Anatomy and Histology of the Laboratory Rat in Toxicology and Biomedical Research

Anatomy and Histology of the Laboratory Rat in Toxicology and Biomedical Research
Author: Robert L. Maynard
Publisher: Academic Press
Total Pages: 379
Release: 2019-02-08
Genre: Medical
ISBN: 0128118717

Anatomy and Histology of the Laboratory Rat in Toxicology and Biomedical Research presents the detailed systematic anatomy of the rat, with a focus on toxicological needs. Most large works dealing with the laboratory rat provide a chapter on anatomy, but fall far short of the detailed account in this book which also focuses on the needs of toxicologists and others who use the rat as a laboratory animal. The book includes detailed guides on dissection methods and the location of specific tissues in specific organ systems. Crucially, the book includes classic illustrations from Miss H. G. Q. Rowett, along with new color photo-micrographs. Written by two of the top authors in their fields, this book can be used as a reference guide and teaching aid for students and researchers in toxicology. In addition, veterinary/medical students, researchers who utilize animals in biomedical research, and researchers in zoology, comparative anatomy, physiology and pharmacology will find this book to be a great resource. - Illustrated with over a hundred black and white and color images to assist understanding - Contains detailed descriptions and explanations to accompany all images helping with self-study - Designed for toxicologic research for people from diverse backgrounds including biochemistry, pharmacology, physiology, immunology, and general biomedical sciences

Comparative Anatomy and Histology

Comparative Anatomy and Histology
Author: Piper M. Treuting
Publisher: Academic Press
Total Pages: 573
Release: 2017-08-29
Genre: Science
ISBN: 0128029196

The second edition of Comparative Anatomy and Histology is aimed at the new rodent investigator as well as medical and veterinary pathologists who need to expand their knowledge base into comparative anatomy and histology. It guides the reader through normal mouse and rat anatomy and histology using direct comparison to the human. The side by side comparison of mouse, rat, and human tissues highlight the unique biology of the rodents, which has great impact on the validation of rodent models of human disease. - Offers the only comprehensive source for comparing mouse, rat, and human anatomy and histology through over 1500 full-color images, in one reference work - Enables human and veterinary pathologists to examine tissue samples with greater accuracy and confidence - Teaches biomedical researchers to examine the histologic changes in their model rodents - Experts from both human and veterinary fields take readers through each organ system in a side-by-side comparative approach to anatomy and histology - human Netter anatomy images along with Netter-style rodent images

The Laboratory Rat

The Laboratory Rat
Author: George J. Krinke
Publisher: Elsevier
Total Pages: 783
Release: 2000-06-20
Genre: Science
ISBN: 0080533469

This reference series will provide all researchers using laboratory animals with comprehensive practical information on the various species. Each title in the series is devoted to a particular species, and draws together all available data in a "one-stop", easily accessible source. Each has similar format, with sections on the strains available, their husbandry, and special diets. Also included are sections on gross anatomy, endocrinology, and reproduction, followed by more detailed sections on neuroanatomy, vasculature, cell biology, and histology of particular organs and structures, and a section on molecular biology. High quality illustrations are included throughout and a color plate section is provided. A glossary, list of equipment suppliers, and "Quick Reference Section" are added features. The "Quick Reference Section" brings together all tables from the text, allowing readers to find data swiftly. The first volume in The Handbook of Experimental Animals Series, The Laboratory Rat, provides researchers in academia and industry using laboratory animals with comprehensive, practical information on the species. The Laboratory Rat has been divided into eight sections dealing with:* Strains and their selection for research* Housing and maintenance* Pathogens and diseases* Breeding and reproduction* Anatomy* Physiology* Procedures, including experimental surgery* Emerging techniques, including genetic engineering and molecular technologyKey Features* Provides a valuable, comprehensive reference source for anybody working with the laboratory rat* Formatted in a two-color, user-friendly layout* Includes high-quality illustrations throughout as well as a color plate section* Glossary* Tables in the text are also arranged into one Quick Reference Section for ease of access to the data* Appendix of equipment suppliers

Functional Anatomy of the Vertebrates

Functional Anatomy of the Vertebrates
Author: Karel F. Liem
Publisher: Cengage Learning
Total Pages: 798
Release: 2001
Genre: Anatomy, Comparative
ISBN:

This book introduces students to the groups of vertebrates and explores the anatomical evolution of vertebrates within the context of the functional interrelationships of organs and the changing environments to which vertebrates have adapted. The text contains all of the material taught in classic comparative anatomy courses, but integrates this material with current research in functional anatomy. This integration adds a new dimension to our understanding of structure and helps students understand the evolution of vertebrates.

