Renin Angiotensin System and the Heart

Renin Angiotensin System and the Heart
Author: Walmor C. De Mello
Publisher: Wiley-Blackwell
Total Pages: 268
Release: 2004-04-30
Genre: Family & Relationships
ISBN:

Recent studies have shown that the heart possesses an intrinsic renin angiotensin system that is controlled by tissue-specific parameters that are activated by biomechanical stress. This book reviews the latest information on the way in which both the plasma and cardiac renin angiotensin systems affect heart function. It covers the cell and molecular biology of these systems, with contributions on renin synthesis, uptake and the intracellular signalling pathways. Particular insight comes from transgenic mouse models in which either mouse or human genes for various components of the renin angiotensin system are expressed. Other topics covered include wound healing as well as the trophic effects of aldosterone. Contains the most recent findings on the renin angiotensin system and the heart Written by an international team of distinguished scientists Covers both the cellular and molecular basis of the renin angiotensin system and the clinical relevance of this research

Aldosterone-Mineralocorticoid Receptor

Aldosterone-Mineralocorticoid Receptor
Author: Brian Harvey
Publisher: BoD – Books on Demand
Total Pages: 302
Release: 2019-09-25
Genre: Medical
ISBN: 1839621982

This book is an open access dissemination of the EU COST Action ADMIRE in Aldosterone/Mineralocorticoid Receptor (MR) physiology and pathophysiology. Aldosterone is the major hormone regulating blood pressure. Alterations in blood levels of aldosterone and genetic mutations in the MR receptor are major causes of hypertension and comorbidities. Many of the drugs in clinical use, and in development for treating hypertension, target aldosterone and MR actions in the kidney and cardiovascular system. The ADMIRE book assembles review chapters from 16 European ADMIRE laboratories providing the latest insights into mechanisms of aldosterone synthesis/secretion, aldosterone/MR physiology and signaling, and the pathophysiological roles of aldosterone/MR activation.

Meyler's Side Effects of Drugs

Meyler's Side Effects of Drugs
Author: Jeffrey K. Aronson
Publisher: Elsevier
Total Pages: 7629
Release: 2015-10-15
Genre: Medical
ISBN: 0444537163

Meyler's Side Effects of Drugs: The International Encyclopedia of Adverse Drug Reactions and Interactions, Sixteenth Edition, Seven Volume Set builds on the success of the 15 previous editions, providing an extensively reorganized and expanded resource that now comprises more than 1,500 individual drug articles with the most complete coverage of adverse reactions and interactions found anywhere. Each article contains detailed and authoritative information about the adverse effects of each drug, with comprehensive references to the primary literature, making this a must–have reference work for any academic or medical library, pharmacologist, regulatory organization, hospital dispensary, or pharmaceutical company. The online version of the book provides an unparalleled depth of coverage and functionality by offering convenient desktop access and enhanced features such as increased searchability, extensive internal cross-linking, and fully downloadable and printable full-text, HTML or PDF articles. Enhanced encyclopedic format with drug monographs now organized alphabetically Completely expanded coverage of each drug, with more than 1,500 drug articles and information on adverse reactions and interactions Clearer, systematic organization of information for easier reading, including case histories to provide perspective on each listing Extensive bibliography with over 40,000 references A must–have reference work for any academic or medical library, pharmacologist, regulatory organization, hospital dispensary, or pharmaceutical company

Hypertension in Postmenopausal Women

Hypertension in Postmenopausal Women
Author: Michel E. Safar
Publisher: Springer Science & Business Media
Total Pages: 125
Release: 2012-12-06
Genre: Medical
ISBN: 3642790771

On the occasion of the symposium on Hypertension in Postmenopausal Women (Monte Carlo, January 19-22, 1994), international scientists and clinicians discussed the various aspects of high blood pressure in older women. This volume presents an overview of this important aspect of both cardiology and gynecology. Special emphasis is given to the different approaches to antihypertension treatment.

Cardiac Remodeling and Failure

Cardiac Remodeling and Failure
Author: Pawan K. Singal
Publisher: Springer Science & Business Media
Total Pages: 570
Release: 2003-02-28
Genre: Medical
ISBN: 9781402071775

The importance of the developmental approach for experimental and clinical cardiology is indisputable. Clinical-epidemiological studies have clearly shown that the risk factors of serious cardiovascular diseases, such as atherosclerosis and ischemic heart disease, are already present during the early phases of ontogenetic development. Furthermore, congenital cardiovascular malformations remain the single largest cause of infant mortality from congenital defects in industrial countries. It is therefore not surprising that the interest of theoretical and clinical cardiologists in the developmental approach keeps increasing. Advances in molecular biology accelerated this trend substantially. This book is based on contributions presented at the international symposium The Developing Heart in Prague in May 2000. It is our contention that the biological, electrophysiological, morphological, functional, biochemical and functional approaches employed by distinguished scientists worldwide will provide the reader with a global picture for changes characterizing the developing heart. It should stimulate the curiosity of cardiovascular scientists in gaining insight into the mechanisms of normal and pathological development.

