Applied Rna Bioscience
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Author | : Seiji Masuda |
Publisher | : Springer |
Total Pages | : 286 |
Release | : 2018-04-10 |
Genre | : Science |
ISBN | : 981108372X |
The focus of this book is to introduce up-to-date information on applications and practical use of RNA for agriculture, biotechnology and medicine. It provides unique ideas, tools, and methods in detail from a variety of scientific and technical disciplines. RNA science has progressed enormously in recent decades, and vast amounts of information on RNA functions and their regulatory mechanisms are becoming available. Such a progress opened the door to an age of practical application of RNA in many fields including agriculture, plant science, medical science, brewing and fermentation technology, and material production. This book inspires its readership and contributes to not only expansion in application of RNA but also to basic research.
Author | : |
Publisher | : |
Total Pages | : 0 |
Release | : 2002 |
Genre | : Cells |
ISBN | : 9780815332183 |
Author | : Torben Heick Jensen |
Publisher | : Springer Science & Business Media |
Total Pages | : 161 |
Release | : 2011-06-29 |
Genre | : Medical |
ISBN | : 1441978410 |
The diversity of RNAs inside living cells is amazing. We have known of the more “classic” RNA species: mRNA, tRNA, rRNA, snRNA and snoRNA for some time now, but in a steady stream new types of molecules are being described as it is becoming clear that most of the genomic information of cells ends up in RNA. To deal with the enormous load of resulting RNA processing and degradation reactions, cells need adequate and efficient molecular machines. The RNA exosome is arising as a major facilitator to this effect. Structural and functional data gathered over the last decade have illustrated the biochemical importance of this multimeric complex and its many co-factors, revealing its enormous regulatory power. By gathering some of the most prominent researchers in the exosome field, it is the aim of this volume to introduce this fascinating protein complex as well as to give a timely and rich account of its many functions. The exosome was discovered more than a decade ago by Phil Mitchell and David Tollervey by its ability to trim the 3’end of yeast, S. cerevisiae, 5. 8S rRNA. In a historic account they laid out the events surrounding this identification and the subsequent birth of the research field. In the chapter by Kurt Januszyk and Christopher Lima the structural organization of eukaryotic exosomes and their evolutionary counterparts in bacteria and archaea are discussed in large part through presentation of structures.
Author | : Institute of Medicine |
Publisher | : National Academies Press |
Total Pages | : 354 |
Release | : 2012-09-13 |
Genre | : Science |
ISBN | : 0309224187 |
Technologies collectively called omics enable simultaneous measurement of an enormous number of biomolecules; for example, genomics investigates thousands of DNA sequences, and proteomics examines large numbers of proteins. Scientists are using these technologies to develop innovative tests to detect disease and to predict a patient's likelihood of responding to specific drugs. Following a recent case involving premature use of omics-based tests in cancer clinical trials at Duke University, the NCI requested that the IOM establish a committee to recommend ways to strengthen omics-based test development and evaluation. This report identifies best practices to enhance development, evaluation, and translation of omics-based tests while simultaneously reinforcing steps to ensure that these tests are appropriately assessed for scientific validity before they are used to guide patient treatment in clinical trials.
Author | : Naoyuki Kataoka |
Publisher | : Frontiers Media SA |
Total Pages | : 123 |
Release | : 2019-10-15 |
Genre | : |
ISBN | : 2889630978 |
This Research Topic addresses the human diseases caused by a malfunction of the RNA metabolism. We aim at strengthening the link between fundamental research and therapeutic applications. In eukaryotes, RNA is transcribed from genomic DNA. RNA molecules undergo multiple post-transcriptional processes such as splicing, editing, modification, translation, and degradation. A defect, mis-regulation, or malfunction of these processes often results in diseases in humans, referred to as 'RNA diseases'. There is an increasing number of studies focused on RNA diseases, which are aimed at uncovering the fundamental molecular mechanisms at play in order to develop therapeutic approaches.
