Analytical Methods for PFAS in Products and the Environment

Analytical Methods for PFAS in Products and the Environment
Author: Schöpel, Miriam
Publisher: Nordic Council of Ministers
Total Pages: 105
Release: 2022-03-08
Genre: Science
ISBN: 9289372613

Available online: https://pub.norden.org/temanord2022-510/ Per- and polyfluoroalkyl substances (PFASs) are a large group of substances that have been widely used in articles since many years. They are found wherever extreme conditions prevail and particularly high demands are placed on materials. Their use spans over many different sectors ranging from fire-fighting foams to the manufacture of everyday articles like water-repellent outdoor jackets or stain-proofing agents.On the other side, PFASs are not easily degradable and can remain in the environment for decades. In addition, the use of PFASs has raised human and environmental concerns. In Europe, some PFASs are therefore classified as persistent, bioaccumulative and toxic (PBT) and very persistent and very bioaccumulative (vPvB) under the REACH Regulation. The following report provides an overview of currently available analytical methods for PFASs in different matrices.

Guide to Fluorine NMR for Organic Chemists

Guide to Fluorine NMR for Organic Chemists
Author: William R. Dolbier, Jr.
Publisher: John Wiley & Sons
Total Pages: 418
Release: 2016-08-24
Genre: Science
ISBN: 1118831098

Following its well-received predecessor, this book offers an essential guide to chemists for understanding fluorine in spectroscopy. With over 1000 compounds and 100 spectra, the second edition adds new data – featuring fluorine effects on nitrogen NMR, chemical shifts, and coupling constants. • Explains how to successfully incorporate fluorine into target molecules and utilize fluorine substituents to structurally characterize organic compounds • Includes new data on nitrogen NMR, focusing on N-15, to portray the influence of fluorine upon nitrogen NMR chemical shifts and coupling constants • Expands on each chapter from the first edition with additional data and updated discussion from recent findings • "The flawless ordering of material covered in this stand-alone volume is such that information can be found very easily." – Angewandte Chemie review of the first edition, 2010

Analyzing Biomolecular Interactions by Mass Spectrometry

Analyzing Biomolecular Interactions by Mass Spectrometry
Author: Jeroen Kool
Publisher: John Wiley & Sons
Total Pages: 402
Release: 2015-05-04
Genre: Science
ISBN: 3527334645

This monograph reviews all relevant technologies based on mass spectrometry that are used to study or screen biological interactions in general. Arranged in three parts, the text begins by reviewing techniques nowadays almost considered classical, such as affinity chromatography and ultrafiltration, as well as the latest techniques. The second part focusses on all MS-based methods for the study of interactions of proteins with all classes of biomolecules. Besides pull down-based approaches, this section also emphasizes the use of ion mobility MS, capture-compound approaches, chemical proteomics and interactomics. The third and final part discusses other important technologies frequently employed in interaction studies, such as biosensors and microarrays. For pharmaceutical, analytical, protein, environmental and biochemists, as well as those working in pharmaceutical and analytical laboratories.

Toxicological Effects of Perfluoroalkyl and Polyfluoroalkyl Substances

Toxicological Effects of Perfluoroalkyl and Polyfluoroalkyl Substances
Author: Jamie C. DeWitt
Publisher: Humana Press
Total Pages: 500
Release: 2015-04-14
Genre: Medical
ISBN: 3319155180

This book serves as a timely and comprehensive overview of the latest science for perfluoroalkyl and polyfluoroalkyl substances (PFASs), covering the development of methods for assessing PFASs in biological fluids and tissues as well as the current knowledge regarding their toxicity to vertebrate organisms. This book includes chapters on human and wildlife exposure/body burdens, reviews of metabolism and toxicological effects by organ system/developmental stage and aspects of PFAS toxicity that are driving PFAS research and regulatory oversight. Toxicological Effects of Perfluoroalkyl and Polyfluoroalkyl Substances provide critical assessments of the most controversial topics surrounding toxicological evaluation of PFASs to give readers an expert perspective on the issues. Emphasis is placed on the integration of modes and mechanisms of action with functional endpoints that are relevant to human and wildlife health. This book will be a useful resource for toxicologists, environmental chemists, risk assessors and researchers with an interest in the class of compounds known as perfluoroalkyl and polyfluoroalkyl substances.

The cost of inaction

The cost of inaction
Author: Gretta Goldenman
Publisher: Nordic Council of Ministers
Total Pages: 194
Release: 2019-03-17
Genre: Science
ISBN: 9289360658

PFAS (per and polyfluoroalkylsubstances) are known to be extremely difficult to degrade in the environment and to be bioaccumulative and toxic. Exposure to PFAS is suspected to increase the risk of adverse health effects, such as impacts on the thyroid gland, the liver, fat metabolism and the immune system. This study estimates the socioeconomic costs that may result from impacts on human health and the environment from the use of PFAS. Better awareness of the costs and problems associated with PFAS exposure will assist decision-makers and the general public to make more efficient and timely risk management decisions. Findings indicate that the costs are substantial, with annual health-related costs estimated to 2.8 – 4.6 billion EUR for the Nordic countries and 52 – 84 billion EUR for all EEA countries. Overall non-health costs are estimated at 46 million – 11 billion EUR for the Nordic countries.Upon request the excel spreadsheets used for the monetarisation and valuation in this report can also be provided along with a guidance on how to use the estimation of costs for value transfer. Please contact any of the consultants or members of the steering group from the Swedish Chemicals Agency or the Danish Environmental Protection Agency if you are interested in receiving these excel spreadsheets.

