A Toxicologist's Guide to Clinical Pathology in Animals

A Toxicologist's Guide to Clinical Pathology in Animals
Author: John E. Whalan
Publisher: Springer
Total Pages: 165
Release: 2015-03-25
Genre: Medical
ISBN: 3319158538

This guide provides an easy-to-use desk reference for diagnostic information on commonly used hematology, clinical chemistry and urinalysis parameters. Additional reference materials are provided as an aid in evaluating clinical pathology data. For many toxicologists, the evaluation of hematology, clinical chemistry and urinalysis data can be the most challenging aspect of animal toxicity studies. In a typical toxicity study, dozens of parameters are measured several times over the course of the study. There may be hundreds of data points, each of which needs to be considered. A Toxicologist’s Guide to Clinical Pathology in Animals will serve as an essential primer for toxicologists in training and in industry as well as for researchers and professionals in a veterinary practice or a laboratory.

Animal Hematotoxicology

Animal Hematotoxicology
Author: G.O. Evans
Publisher: CRC Press
Total Pages: 222
Release: 2008-07-25
Genre: Medical
ISBN: 1420080105

Hematology data from in vivo toxicology studies remains one of the most predictive measures for human risk, as the same measurements made in pre-clinical toxicology studies can be made in early clinical trials. Covering the three main blood cell types - erythrocytes, leukocytes and thrombocytes, this work is designed to clarify topics fo

Pathology for Toxicologists

Pathology for Toxicologists
Author: Elizabeth McInnes
Publisher: John Wiley & Sons
Total Pages: 214
Release: 2017-03-24
Genre: Science
ISBN: 1118755308

Non-pathologists, such as toxicologists and study personnel, can find it difficult to understand the data they receive from pathologists. Toxicological pathologists write long, detailed and highly technical reports. Study personnel are under daily pressure to decide whether lesions described in pathology reports are treatment-related and thus important to the pharmaceutical company or whether the lesions are background changes and thus of little significance. Written by experienced toxicological pathologists, Pathology for Toxicologists: Principles and Practices of Laboratory Animal Pathology for Study Personnel serves to bridge the gap in the understanding of pathology data, enabling non-pathologists to more easily comprehend pathology reports, better integrate pathology data into final study reports and ask pathologists relevant questions about the test compound. This succinct, fully referenced, full colour book is suitable for toxicologists at all stages of their training or career who want to know more about the pathology encountered in laboratory animals used in safety studies. Key features include important chapters on spontaneous and target organ lesions in rats, mice, non-human primates, mini pigs, rabbits and beagle dogs as well as information on general pathology, macroscopic target organ lesions, ancillary pathology techniques, haematology, biochemistry and adversity. Pathology for Toxicologists: Principles and Practices of Laboratory Animal Pathology for Study Personnel includes: Colour diagrams explaining how lesions are caused by either external compounds or spontaneously The anatomic variations and background lesions of laboratory animals Advice on sampling tissues, necropsy, ancillary pathology techniques and recording data A chapter on the haematology and biochemistry of laboratory animals Full colour photographs of common macroscopic lesions encountered in laboratory animals A comprehensive glossary

Fundamentals of Toxicologic Pathology

Fundamentals of Toxicologic Pathology
Author: Matthew A. Wallig
Publisher: Academic Press
Total Pages: 714
Release: 2009-11-23
Genre: Medical
ISBN: 0080919324

Toxicologic pathology integrates toxicology and the disciplines within it (such as biochemistry, pharmacodynamics and risk assessment) to pathology and its related disciplines (such as physiology, microbiology, immunology, and molecular biology). Fundamentals of Toxicologic Pathology Second Edition updates the information presented in the first edition, including five entirely new chapters addressing basic concepts in toxicologic pathology, along with color photomicrographs that show examples of specific toxicant-induced diseases in animals. The current edition also includes comparative information that will prove a valuable resource to practitioners, including diagnostic pathologists and toxicologists. 25% brand new information, fully revised throughout New chapters: Veterinary Diagnostic Toxicologic Pathology; Clinical Pathology; Nomenclature: Terminology for Morphologic Alterations; Techniques in Toxicologic Pathology New color photomicrographs detailing specific toxicant-induced diseases in animals Mechanistic information integrated from both toxicology and pathology discussing basic mechanisms of toxic injury and morphologic expression at the subcellular, cellular, and tissue levels

Clinical Pathology for the Veterinary Team

Clinical Pathology for the Veterinary Team
Author: Andrew J. Rosenfeld
Publisher: John Wiley & Sons
Total Pages: 304
Release: 2011-11-28
Genre: Medical
ISBN: 111827556X

Clinical Pathology for the Veterinary Team is a concise, reliable resource for technical team members performing clinical diagnostic evaluation. Focusing on sample handling, machinery calibration, normal physiology and anatomy, clinical diagnostics, and disease processes, this essential bench-side reference for in-house laboratories helps technical team members to consistently achieve high-quality results in small animal lab work. With chapters on blood counts, chemistry, urinalysis and electrolytes, advanced diagnostics, and cytology, Clinical Pathology for the Veterinary Team offers key technical information for consistently obtaining and evaluating samples. The book is a practical resource for anyone performing lab work, including veterinary technicians, technician and veterinary students, and veterinarians.