Author | : Seiji Masuda |
Publisher | : |
Total Pages | : |
Release | : 2018 |
Genre | : RNA |
ISBN | : 9789811083730 |
The focus of this book is to introduce up-to-date information on applications and practical use of RNA for agriculture, biotechnology and medicine. It provides unique ideas, tools, and methods in detail from a variety of scientific and technical disciplines. RNA science has progressed enormously in recent decades, and vast amounts of information on RNA functions and their regulatory mechanisms are becoming available. Such a progress opened the door to an age of practical application of RNA in many fields including agriculture, plant science, medical science, brewing and fermentation technology, and material production. This book inspires its readership and contributes to not only expansion in application of RNA but also to basic research.
Author | : Babak Arjmand |
Publisher | : Springer Nature |
Total Pages | : 208 |
Release | : 2019-11-14 |
Genre | : Science |
ISBN | : 3030277275 |
This book provides thorough coverage of high-throughput OMICs technologies for the monitoring of stem cells and regenerative medicine. Specific topics covered include the genomics, proteomics, and metabolomics aspects of regenerative medicine, metabolic profiling of mesenchymal stem cells, genome profiling of mesenchymal stem cells, OMICs monitoring of stem cell-derived exosomes, stem cell proteomics, lipidomics, OMICs profiling of cancer (stem) cells, and finally ethical considerations of OMICs-based investigations. Chapters are authored by world-renowned scientists who have valuable expertise in the field of OMICs and regenerative medicine. Genomics, Proteomics, and Metabolomics: Stem Cells Monitoring in Regenerative Medicine, part of Springer’s Stem Cell Biology and Regenerative Medicine series, is essential reading for researchers, clinicians, biologists, biochemists, and pharmaceutical experts conducting research in the fields of stem cell biology, molecular aspects of stem cell research, tissue engineering, regenerative medicine, cellular therapy, OMICs, bioinformatics, and ethics.
Author | : |
Publisher | : ScholarlyEditions |
Total Pages | : 958 |
Release | : 2012-12-26 |
Genre | : Medical |
ISBN | : 1464991219 |
Primate Lentiviruses—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Primate Lentiviruses. The editors have built Primate Lentiviruses—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Primate Lentiviruses in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Primate Lentiviruses—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Author | : |
Publisher | : ScholarlyEditions |
Total Pages | : 484 |
Release | : 2012-12-26 |
Genre | : Medical |
ISBN | : 1464993084 |
Advances in Enterobacteriaceae Research and Treatment / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Enterobacteriaceae. The editors have built Advances in Enterobacteriaceae Research and Treatment / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Enterobacteriaceae in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Enterobacteriaceae Research and Treatment / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Author | : K. Sahayaraj |
Publisher | : Springer |
Total Pages | : 387 |
Release | : 2014-07-10 |
Genre | : Technology & Engineering |
ISBN | : 8132218779 |
Currently, the major challenge of humanity is focused on population growth through agricultural production in order to meet the demand for food. The food crunch is mainly due to pest and disease. Traditional methods, synthetic insecticides and microbicides cause health hazards to human beings, domestic animals and also affect our immediate environments. Serious concerns were implemented by both developing and developed countries as Integrated Pest Management (IPM) and Bio-intensive Integrated Pest Management (BIPM) systems where biopesticides play an important role worldwide. The available books are limited to particular aspects of biopesticides. Hence, it is imperative to bring out a holistic documentation which will provide the reader information on all aspects of biopesticides. The book consists of five sections namely microbials, botanicals, natural enemies semio- chemicals and biotechnology and equipments, bioinformatics tools and IPM. In Section I, microbial deals with utilization of Bacillus in control of phytonematodes; biological control of pest and diseases with fluorescent pseudomonads, entomopathogenic fungus and entomopathogenic nematodes in pest management, microbial viral insecticides and microbial elicitors to induce immunity for plant disease control in chilli and tomato. Importance of plant essential oils, botanicals in endocrine disruption, relevance of botanicals and use of plant volatile on pest management has been discussed in Section II. Importance and role of reduviidae, weaver ants, ground beetles, Odonatas, spiders in biological control has been discussed in Section III. In addition, genetic improvement of biocontrol agents for sustainable pest management has also been highlighted. In Section IV, classical practices and pheromone, kairomonal enhancement to natural enemies and use of transgenic plants in insect control are highlighted. Equipment and their application methodologies for application of biopesticides; relevance of bioinformatics in biopesticides management; pest management of soybean, bio fouling and eco friendly antifoulants have been highlighted in Section V. Each chapter has objectives and conclusion along with recommendations.