Analysis of needs for enforcement of PFAS in articles and chemical products

Analysis of needs for enforcement of PFAS in articles and chemical products
Author: Krause, Maren
Publisher: Nordic Council of Ministers
Total Pages: 191
Release:
Genre: Science
ISBN: 9289378018

Available online: https://pub.norden.org/temanord2024-510/ Per- and polyfluoroalkyl substances (PFAS) are a large group of substances that have been widely used for decades due to their surface-active properties. However, their characteristic resistance to degradation in combination with other properties of concern for human health and the environment has resulted in regulatory actions such as restrictions towards this group of substances, in the EU and globally. Compliance with restrictions as well as enforcement by authorities is key to reduce intentional use of restricted PFAS in articles and chemical products. To analyse PFAS accurately, robust and reliable analytical methods are required. This report evaluates the current situation related to PFAS-analyses and enforcement (including challenges and needs) and propose measures/strategies to enable and/or improve enforcement of, and compliance with current and future, PFAS restrictions.

PFASs in the Nordic environment

PFASs in the Nordic environment
Author: Anna Kärrman
Publisher: Nordic Council of Ministers
Total Pages: 156
Release: 2019-03-15
Genre: Technology & Engineering
ISBN: 9289360623

This report describes a screening study of in all ninety-nine conventional and emerging per- and polyfluoroalkyl substances (PFASs) in the Nordic environment. In addition, extractable organic fluorine (EOF) was analysed. The latter can provide the amount, but not identity, of organofluorine in the samples, which in turn can be used to assess the mass balance between known and unknown PFASs. The study was initiated by the Nordic Screening Group and funded by these and the Nordic Council of Ministers through the Chemicals Group.A total of 102 samples were analyzed in this study, including bird eggs, fish, marine mammals, terrestrial mammals, surface water, WWTP effluents and sludge, and air. Samples were collected by institutes from the participating countries and self-governing areas; Denmark, Faroe Islands, Finland, Greenland, Iceland, Norway, and Sweden.

Forever Chemicals

Forever Chemicals
Author: David M. Kempisty
Publisher: CRC Press
Total Pages: 361
Release: 2021-07-28
Genre: Technology & Engineering
ISBN: 1000405451

Forever Chemicals: Environmental, Economic, and Social Equity Concerns with PFAS in the Environment provides the reader with an understanding of the complex and interwoven issues associated with per- and polyfluorinated substances (PFAS) in our environment. The chapters provide in-depth perspective into various issues, including health, regulation, detection, clean-up strategies and technologies, and more. Taken together or as the reader’s interests lead them, the variety of topics covered in the book present a balanced perspective on this complex topic. It will address the current state of PFAS and where indicators are pointing for future developments. The book is also a deeper investigation of the regulatory challenges, analytical hurdles, and toxicological progress to date for the suite of PFAS chemicals. Features Explains the trends that will affect future policy and regulatory decisions Looks holistically at 4000+ PFAS chemicals Includes PFAS risk assessments at contaminated sites and biomonitoring insights Provides in-depth discussions on remediation technologies Illustrates quality and diversified content Provides a balanced perspective on this complex topic

Perfluoroalkyl Substances in the Environment

Perfluoroalkyl Substances in the Environment
Author: David M. Kempisty
Publisher: CRC Press
Total Pages: 498
Release: 2018-08-06
Genre: Science
ISBN: 0429945035

Per- and polyfluorinated alkyl substances (PFAS), often referred to as per- (and poly) fluorinated compounds (PFCs), have been used for years in many everyday3⁄4 and some lifesaving3⁄4 products. However, their use has been linked to adverse health effects in humans, a problem compounded by their persistence in the environment. This book discusses the various challenges of PFAS in our environment today, including their historical use as well as their chemical and toxicological properties. It also presents robust discussion of analytical challenges and special considerations in sampling. The work goes on to give practical recommendations for dealing with these compounds in today's dynamic regulatory landscape and includes several chapters on various remediation techniques. Key Features: Comprehensive overview of per- and polyfluorinated alkyl substances (PFAS) historical use and chemical/physical properties which help us understand their persistence, transport, and transformation pathways in the environment In-depth analysis of PFAS toxicology Detailed descriptions of conventional and state-of-the-art remediation technologies Practical recommendations for dealing with PFAS in a dynamic regulatory landscape Robust discussion of important sampling and analytical considerations Perfluoroalkyl Substances in the Environment: Theory, Practice, and Innovation explores the challenges across the topical areas of regulation and management, toxicology, environmental remediation, and analytical sampling and analysis.Readers will find this text helpful in understanding complexities associated with PFAS and informing management strategies to effectively protect this and future generations.

Fluorinated Surfactants and Repellents, Second Edition,

Fluorinated Surfactants and Repellents, Second Edition,
Author: Erik Kissa
Publisher: CRC Press
Total Pages: 650
Release: 2001-02-09
Genre: Science
ISBN: 9780824704728

A discussion of the synthesis, problems, theories and applications of fluorinated surfactants, this second edition is updated with four new chapters on repellency and protection against soiling and staining and over 2900 references, equations, and drawings (800 more than the previous edition). It lists alphabetically and explores numerous applications of fluorinated surfactants. Called "...a most useful introduction to these fascinating materials" by the Journal of Dispersion Science and Technology and "...a coherent and stimulating handbook...the most useful book in the fluorinated surfactants field to date. Recommended." by the Journal of the Chemical Society, Faraday Transactions - this book is a source of factual data, methods of manufacture, and chemical structures for the surfactant scientist and user.