussed in light of recent scientific literature. The impact of caffeine consumption on various aspects of health, including cardiovascular disease, reproduction, bone mineral density, and fluid homeostasis are reviewed. The behavioral effects of caffeine are also discussed, including the effect of caffeine on reaction to stress, withdrawal effects, and detrimental effects of high intakes. The amounts of caffeine found to enhance vigilance and reaction time consistently are reviewed and recommendations are made with respect to amounts of caffeine appropriate for maintaining alertness of military personnel during field operations. Recommendations are also provided on the need for appropriate labeling of caffeine-containing supplements, and education of military personnel on the use of these supplements. A brief review of some alternatives to caffeine is also provided.
| Author | : M.A. Steiner |
| Publisher | : Karger Medical and Scientific Publishers |
| Total Pages | : 165 |
| Release | : 2021-05-28 |
| Genre | : Health & Fitness |
| ISBN | : 3318068446 |
The orexin system, discovered in 1998, has emerged as a crucial player in regulating the sleep and wake balance inside our brain. This discovery has sparked a burst of novel and dynamic research on the physiology and pathology of sleep. The Orexin System: Basic Science and Role in Sleep Pathology honors this research and the authors share their ideas and perspectives on the novel developments within the field. The book examines the intricate role of the orexin system in regulating sleep and wake, and its interaction with other wake-regulating systems. The orexin system is dissected at the cellular and molecular level to explore the diversity of the orexin-producing neurons, their projections, and their signaling pathways. Additionally, the book discusses the diseases which are associated with a dysfunctional orexin system, such as narcolepsy, insomnia, substance abuse, and Alzheimer’s disease, and explores the new potential therapeutic applications derived from the burst of research around this fascinating system. This publication is essential reading for neurobiologists, neurologists, psychopharmacologists, sleep researchers, and other researchers and clinical scientists interested in sleep, sleep research, insomnia, and medicine in general.
| Author | : Gabriel G. Nahas |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 792 |
| Release | : 1999-04-05 |
| Genre | : Medical |
| ISBN | : 1592597106 |
Leading physicians and scientists from around the world critically examine the pharmacological and molecular basis of the therapeutic properties of marihuana and its active ingredient, THC. They detail the broad array of marihuana's effects on brain function, the immune system, male and female reproductive functions, and cardiac and pulmonary functions, as well as evaluate its clinical applications in psychiatry, glaucoma, pain management, cancer chemotherapy, and AIDS treatment. Their studies indicate that marihuana persistently impairs the brain and reproductive function, and that marihuana smoke is more toxic and damaging to the lung than tobacco smoke. Marihuana and Medicine's reports of the latest findings on the pharmacological and molecular mechanisms of marihuana and of its clinical manifestations will be essential reading for physicians, psychiatrists, pharmacologists, health-care professionals, policy makers, public health officials, and attorneys.
| Author | : |
| Publisher | : Academic Press |
| Total Pages | : 602 |
| Release | : 2018-11-16 |
| Genre | : Medical |
| ISBN | : 0128120142 |
Handbook of Object Novelty Recognition, Volume 26, synthesizes the empirical and theoretical advances in the field of object recognition and memory that have occurred since the development of the spontaneous object recognition task. The book is divided into four sections, covering vision and perception of object features and attributions, definitions of concepts that are associated with object recognition, the influence of brain lesions and drugs on various memory functions and processes, and models of neuropsychiatric disorders based on spontaneous object recognition tasks. A final section covers genetic and developmental studies and gender and hormone studies. - Details the brain structures and the neural circuits that underlie memory of objects, including vision and olfaction - Provides a thorough description of the object novelty recognition task, variations on the basic task, and methods and techniques to help researchers avoid common pitfalls - Assists researchers in understanding all aspects of object memory, conducting object novelty recognition tests, and producing reliable, reproducible results