Hemopoietic System

Hemopoietic System
Author: Thomas C. Jones
Publisher: Springer Science & Business Media
Total Pages: 644
Release: 2012-12-06
Genre: Medical
ISBN: 3642841104

The International Life Sciences Institute (ILSI) was estab lished in 1978 to stimulate and support scientific research and educational programs related to nutrition, toxicology, and food safety, and to encourage cooperation in these programs among scientists in universities, industry, and government agencies to assist in the resolution of health and safety issues. To supplement and enhance these efforts, ILSI has made a major commitment to supporting programs to harmon ize toxicologic testing, to advance a more uniform inter pretation of bioassay results worldwide, to promote a common understanding of lesion classifications, and to encourage wide discussion of these topics among scien tists. The Monographs on the Pathology of Laboratory Ani mals are designed to facilitate communication among those involved in the safety testing of foods, drugs, and chemicals. The complete set will cover all organ systems and is intended for use by pathologists, toxicologists, and others concerned with evaluating toxicity and carcinogen icity studies. The international nature of the project - as reflected in the composition of the editorial board and the diversity of the authors and editors - strengthens our ex pectations that understanding and cooperation will be im proved worldwide through the series. Alex Malaspina President International Life Sciences Institute Preface This book, on the hemopoietic system, is the eighth volume of a set prepared under the sponsorship of the International Life Sciences In stitute (ILSI).

The Rat Nervous System

The Rat Nervous System
Author: George Paxinos
Publisher:
Total Pages: 1136
Release: 1995
Genre: Brain
ISBN: 9780125476355

This text provides a description of the cytoarchitecture, chemoarchitecture, and connectivity of the rat nervous system. In addition it offers updated and supplemented information on the peripheral motor, peripheral somatosensor, vascular, central motor, pain, and additional neurotransmitter systems.

Comparative Anatomy of the Mouse and the Rat

Comparative Anatomy of the Mouse and the Rat
Author: Gheorghe M. Constantinescu
Publisher: Editeurs divers Royaume-Uni & Irlande
Total Pages: 0
Release: 2018
Genre: Laboratory animals
ISBN: 9781138624030

This Atlas provides detailed comparative anatomical information for those who work with mice and rats in animal research or veterinary medicine. Information is provided about the anatomical features and landmarks for conducting a physical examination, collecting biological samples, injecting, using imaging modalities, and performing surgeries.

The Extraordinary Biology of the Naked Mole-Rat

The Extraordinary Biology of the Naked Mole-Rat
Author: Rochelle Buffenstein
Publisher: Springer Nature
Total Pages: 450
Release: 2021-08-23
Genre: Medical
ISBN: 3030659437

This volume focuses on the huge advances in the last 25 years on the use of this animal model for biomedical research (cancer, heart disease and neurodegeneration), fundamental neuroscience and basic subterranean biology. In 2013, Science magazine named the naked mole-rat as the Vertebrate of the Year. This was partly due to research carried out documenting its extreme longevity, negligible senescence, and prolonged maintenance of cancer free, good health well into old age as well as seminal work on mechanisms involved in these processes, pain and hypoxia resistance. In addition to this research focus on longevity and chronic diseases such as cancer and cardiovascular disease, the naked mole-rat has also made a substantial contribution to the fields of ecophysiology, neuroscience and behavior. With international contributions, this book provides a valuable text for zoological students, behavioral scientists and biomedical researchers.

Essentials of Laboratory Animal Science: Principles and Practices

Essentials of Laboratory Animal Science: Principles and Practices
Author: P. Nagarajan
Publisher: Springer Nature
Total Pages: 797
Release: 2021-07-23
Genre: Science
ISBN: 981160987X

This book comprehensively reviews the anatomy, physiology, genetics and pathology of laboratory animals as well as the principles and practices of using laboratory animals for biomedical research.It covers the design of buildings used for laboratory animals, quality control of laboratory animals, and toxicology, and discusses various animal models used for human diseases. It also highlights aspects, such as handling and restraint and administration of drugs, as well as breeding and feeding of laboratory animals, and provides guidelines for developing meaningful experiments using laboratory animals.Further, the book discusses various alternatives to animal experiments for drug and chemical testing, including their advantages over the current approaches. Lastly, it examines the potential effect of harmful pathogens on the physiology of laboratory animals and discusses the state of art in in vivo imaging techniques.The book is a useful resource for research scientists, laboratory animal veterinarians, and students of laboratory animal medicine.