The book reports on the latest theoretical and experimental findings in the field of active flow and combustion control, in the context of energy conversion for power and propulsion systems. It covers new developments in actuator technology and sensing, robust and optimal open- and closed-loop control, model reduction for control purposes, and unsteady turbine cooling and performance, among other relevant topics. Gathering contributions to the Active Flow and Combustion Control (AFCC 2021), held virtually on September 28-29, 2021, from the Technische Universität Berlin, Germany, this book describes research that has been carried out within, and supported by, the collaborative research center SFB 1029 on “Substantial efficiency increase in gas turbines through direct use of coupled unsteady combustion and flow dynamics”, and funded by the German Research Foundation (DFG). It highlights theoretical and practical aspects, and corresponding solutions, that are important for the development of future energy conversion systems, thus offering a timely guide for researchers and practitioners in the field of aeronautics, turbomachinery, control and combustion.