Antioxidants In Biology And Medicine
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| Author | : Edwin Nessim Frankel |
| Publisher | : |
| Total Pages | : 254 |
| Release | : 2007 |
| Genre | : Antioxidants |
| ISBN | : 9780857097903 |
Designed to help all those who need to prevent or control oxidation, especially in food products, or to understand the properties of antioxidants in food, nutrition, health and medicine, this title covers chapters such as the chemistry of antioxidation, antioxidant action in multi-phase systems, antioxidants in biology, and among other topics. The field of antioxidants has expanded over the last six decades into a wide variety of multi-disciplinary areas that impact foods and health. Antioxidants in food and biology: Facts and fiction is a handbook designed to help all those who need to prevent or control oxidation, especially in food products, or to understand the properties of antioxidants in food, nutrition, health and medicine. It conveys the complexity of antioxidant chemistry by providing an appreciation of the various phenomena that affect oxidation and its inhibition in foods and biological systems. Beginning with the underlying chemistry, the book moves on to explain how the activity of antioxidants is affected at the interface of complex multiphase lipid systems and to discuss the problems of evaluating the activities of antioxidants in foods and biological systems. After reviewing the antioxidants present in various foods, the author addresses the hypothesis that the health of an individual is influenced by the efficiency of various protection systems against oxidant damage. He also considers whether or not additional or more effective natural antioxidants are needed in our diet to reduce oxidative stress from dietary and environmental factors, and to thus reduce the risk of cardiovascular disease.
| Author | : Barry Halliwell |
| Publisher | : OUP Oxford |
| Total Pages | : 961 |
| Release | : 2015-08-21 |
| Genre | : Science |
| ISBN | : 0191026980 |
Free Radicals in Biology and Medicine has become a classic text in the field of free radical and antioxidant research. Now in its fifth edition, the book has been comprehensively rewritten and updated whilst maintaining the clarity of its predecessors. Two new chapters discuss 'in vivo' and 'dietary' antioxidants, the first emphasising the role of peroxiredoxins and integrated defence mechanisms which allow useful roles for ROS, and the second containing new information on the role of fruits, vegetables, and vitamins in health and disease. This new edition also contains expanded coverage of the mechanisms of oxidative damage to lipids, DNA, and proteins (and the repair of such damage), and the roles played by reactive species in signal transduction, cell survival, death, human reproduction, defence mechanisms of animals and plants against pathogens, and other important biological events. The methodologies available to measure reactive species and oxidative damage (and their potential pitfalls) have been fully updated, as have the topics of phagocyte ROS production, NADPH oxidase enzymes, and toxicology. There is a detailed and critical evaluation of the role of free radicals and other reactive species in human diseases, especially cancer, cardiovascular, chronic inflammatory and neurodegenerative diseases. New aspects of ageing are discussed in the context of the free radical theory of ageing. This book is recommended as a comprehensive introduction to the field for students, educators, clinicians, and researchers. It will also be an invaluable companion to all those interested in the role of free radicals in the life and biomedical sciences.
| Author | : Yunbo Li |
| Publisher | : |
| Total Pages | : 422 |
| Release | : 2011 |
| Genre | : Active oxygen |
| ISBN | : 9781612094663 |
| Author | : Michael Simic |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 1064 |
| Release | : 2013-03-09 |
| Genre | : Science |
| ISBN | : 1468455680 |
This book is based on the papers presented at the "Fourth International Congress on Oxygen Radicals (4-ICOR)," held June 27 - July 3, 1987, at the University of California, La Jolla. The chapters deal with the phenomena associated with highly reactive oxygen species (hydroxy, peroxy, alkoxy, aroxy, and superoxide radicals, as well as singlet oxygen) and their peroxidation products (hydrogen peroxide, hydroperoxides, peroxides, and epoxides) as they relate to the fields of chemistry, food technology, nutrition, biology, pharmacology, and medicine. The kinetics, energetics, and mechanistic aspects of the reactions of these species and the interrelationship of oxygen radicals (or any other free radicals) and peroxidized products have been emphasized. Special attention is focused on the mechanisms of the generation of free radicals and peroxy products in biosystems and on the adverse effects of these radicals and products in humans. The topics span the continuum from the simple chemistry of model systems to the complex considerations of clinical medicine. The book also explores the mechanisms of agents that protect against free radicals and peroxy products in vitro and in vivo. These agents include antioxidants used in materials, food antioxidants, physiological antioxidants, and antioxienzymes (SOD, glutathione peroxidase, and catalases). The use of these inhibitors to prevent damage to organs being prepared for transplantation, thereby maintaining the quality of transplanted organs and/or extending their "shelf-life," also is examined.
