Ageless Quest

Ageless Quest
Author: Leonard Guarente
Publisher: CSHL Press
Total Pages: 172
Release: 2003
Genre: Family & Relationships
ISBN: 9780879696528

Ageless Questis a personal, sometimes controversial, account of the pursuit of a genetic †̃cure' for aging by an expert in the field. The author is the Novartis Professor of Biology at the Massachusetts Institute of Technology. Aging has always been regarded as a highly complex process with many degenerative changes leading to the cessation of life. But recent research has identified a relatively simple mechanism that governs the pace of aging. Lenny Guarente's Ageless Questis a scientific detective story for the baby boom generation. It offers an insider's view of an area of potentially astonishing high reward—and equally high risk.

The Quest for Human Longevity

The Quest for Human Longevity
Author: Lewis D. Solomon
Publisher: Routledge
Total Pages: 220
Release: 2017-12-02
Genre: Political Science
ISBN: 1351475592

"Many scientists today are working to retard the aging process in humans so as to increase both life expectancy and the quality of life. Over the past decade impressive results have been achieved in targeting the mechanisms and pathways of aging. In The Quest for Human Longevity, Lewis D. Solomon considers these scientific studies by exploring the principal biomedical anti-aging techniques. The book also considers cutting edge research on mental enhancements and assesses the scientific doubts of skeptics. The Quest for Human Longevity is also about business. Solomon examines eight corporations pursuing various age-related interventions, profiling their scientific founders and top executives, and examining personnel, intellectual property, and financing for each firm. Academic scientists form the link between research and commerce. Solomon notes that the involvement of university scientists and researchers follows one of two models. The first is a traditional model in which scientists leave academia to work for a corporation or remain in academia and obtain business support for their research. The second is a modern model in which scientists use their intellectual property as a catalyst for acquiring equity interests in the firms they organize. Critics have pointed to the dangers of commercialized science, but Solomon's analysis, on balance, finds that the benefits outweigh the costs and that problems of secrecy and conflicts of interest can be addressed. If scientists succeed in unlocking the secrets of aging and developing drugs or therapies that will allow us to live decades longer, the consequences for society will include profound social, political, economic, and ethical questions. Solomon deals with the public policy aspects of significant life extension and looks at the conflict between those who advocate the acceptance of mortality and the partisans of life. The Quest for Human Longevity will be of interest to policymakers, sociologists, scientists, and studen"

Ageless

Ageless
Author: Andrew Steele
Publisher: Anchor
Total Pages: 353
Release: 2021-03-23
Genre: Science
ISBN: 0385544936

“A fascinating look at how scientists are working to help doctors treat the aging process itself, helping us all to lead longer, healthier lives.” —Sanjay Gupta, MD Aging—not cancer, not heart disease—is the underlying cause of most human death and suffering. The same cascade of biological changes that renders us wrinkled and gray also opens the door to dementia and disease. We work furiously to conquer each individual disease, but we never think to ask: Is aging itself necessary? Nature tells us it is not: there are tortoises and salamanders who are spry into old age and whose risk of dying is the same no matter how old they are, a phenomenon known as “biological immortality.” In Ageless, Andrew Steelecharts the astounding progress science has made in recent years to secure the same for humans: to help us become old without getting frail, to live longer without ill health or disease.

How We Age

How We Age
Author: Coleen T. Murphy
Publisher: Princeton University Press
Total Pages: 464
Release: 2023-11-14
Genre: Science
ISBN: 0691182639

How recent breakthroughs in longevity research offer clues about human aging All of us would like to live longer, or to slow the debilitating effects of age. In How We Age, Coleen Murphy shows how recent research on longevity and aging may be bringing us closer to this goal. Murphy, a leading scholar of aging, explains that the study of model systems, particularly simple invertebrate animals, combined with breakthroughs in genomic methods, have allowed scientists to probe the molecular mechanisms of longevity and aging. Understanding the fundamental biological rules that govern aging in model systems provides clues about how we might slow human aging, which could lead in turn to new therapeutics and treatments for age-related disease. Among other vivid examples, Murphy describes research that shows how changing a single gene in the nematode worm C. elegans doubles its lifespan, extending not only the end of life but also the youthful, healthy part of life. Drawing on work in her own lab as well as other recent research, Murphy chronicles the history and current state of the field, explaining longevity’s links to reproduction and mating, sensory and cognitive function, inheritances from our ancestors, and the gut microbiome. Written with clarity and wit, How We Age provides a guide to the science: what we know about aging, how we know what we know, and what we can do with this new knowledge.

The Long Tomorrow

The Long Tomorrow
Author: Michael R. Rose
Publisher: Oxford University Press
Total Pages: 189
Release: 2005-09-15
Genre: Family & Relationships
ISBN: 0195179390

Equally important, Rose surveys the entire field, offering colorful portraits of many leading scientists and shedding light on research findings from around the world. We learn that rodents given fifteen to forty percent fewer calories live about that much longer, and that volunteers in Biosphere II, who lived on reduced caloric intake for two years, all had improved vital signs. Perhaps most interesting, we discover that aging hits a plateau and stops - at least, it does so in fruit flies."--Jacket.