The Local Cardiac Renin-Angiotensin Aldosterone System

The Local Cardiac Renin-Angiotensin Aldosterone System
Author: Edward D. Frohlich
Publisher: Springer Science & Business Media
Total Pages: 187
Release: 2009-09-18
Genre: Medical
ISBN: 1441905286

Until recently, the renin-angiotensin-aldosterone system has been considered a systemic endocrine hormonal system exclusively. It is now known that each component of the renin-angiotensin system is produced, synthesized and indeed, present in many organisms including the heart and vessels. This volume presents the most recent clinical and laboratory experiences of the leading physicians and investigators in the field of the local cardiac renin-angiotensin aldosterone system. Cardiovascular, renal and hypertension oriented physicians, investigators and scientists would find this book of interest. Edward D. Frohlich, M.D., M.A.C.P, F.A.C.C., is the Alton Ochsner Distinguished Scientist at the Ochsner Clinic Foundation in New Orleans, Louisiana. He is also Professor of Medicine and of Physiology at Louisiana State University School of Medicine, New Orleans, and Clinical Professor of Medicine and Adjunct Professor of Pharmacology at Tulane University School of Medicine, New Orleans. He is past Editor-in-Chief of the American Heart Association journal HYPERTENSION. Richard N. Re, M.D., is the Section Head, Hypertension at the Ochsner Clinic Foundation in New Orleans, Louisiana. He is also Ochsner's Scientific Director of Research.

Disease Control Priorities, Third Edition (Volume 5)

Disease Control Priorities, Third Edition (Volume 5)
Author: Dorairaj Prabhakaran
Publisher: World Bank Publications
Total Pages: 948
Release: 2017-11-17
Genre: Medical
ISBN: 1464805202

Cardiovascular, respiratory, and related conditions cause more than 40 percent of all deaths globally, and their substantial burden is rising, particularly in low- and middle-income countries (LMICs). Their burden extends well beyond health effects to include significant economic and societal consequences. Most of these conditions are related, share risk factors, and have common control measures at the clinical, population, and policy levels. Lives can be extended and improved when these diseases are prevented, detected, and managed. This volume summarizes current knowledge and presents evidence-based interventions that are effective, cost-effective, and scalable in LMICs.

Rutherford's Vascular Surgery and Endovascular Therapy, E-Book

Rutherford's Vascular Surgery and Endovascular Therapy, E-Book
Author: Anton N Sidawy
Publisher: Elsevier Health Sciences
Total Pages: 2838
Release: 2018-04-03
Genre: Medical
ISBN: 0323581307

Through nine outstanding editions, Rutherford's Vascular Surgery and Endovascular Therapy has been the gold standard text in this fast-changing, complex field. Published in association with the Society for Vascular Surgery, this state-of-the-art reference by Drs. Anton N. Sidawy and Bruce A. Perler is a must-have for vascular surgeons, interventionalists, vascular medicine specialists, and trainees, as well as general surgeons, interventional radiologists, and cardiologists that depend upon "Rutherford’s" in their practice. It offers authoritative guidance from the most respected and innovative global thought leaders and clinical and basic science experts in the diagnosis and treatment of circulatory disease. Incorporates medical, endovascular, and surgical treatment, as well as diagnostic techniques, decision making, and fundamental vascular biology. Features all vascular imaging techniques, offering a non-invasive evaluation of both the morphology and hemodynamics of the vascular system. Provides unparalleled insight from multidisciplinary leaders worldwide, who share their expertise on the most appropriate contemporary and future treatment of circulatory disease. Employs a full-color layout and images so you can view clinical and physical findings and operative techniques more vividly. Includes 40 new chapters incorporating a shorter, more focused format with a summary for each chapter that provides a quick access to key information – ideal for consultation situations as well as daily practice. Some of these chapters are organized in new sections dedicated to open operative exposure and vessel dissection techniques, diabetic foot, Pediatric Vascular Disease, and practice management issues; areas in the specialty that clinicians frequently face but seldom detailed in other vascular texts nor in earlier Rutherford editions. Covers hot topics such as endovascular therapy of aortic arch and thoracoabdominal aortic aneurysm disease, including the evolving management of aortic dissections. Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

The Renin-Angiotensin-Aldosterone System

The Renin-Angiotensin-Aldosterone System
Author: Sean E. Thatcher
Publisher: Humana Press
Total Pages: 201
Release: 2017-05-13
Genre: Science
ISBN: 9781493970285

This volume discusses protocols that aid in measuring different components in the renin-angiotensin-aldosterone system (RAAS). The book also looks at the methods used to assess angiotensin peptides and discerning the influence of RAAS components on different mammalian diseases. The chapters cover topics such as the use of fluorescent substrate to measure ACE2 activity in the mouse abdominal aorta, blood pressure monitoring using the radio telemetry method, and the analysis of angiotensin metabolism in the kidney using mass spectrometry. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting edge and comprehensive, The Renin-Angiotensin-Aldosterone Systems: Methods and Protocols is a valuable resource that provides scientists and researchers with the best approaches to examine RAAS.

Goodman and Gilman's Pharmacological Basis of Therapeutics Digital Edition

Goodman and Gilman's Pharmacological Basis of Therapeutics Digital Edition
Author: Keith Parker
Publisher: McGraw-Hill Professional Publishing
Total Pages: 2021
Release: 2005-09
Genre: Medical
ISBN: 9780071468046

This package offers the combined benefits of both the print and the web-based presentation, for the very reasonable additional price of approximately $60 over the cost of the book alone. G&G is the acknowledged authority on the properties, mechanisms, and uses of the major drug classes. One of the most successful books in the history of medical publishing (more than 1,000,000 copies sold!), it is renowned worldwide for detailed but clinically applicable coverage. The G&G Digital Edition includes LOT access to G&G On Line, with its advanced search engine, PDA “cut and paste” capability, hyperlinked references, and other new features developed specifically for G&G On Line.