| Author | : Ismail Laher |
| Publisher | : Springer |
| Total Pages | : 0 |
| Release | : 2014-06-16 |
| Genre | : Medical |
| ISBN | : 9783642300172 |
The focus of this collection of illustrated reviews is to discuss the systems biology of free radicals and anti-oxidants. Free radical induced cellular damage in a variety of tissues and organs is reviewed, with detailed discussion of molecular and cellular mechanisms. The collection is aimed at those new to the field, as well as clinicians and scientists with long standing interests in free radical biology. A feature of this collection is that the material also brings insights into various diseases where free radicals are thought to play a role. There is extensive discussion of the success and limitations of the use of antioxidants in several clinical settings.
| Author | : Rizwan Ahmad |
| Publisher | : BoD – Books on Demand |
| Total Pages | : 150 |
| Release | : 2018-08-01 |
| Genre | : Science |
| ISBN | : 1789235642 |
The current book entitled Free Radicals, Antioxidants, and Diseases gives an idea of detecting free radicals in vivo by newer techniques and provides insights into the roles played by various antioxidants in combating diseases caused by oxidative stress. The chapters included in this volume showcase new investigation in this field by the research groups around the world.
| Author | : Evgeny T. Denisov |
| Publisher | : CRC Press |
| Total Pages | : 1020 |
| Release | : 2005-03-29 |
| Genre | : Medical |
| ISBN | : 142003085X |
Providing a comprehensive review of reactions of oxidation for different classes of organic compounds and polymers, and biological processes mediated by free radicals, Oxidation and Antioxidants in Organic Chemistry and Biology puts the data and bibliographical information you need into one easy-to-use resource. You will find up-to-date information
| Author | : Robert Z. Hopkins |
| Publisher | : |
| Total Pages | : 252 |
| Release | : 2020-01-18 |
| Genre | : Medical |
| ISBN | : 9781680560107 |
A must-read book, written by world-renowned experts, on biological antioxidants and their health impact; Contents based exclusively on cutting-edge scientific discoveries published in highly influential peer-reviewed journals; Written in an accessible style and consistent format with full-color illustrations and self-assessment questions.
| Author | : |
| Publisher | : BoD – Books on Demand |
| Total Pages | : 132 |
| Release | : 2020-07-15 |
| Genre | : Science |
| ISBN | : 1789851432 |
Although free radicals perform some useful immune functions, they can also damage healthy cells through a process called oxidation. Antioxidants reduce the effect of free radicals by binding together with these harmful molecules, decreasing their destructive power. This book highlights various issues of free radical biology from the perspective of antioxidant defense mechanisms. It also provides useful information on gene modulation, radiation-generated reactive oxygen species-induced apoptosis in cancer, and environmental aspects associated with free radicals’ exposure on living systems.
| Author | : Donald Armstrong |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 351 |
| Release | : 2008-02-02 |
| Genre | : Science |
| ISBN | : 1592592740 |
In our first protocols book, Free Radical and Antioxidant Protocols (1), r- erence to in vivo, ex vivo, or in situ techniques were few compared to classical biochemical assays and only 6 of the 40 chapters were concerned with these applications. In our second book, Oxidative Stress Biomarkers and Antioxidant Protocols (2), which is being published concurrently with this third volume, Oxidants and Antioxidants: Ultrastructure and Molecular Biology Protocols, the number of such chapters has increased. The literature dealing with histoche- cal/cytochemical and immunohistochemical techniques and staining to identify cellular/subcellular sites of oxidative stress has expanded rapidly, as has the molecular biology methodology used to analyze free radical and antioxidant (AOX) reactions, as well as the monitoring of living tissue. A two-way search was performed for each technique listed in Table 1, coupled with “oxidative stress” using the PUBMED search engine from the National Library of Medicine at NIH. Most of the techniques involved in m- suring oxidative stress employ molecular biology or ultrastructural approaches. Of these techniques, histology, polymerase chain reaction, and Western blotting are the most widely used. Several forms of therapy are now available for patients with increased oxidative stress. In addition to standard antioxidant therapy supplementation in vivo and in vitro, photodynamic therapy (PDT) employs excitation of a photon-emitting compound delivered systemically for free radical-mediated necrosis of affected tissues, and stem cells are also being used to induce signaling events or replace antioxidant enzymes.
