Genetic Dissection of Complex Traits

Genetic Dissection of Complex Traits
Author: D.C. Rao
Publisher: Academic Press
Total Pages: 788
Release: 2008-04-23
Genre: Medical
ISBN: 0080569110

The field of genetics is rapidly evolving and new medical breakthroughs are occuring as a result of advances in knowledge of genetics. This series continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines. Five sections on the latest advances in complex traits Methods for testing with ethical, legal, and social implications Hot topics include discussions on systems biology approach to drug discovery; using comparative genomics for detecting human disease genes; computationally intensive challenges, and more

Homology Effects

Homology Effects
Author:
Publisher: Elsevier
Total Pages: 565
Release: 2002-04-02
Genre: Science
ISBN: 0080490328

Homology Effects offers contributions from an international panel of researchers whose aim has been both to introduce newcomers to the field of homology effects, and to bring colleagues up to date. Topic coverage includes dosage compensation, X-inactivation, imprinting, paramutation, homology-dependent gene silencing, transvection, pairing-sensitive silencing, nuclear organization of chromosomes, DNA repair, quelling, RIP, RNAi and antisense biology, homology effects in ciliates, prion biology, and a discourse on the evolution of gene duplications. Advances in Genetics presents an eclectic mix of articles of use to all human and molecular geneticists. They are written and edited by recognized leaders in the field and make this an essential series of books for anyone in the genetics field. - Homology, the examination of similarity due to shared common ancestry, encompasses a fascinating class of phenomena in mammals, plants, insects, ciliates, nematodes, fungi, and bacteria. Homology effects concern processes that recognize homology at the level of DNA and/or RNA, as well as at the level of protein. Their collective history begins at the turn of the century and includes some of the most puzzling and extraordinary observations in biology. The volume covers phenomena that have often been considered unusual, exceptional to the rule, and "out of the ordinary" and, therefore, not for general study. However, it is now becoming clear that taken together, these phenomena represent a class of regulatory mechanisms that are widespread, as well as exceptionally powerful.

Advances in Gene Technology: Molecular Genetics of Plants and Animals

Advances in Gene Technology: Molecular Genetics of Plants and Animals
Author: Kathleen Downey
Publisher: Elsevier
Total Pages: 636
Release: 2013-10-22
Genre: Science
ISBN: 1483100022

Advances in Gene Technology: Molecular Genetics of Plants and Animals contains the proceedings of the Miami Winter Symposium held in January 1983 in Miami, Florida. The papers explore advances in the molecular genetics of plants and animals and cover a wide range of topics such as genetic manipulation of plants; plant cell cultures, regeneration, and somatic cell fusion; and nitrogen fixation. Practical applications of gene technology with plants are also discussed. Comprised of 84 chapters, this volume begins with an overview of how plants manufacture from carbon dioxide and water all of their substances, paying particular attention to the path of carbon in photosynthesis. The organization of the plant genome is then considered, along with techniques for cell culture, regeneration, and somatic cell fusion; vector systems; and nitrogen fixation. Some chapters focus on gene transfer by protoplast fusion; somatic cell genetic systems in corn; regulation of transcription of the nitrogen fixation operons; and leghemoglobin and nodulin genes of soybean. The final section is devoted to practical applications of gene technology to plants and to technology frontiers in animal biology, in particular embryonic development and vaccines and diagnostic methods for animal diseases. This book should be of value to molecular geneticists.

Cosmic Genetic Evolution

Cosmic Genetic Evolution
Author:
Publisher: Academic Press
Total Pages: 164
Release: 2020-10-18
Genre: Science
ISBN: 0128215259

Cosmic Genetic Evolution, Volume 106 in the Advances in Genetics series, highlights new advances in the field, with this new volume presenting interesting chapters on Panspermia, Cometary Panspermia and Origin of Life, The Efficient Lamarckian Spread of Life in the Cosmos, The Sociology of Science and Generality of the DNA/RNA/Protein Paradigm Throughout the Cosmos, The Mutagenic Source and Power of Our Own Evolution, Origin of New Emergent Coronavirus and Candida Fungal Diseases – Terrestrial or Cosmic?, and Future Prospects for Investigation -The Near-Earth Neighborhood and Beyond. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Advances in Genetics series - Updated release includes the latest information on the Cosmic Genetic Evolution

Socio-Genetics

Socio-Genetics
Author:
Publisher: Academic Press
Total Pages: 123
Release: 2009-11-12
Genre: Science
ISBN: 008095393X

Socio-Genetics seeks to understand both the genetic and environmental contributions to individual variations in behavior. Behaviors, like all complex traits, involve multiple genes, a reality that complicates the search for genetic contributions. As with much other research in genetics, studies of genes and behavior require analysis of families and populations for comparison of those who have the trait in question with those who do not. The result commonly is a statement of "heritability," a statistical construct that estimates the amount of variation in a population that is attributable to genetic factors. The explanatory power of heritability figures is limited, however, applying only to the population studied and only to the environment in place at the time the study was conducted. If the population or the environment changes, the heritability most likely will change as well. Focused on the genetics of complex traits in a variety of organisms—honeybees, mice, and nematodes—this volume discusses environmental influence on genetic programs and evolutionary genetics. Such research is proving important in furthering our understanding of the genetic basis of such diseases as obesity, schizophrenia, multiple sclerosis, and autism, to name a few. - Most recent research findings on gene-environment interaction and complex behavior, allows researchers to make predictions about the genetic mechanisms that underlie some basic behaviors—eating, for example—leading to new and novel treatments for some genetically based abnormal behaviors - Reviews environmental programming of phenotypic diversity in female reproductive strategies, providing important insight into fertility and in developing therapeutic strategies to treat infertility