Animal Clinical Chemistry

Animal Clinical Chemistry
Author: G.O. Evans
Publisher: CRC Press
Total Pages: 230
Release: 1996-04-29
Genre: Medical
ISBN: 113574551X

By presenting background information on the selection and application of biochemical tests in safety assessment studies, this text seeks to provide a basis for improving the knowledge required to interpret data from toxicological studies. In addition to chapters which discuss the assessment of specific organ toxicity (such as the liver, kidney and

Veterinary Clinical Pathology Secrets E-Book

Veterinary Clinical Pathology Secrets E-Book
Author: Rick L. Cowell
Publisher: Elsevier Health Sciences
Total Pages: 408
Release: 2004-06-30
Genre: Medical
ISBN: 1437711480

Part of the popular SECRETS SERIES®, this all-new text provides essential, practical information for reviewing pathology commonly encountered in clinical situations. Organized by disorder type, it features numerous photos, a popular question-and-answer format, and a detailed index that makes it easy to find information quickly. In more than 50 chapters, expert contributors propose key questions and provide authoritative answers addressing the situations that confront small animal veterinarians every day. Comprehensive coverage of pathology is offered by a team of nationally recognized veterinary pathology experts. All of the most important "need to know" questions and answers are provided in the proven format of the acclaimed Secrets Series. More than 150 superior-quality photos highlight key concepts. A thorough, highly detailed index provides quick and easy access to specific topics.

Clinical Pathology for the Veterinary Team

Clinical Pathology for the Veterinary Team
Author: Andrew J. Rosenfeld
Publisher: John Wiley & Sons
Total Pages: 304
Release: 2010-07-13
Genre: Medical
ISBN: 0813810086

Clinical Pathology for the Veterinary Team is a concise, reliable resource for technical team members performing clinical diagnostic evaluation. Focusing on sample handling, machinery calibration, normal physiology and anatomy, clinical diagnostics, and disease processes, the book helps technical team members to consistently achieve high-quality results in small animal lab work. An essential bench-side reference for in-house laboratories, the book includes a DVD with interactive cases to build skills in reading and interpreting digital slides. With chapters on blood counts, chemistry, urinalysis and electrolytes, advanced diagnostics, and cytology, Clinical Pathology for the Veterinary Team offers key technical information for consistently obtaining and evaluating samples. The book is a practical resource for anyone performing lab work, including veterinary technicians, technician and veterinary students, and veterinarians.

Fundamentals of Veterinary Clinical Pathology

Fundamentals of Veterinary Clinical Pathology
Author: Steven L. Stockham
Publisher: John Wiley & Sons
Total Pages: 948
Release: 2013-05-31
Genre: Medical
ISBN: 1118686071

This book provides in-depth information about common clinical laboratory assays that are used to evaluate domestic mammals, including what assays measure, sample or assay conditions that affect results, and what results indicate about the physiologic or pathologic state of a patient. Whenever possible, diseases and conditions are grouped by common mechanisms or processes to promote a conceptual understanding of laboratory data that can be generally applied across many species. New to the second edition are additional disorders, diagnostic tests, illustrations, images, references, and pathophysiologic explanations. This text has proven valuable to students and veterinarians wanting a fundamental understanding of veterinary clinical pathology.

Clinical Pathology and Laboratory Techniques for Veterinary Technicians

Clinical Pathology and Laboratory Techniques for Veterinary Technicians
Author: Anne M. Barger
Publisher: John Wiley & Sons
Total Pages: 280
Release: 2015-08-24
Genre: Medical
ISBN: 111877468X

Clinical Pathology and Laboratory Techniques for Veterinary Technicians provides a comprehensive reference of laboratory procedures featuring ‘how-to’ information as it pertains to small animals, horses, and cattle. An inclusive reference on laboratory procedures pertaining to small animals, horses and cattle Provides information on hematology, hemostasis, clinical chemistry, urinalysis, parasitology, and fecal testing Features high-quality photographs labelled with magnification and stain information, which clearly depict cellular morphology, inclusions and infectious organisms Offers key objectives, technician tip boxes, case examples and a glossary of key terms A companion website provides images from the book for download, instructor questions and answer key to multiple choice questions in the book