The Book of Immortality

The Book of Immortality
Author: Adam Gollner
Publisher: Simon and Schuster
Total Pages: 416
Release: 2014-09-30
Genre: Health & Fitness
ISBN: 1439109435

An exploration of one of the most universal human obsessions charts the rise of longevity science from its alchemical beginnings to modern-day genetic interventions and enters the world of those whose lives are shaped by a belief in immortality.

Spring Chicken

Spring Chicken
Author: Bill Gifford
Publisher: Hachette+ORM
Total Pages: 311
Release: 2016-08-02
Genre: Self-Help
ISBN: 1455527459

From acclaimed journalist Bill Gifford comes a roaring journey into the world of anti-aging science in search of answers to a universal obsession: what can be done about getting old? Spring Chicken: Stay Young Forever (or Die Trying) Spring Chicken is a full-throttle, high-energy ride through the latest research, popular mythology, and ancient wisdom on mankind's oldest obsession: How can we live longer? And better? In his funny, self-deprecating voice, veteran reporter Bill Gifford takes readers on a fascinating journey through the science of aging, from the obvious signs like wrinkles and baldness right down into the innermost workings of cells. We visit cutting-edge labs where scientists are working to "hack" the aging process, like purging "senescent" cells from mice to reverse the effects of aging. He'll reveal why some people live past 100 without even trying, what has happened with resveratrol, the "red wine pill" that made headlines a few years ago, how your fat tissue is trying to kill you, and how it's possible to unlock longevity-promoting pathways that are programmed into our very genes. Gifford separates the wheat from the chaff as he exposes hoaxes and scams foisted upon an aging society, and arms readers with the best possible advice on what to do, what not to do, and what life-changing treatments may be right around the corner. An intoxicating mixture of deep reporting, fascinating science, and prescriptive takeaway, Spring Chicken will reveal the extraordinary breakthroughs that may yet bring us eternal youth, while exposing dangerous deceptions that prey on the innocent and ignorant.

Jake

Jake
Author: Arch Montgomery
Publisher: Bancroft Press
Total Pages: 234
Release: 2004-06
Genre: Juvenile Nonfiction
ISBN: 1610880560

Jake takes place during one of the single most powerfully shaping times in a person's lifesecondary education. Through the metaphor of the utopian and fictitious St. Stephen's Episcopal School, author Arch Montgomery shows us how our humanity can only be fully realized through other humans. The book depicts three deaths and one near-fatal disease while simultaneously tracking the rebirth of Jake, the titular and main character. He moves from a transparent only-good-as-I-have-to-be mentality to a lifestyle of excellence and three-dimensionality with the help of his school, which is personified through the characters of Mary White, rector; George Meader, teacher; and Joel Kohn, student. Jake presents both Montgomery's view of public school systems (which Jake, without a drop of nostalgia, refers to as out in the county) and his view of an ideal school, which, in this case, comes in the form of an independent school, though the tenets that make it so admirable could be applied to almost any schoolpublic, independent, parochial, or otherwise. Mixing real-world models with an informed idealism, Montgomery creates St.Stephen's in order to demonstrate the most positive influence a school can have on one person. On the flipside of that coin, however, remain numerous questions about what kind of negative effects sub-par schools can have on their students. While St. Stephen's gives its students a three-dimensional educationmind (academics), body (athletics), and spirit (chapel and community ervice)do public schools scratch the surface of even just one dimension? While Mary White, the head of St. Stephen's, plays roles as varied as disciplinarian, spiritual leader, and friend, in what light do most public school students view their own principals? While the educational events of the highest consequence happen to Jake outside the classroom, how many public school students interact with their classmates, teachers, or administration beyond a school setting? On a continuum of education qualitysatisfactory, good, great, excellent, idealwhere does St. Stephen's fall? Where does the school you went to, or your children go to, fall? These and many other questions arise in Jake, and beg to be discussed, because once problems are recognized, they can begin to get solved.

The Longevity Factor

The Longevity Factor
Author: Joseph Maroon
Publisher: Simon and Schuster
Total Pages: 370
Release: 2008-12-30
Genre: Health & Fitness
ISBN: 1416551077

Neuroscientist and surgeon Joseph Maroon looks at recent scientific breakthroughs identifying a group of natural substances--including the much-publicized molecule resveratrol--that can actually activate a specific set of genes that promote a longer, healthier life. These substances, which make red wine, dark chocolate, and green tea good for us, appear to stave off a wide array of age-related diseases and keep us feeling young and vital. Only recently have scientists discovered how to isolate resveratrol and concentrate it into an affordable and safe supplement. Already, more than 200 supplements featuring resveratrol have flooded the market, and there are more on the way. What is a consumer to look for? Since resveratrol is a natural substance, can you get enough of it through diet alone, or should you combine diet with a supplement? And what lies on the horizon from the pharmaceutical industry? These questions and many more are answered here. --From publisher description.