Advances in Genetics, Genomics and Control of Rice Blast Disease

Advances in Genetics, Genomics and Control of Rice Blast Disease
Author: Xiaofan Wang
Publisher: Springer Science & Business Media
Total Pages: 433
Release: 2009-03-01
Genre: Technology & Engineering
ISBN: 1402095007

Rice blast, caused by the fungal pathogen Magnaporthe grisea, is one of the most destructive rice diseases worldwide and destroys enough rice to feed more than 60 million people annually. Due to high variability of the fungal population in the field, frequent loss of resistance of newly-released rice cultivars is a major restraint in sustainable rice production. In the last few years, significant progress has been made in understanding the defense mechanism of rice and pathogenicity of the fungus. The rice blast system has become a model pathosystem for understanding the molecular basis of plant-fungal interactions due to the availability of both genomes of rice and M. grisea and a large collection of genetic resources. This book provides a complete review of the recent progress and achievements on genetic, genomic and disease control of the disease. Most of the chapters were presented at the 4th International Rice Blast Conference held on October 9-14, 2007 in Changsha, China. This book is a valuable reference not only for plant pathologists and breeders working on rice blast but also for those working on other pathysystems in crop plants.

Fungal Genomics

Fungal Genomics
Author: Jay C. Dunlap
Publisher: Elsevier
Total Pages: 316
Release: 2011-07-29
Genre: Science
ISBN: 0080474950

The sequencing of several fungi genomes has spurred major advances in the field. Fungal genomics has been having a pivotal impact on applied research in agriculture, food sciences, natural resource management, pharmaceuticals, and biotechnology, as well as to basic studies in the life sciences. Fungal Genomics covers exciting new developments in this growth field, from genomic analysis to human fungal pathogen genomics, comparative genomics of fungi, and the genomics of fungal development. - Includes information on aspergillus genomes - Discusses sex and its role in virulence of human fungal pathogens - Covers the genomic analysis of neurospora

Aggression

Aggression
Author:
Publisher: Academic Press
Total Pages: 307
Release: 2011-11-09
Genre: Technology & Engineering
ISBN: 0123808596

Genes interact with the environment, experience, and biology of the brain to shape an animal's behavior. This latest volume in Advances in Genetics, organized according to the most widely used model organisms, describes the latest genetic discoveries in relation to neural circuit development and activity. - Explores the latest topics in neural circuits and behavior research in zebrafish, drosophila, C.elegans, and mouse models - Includes methods for testing with ethical, legal, and social implications - Critically analyzes future prospects

Advanced Molecular Genetics

Advanced Molecular Genetics
Author: Alfred Pühler
Publisher: Springer Science & Business Media
Total Pages: 353
Release: 2012-12-06
Genre: Science
ISBN: 3642693059

The development of powerful new techniques and refmements of tech niques in molecular genetics in recent years, and the surge in interest in biotechnology based on genetic methods, have heralded a new golden age in molecular genetics, and stimulated in diverse disciplines much interest in the technologies themselves and their potential uses in basic and applied biomedical sciences. Although some excellent specialist laboratory manuals (especially the Cold Spring Harbor Laboratory manuals by I. H. Miller; R. W. Davies et al. ; and T. Maniatis et al. ) on certain chapters of molecular genetics exist, no general text that covers a broad spectrum of the sub ject has thus far been published. The purpose of this manual is to pre sent most, though of necessity not all of the important methods of molecular genetics, in a series of simple experiments, many of which can be readily accomplished by the microbiologist, biochemist or biotechnologist that has had only limited exposure to genetics. The remainder of the experiments require either greater familiarity with the subject, or guidance by someone with such experience. The book should, therefore, not only enable individuals to acquire new proce dures for ongoing projects, but also serve as a basis for the teaching of molecular genetic techniques in formal predoctoral and postdoctoral laboratory courses.

From Genetics to Mathematics

From Genetics to Mathematics
Author: Miroslaw Lachowicz
Publisher: World Scientific
Total Pages: 242
Release: 2009
Genre: Science
ISBN: 9812837256

This volume contains pedagogical and elementary introductions to genetics for mathematicians and physicists as well as to mathematical models and techniques of population dynamics. It also offers a physicist''s perspective on modeling biological processes. Each chapter starts with an overview followed by the recent results obtained by authors. Lectures are self-contained and are devoted to various phenomena such as the evolution of the genetic code and genomes, age-structured populations, demography, sympatric speciation, the Penna model, Lotka-Volterra and other predator-prey models, evolutionary models of ecosystems, extinctions of species, and the origin and development of language. Authors analyze their models from the computational and mathematical points of view.