The COVID-19 pandemic continued to spread in 2022. However, with the increasing distribution of vaccines and the emergence of less severe viral variants, the Ministry of Health and Welfare changed its focus from a strict containment epidemic prevention policy to a strategic policy of coexistence. Drawing upon the wealth of experience and adaptability gained from past challenges, we progressively embarked on a path towards easing pandemic restrictions. Furthermore, guided by our vision to be "the most trustworthy ministry for the people," we remained committed to continuously elevating healthcare professionalism, integrating and effectively allocating social welfare resources, and aligning ourselves with the global health and welfare system. Aging and low birth rates remain the most pressing issues facing Taiwan's population. The Ministry continues to create a friendly parenting environment, providing ongoing assistance for infertility treatment, increasing child-raising allowance, and daycare subsidies to alleviate the child-rearing burden on families. In April 2022, we expanded the nationwide "Home Care Program for Low (including extremely low) Birth Weight Infants" to enhance the quality of care. On the other hand, in response to an aged society, the Ministry is actively promoting age-friendly and dementia-friendly environments. By the end of 2022, a total of 585 locations were established in various counties and cities, offering health promotion courses for the elderly to ensure comprehensive and sustained healthcare services. We also funded 40 community nutrition promotion centers and branch centers nationwide, supporting communal dining venues and community food service providers to offer age-friendly dining services. Our efforts further expanded to dementia prevention and friendly community initiatives, implementing policies to "enhance public awareness and friendly attitudes towards dementia" and "reduce the risk of developing dementia." In addition to safeguarding not only the elderly and young but also every individual across their entire lifespan, we have been diligently cultivating a health-supportive environment. To this end, the Ministry continues to drive amendments to the Tobacco Hazards Prevention Act, effectively regulating novel nicotine and tobacco products. Simultaneously, under the provisions of the Mental Health Act, we ensure the protection of patients' rights, offering support and assistance to foster their integration into the community and promote the mental well-being of the people. Furthermore, through the comprehensive implementation of the "Five-Point Food Safety Policy" and a range of measures, such as the promotion of food business registration, intensified inspections and sampling, and more stringent penalties, we have steadfastly enforced food safety policies. At the same time, we have taken great strides in advancing Good Manufacturing Practices for pharmaceuticals, bolstering the monitoring of controlled drugs, and elevating the quality management standards of traditional Chinese medicines, thereby fortifying the foundations of medication safety. In 2022, the "Review Meeting of the ROC's Second Report under the Convention on the Rights of Persons with Disabilities" in August and the "Review Meeting of the ROC's Second Report under the Convention on the Rights of the Child" in November, were held in Taiwan and the international experts were invited to review the reports. Their expertise promoted the effective implementation of these conventions in Taiwan, while the invaluable insights from diverse stakeholders were warmly embraced. We analyzed global pandemic trends while considering both epidemic resilience and economic activities. The Ministry continues to promote COVID-19 vaccination, providing bivalent second-generation vaccines to the public. We have implemented rolling adjustments to border quarantine and control measures. Residential and community-based care institutions are provided with free rapid test kits, and regular screening measures have been extended to reduce infection risks for vulnerable and high-risk populations. To strengthen economic security, we have increased subsidies for low-income and middle-low-income households, benefiting over 620,000 people. With the goal of "normalcy in daily life, proactive epidemic prevention, and stable opening," we have adjusted the home quarantine close contacts, moderately relaxed mask regulations, and reduced restrictions on hospital visits, gradually moving towards a phased reopening of daily life. The 75th World Health Assembly (WHA) was convened in Geneva, Switzerland, in May 2022. Although Taiwan was not invited to participate in the WHA, MOHW Deputy Minister Li-Feng Lee led the "WHA Action Team" to Geneva. Through hosting professional forums, bilateral meetings, and engaging in related side events, we have continued deepening our collaborative relationships with various countries and international organizations in health. All this serves to convey to the international community Taiwan's determination to persistently engage in international health affairs with professionalism, pragmatism, and a commitment to contribute to international health affairs. To enhance international cooperation and exchange, Taiwan joined the Vaccination Credential Initiative (VCI) led by the United States in May 2022. The MOHW can issue digital vaccination certificates in Smart Health Card (SHC) format that can be certified. Furthermore, the MOHW continues promoting the New Southbound Policy in Healthcare. Based on country risk and different cooperation development of the NSP priority countries with Taiwan, additional centers were established in Vietnam, Malaysia, and Indonesia, expanding the "7 Countries, 7 Centers" to "7 Countries, 10 Centers" program and promoting the internationalization of Taiwan's healthcare industry. As the COVID-19 policy moves towards coexistence and people's lives gradually return to normalcy after the pandemic, the Ministry will continue to prioritize the care for vulnerable groups and improve the welfare service system. We are committed to establishing and perfecting long-term care systems and service resources, optimizing protection services, fostering a harmonious and supportive society, expanding the healthcare system, and safeguarding the rights and interests of the public in seeking medical care. Our mission is to ensure a safe and secure environment for food and drugs and to enhance the health and well-being of the people in Taiwan.