Alkaloids

Alkaloids
Author: Tadeusz Aniszewski
Publisher: Elsevier
Total Pages: 494
Release: 2015-04-25
Genre: Science
ISBN: 0444594620

Alkaloids - Secrets of Life: Alkaloid Chemistry, Biological Significance, Applications and Ecological Role, Second Edition provides knowledge on structural typology, biosynthesis and metabolism in relation to recent research work on alkaloids, considering an organic chemistry approach to alkaloids using biological and ecological explanation. The book approaches several questions and unresearched areas that persist in this field of research. It provides a beneficial text for academics, professionals or anyone who is interested in the fascinating subject of alkaloids. Each chapter features an abstract. Appendices, a listing of alkaloids, and plants containing alkaloids are all included, as are basic protocols of alkaloid analysis. - Presents the ecological role of alkaloids in nature and ecosystems interdisciplinary - Examines alkaloids from chemistry, biology and ecology viewpoints - A single handy reference volume comprehensively reviews the origin of alkaloids and their biological uses - Over 80% new information, including new chapters on the ecological role of alkaloids in nature and ecosystems and extraction of alkaloids

Biocatalysis

Biocatalysis
Author: Qayyum Husain
Publisher: Springer Nature
Total Pages: 341
Release: 2019-09-03
Genre: Science
ISBN: 3030250237

This book introduces readers to industrially important enzymes and discusses in detail their structures and functions, as well as their manifold applications. Due to their selective biocatalytic capabilities, enzymes are used in a broad range of industries and processes. The book highlights selected enzymes and their applications in agriculture, food processing and discoloration, as well as their role in biomedicine. In turn, it discusses biochemical engineering strategies such as enzyme immobilization, metabolic engineering, and cross-linkage of enzyme aggregates, and critically weighs their pros and cons. Offering a wealth of information, and stimulating further research by presenting new concepts on enzymatic catalytic functions in basic and applied contexts, the book represents a valuable asset for researchers from academia and industry who are engaged in biochemical engineering, microbiology and biotechnology.

Directory of Graduate Research

Directory of Graduate Research
Author: American Chemical Society. Committee on Professional Training
Publisher:
Total Pages: 1932
Release: 2005
Genre: Biochemistry
ISBN:

Faculties, publications and doctoral theses in departments or divisions of chemistry, chemical engineering, biochemistry and pharmaceutical and/or medicinal chemistry at universities in the United States and Canada.

Therapeutic Use of Medicinal Plants and their Extracts: Volume 2

Therapeutic Use of Medicinal Plants and their Extracts: Volume 2
Author: A.N.M. Alamgir
Publisher: Springer
Total Pages: 0
Release: 2019-02-14
Genre: Medical
ISBN: 9783030064235

This book starts with a general introduction to phytochemistry, followed by chapters on plant constituents, their origins and chemistry, but also discussing animal-, microorganism- and mineral-based drugs. Further chapters cover vitamins, food additives and excipients as well as xenobiotics and poisons. The book also explores the herbal approach to disease management and molecular pharmacognosy and introduces methods of qualitative and quantitative analysis of plant constituents. Phytochemicals are classified as primary (e.g. carbohydrates, lipids, amino acid derivations, etc.) or secondary (e.g. alkaloids, terpenes and terpenoids, phenolic compounds, glycosides, etc.) metabolites according to their metabolic route of origin, chemical structure and function. A wide variety of primary and secondary phytochemicals are present in medicinal plants, some of which are active phytomedicines and some of which are pharmaceutical excipients.

Anticancer Agents from Natural Products

Anticancer Agents from Natural Products
Author: Gordon M. Cragg
Publisher: CRC Press
Total Pages: 610
Release: 2005-06-13
Genre: Medical
ISBN: 1420039652

Plants, marine organisms, and microorganisms have evolved complex chemical defense and signaling systems that are designed to protect them from predators and provide other biological benefits. These organisms thus produce substances containing novel chemotypes that may have beneficial effects for humans. As collection methods improve and new screen

Natural Products

Natural Products
Author: Lixin Zhang
Publisher: Springer Science & Business Media
Total Pages: 380
Release: 2007-11-17
Genre: Medical
ISBN: 1592599761

A fresh examination of the past successes of natural products as medicines and their new future from both conventional and new technologies. High-performance liquid chromatography profiling, combinatorial synthesis, genomics, proteomics, DNA shuffling, bioinformatics, and genetic manipulation all now make it possible to rapidly evaluate the activities of extracts as well as purified components derived from microbes, plants, and marine organisms. The authors apply these methods to new natural product drug discoveries, to microbial diversity, to specific groups of products (Chinese herbal drugs, antitumor drugs from microbes and plants, terpenoids, and arsenic compounds), and to specific sources (the sea, rainforest, and endophytes). These new opportunities show how research and development trends in the pharmaceutical industry can advance to include both synthetic compounds and natural products, and how this paradigm shift can be more productive and efficacious.

Cancer Therapeutics

Cancer Therapeutics
Author: Beverly A. Teicher
Publisher: Springer Science & Business Media
Total Pages: 338
Release: 1997
Genre: Medical
ISBN:

This comprehensive review of existing and potential anticancer drugs and therapies by leading researchers from academia, government laboratories, and pharmaceutical companies offers essential insight into what has been accomplished and where the experimental therapy of cancer is going. The authoritative contributors illuminate the current status of the major molecules of cancer treatment, ranging from the nitrogen mustards through platinum complexes to interferons, cytokines, growth factors and their inhibitors, and on to immunotoxins, antisense oligonucleotides, and gene therapy. A companion volume by the same editor (Anticancer Drug Development Guide: Preclinical and Clinical Screening and Approval) details the processes by which new anticancer drugs are approved. These two volumes in the Cancer Drug Discovery and Development series reveal how and why molecules become anticancer drugs and thus offer a blueprint for the present and the future of the field.

Redox Biocatalysis

Redox Biocatalysis
Author: Daniela Gamenara
Publisher: John Wiley & Sons
Total Pages: 681
Release: 2012-09-18
Genre: Science
ISBN: 1118409329

Paves the way for new industrial applications using redox biocatalysis Increasingly, researchers rely on the use of enzymes to perform redox processes as they search for novel industrial synthetic routes. In order to support and advance their investigations, this book provides a comprehensive and current overview of the use of redox enzymes and enzyme-mediated oxidative processes, with an emphasis on the role of redox enzymes in chemical transformations. The authors examine the full range of topics in the field, from basic principles to new and emerging research and applications. Moreover, they explore everything from laboratory-scale procedures to industrial manufacturing. Redox Biocatalysis begins with a discussion of the biochemical features of redox enzymes as well as cofactors and cofactor regeneration methods. Next, the authors present a variety of topics and materials to the research and development of full-scale industrial applications, including: Biocatalytic applications of redox enzymes such as dehydrogenases, oxygenases, oxidases, and peroxidases Enzyme-mediated oxidative processes based on biocatalytic promiscuity All the steps from enzyme discovery to robust industrial processes, including directed evolution, high-throughput screening, and medium engineering Case studies tracing the development of industrial applications using biocatalytic redox reactions Each chapter ends with concluding remarks, underscoring the key scientific principles and processes. Extensive references serve as a gateway to the growing body of research in the field. Researchers in both academia and industry will find this book an indispensable reference for redox biotransformations, guiding them from underlying core principles to new discoveries and emerging industrial applications.