A Primer On Experiments With Mixtures
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| Author | : John A. Cornell |
| Publisher | : John Wiley & Sons |
| Total Pages | : 376 |
| Release | : 2011-09-26 |
| Genre | : Mathematics |
| ISBN | : 0470907428 |
The concise yet authoritative presentation of key techniques for basic mixtures experiments Inspired by the author's bestselling advanced book on the topic, A Primer on Experiments with Mixtures provides an introductory presentation of the key principles behind experimenting with mixtures. Outlining useful techniques through an applied approach with examples from real research situations, the book supplies a comprehensive discussion of how to design and set up basic mixture experiments, then analyze the data and draw inferences from results. Drawing from his extensive experience teaching the topic at various levels, the author presents the mixture experiments in an easy-to-follow manner that is void of unnecessary formulas and theory. Succinct presentations explore key methods and techniques for carrying out basic mixture experiments, including: Designs and models for exploring the entire simplex factor space, with coverage of simplex-lattice and simplex-centroid designs, canonical polynomials, the plotting of individual residuals, and axial designs Multiple constraints on the component proportions in the form of lower and/or upper bounds, introducing L-Pseudocomponents, multicomponent constraints, and multiple lattice designs for major and minor component classifications Techniques for analyzing mixture data such as model reduction and screening components, as well as additional topics such as measuring the leverage of certain design points Models containing ratios of the components, Cox's mixture polynomials, and the fitting of a slack variable model A review of least squares and the analysis of variance for fitting data Each chapter concludes with a summary and appendices with details on the technical aspects of the material. Throughout the book, exercise sets with selected answers allow readers to test their comprehension of the material, and References and Recommended Reading sections outline further resources for study of the presented topics. A Primer on Experiments with Mixtures is an excellent book for one-semester courses on mixture designs and can also serve as a supplement for design of experiments courses at the upper-undergraduate and graduate levels. It is also a suitable reference for practitioners and researchers who have an interest in experiments with mixtures and would like to learn more about the related mixture designs and models.
| Author | : John A. Cornell |
| Publisher | : John Wiley & Sons |
| Total Pages | : 682 |
| Release | : 2011-09-20 |
| Genre | : Mathematics |
| ISBN | : 111815049X |
The most comprehensive, single-volume guide to conductingexperiments with mixtures "If one is involved, or heavily interested, in experiments onmixtures of ingredients, one must obtain this book. It is, as wasthe first edition, the definitive work." -Short Book Reviews (Publication of the International StatisticalInstitute) "The text contains many examples with worked solutions and with itsextensive coverage of the subject matter will prove invaluable tothose in the industrial and educational sectors whose work involvesthe design and analysis of mixture experiments." -Journal of the Royal Statistical Society "The author has done a great job in presenting the vitalinformation on experiments with mixtures in a lucid and readablestyle. . . . A very informative, interesting, and useful book on animportant statistical topic." -Zentralblatt fur Mathematik und Ihre Grenzgebiete Experiments with Mixtures shows researchers and students how todesign and set up mixture experiments, then analyze the data anddraw inferences from the results. Virtually every technique thathas appeared in the literature of mixtures can be found here, andcomputing formulas for each method are provided with completelyworked examples. Almost all of the numerical examples are takenfrom real experiments. Coverage begins with Scheffe latticedesigns, introducing the use of independent variables, and endswith the most current methods. New material includes: * Multiple response cases * Residuals and least-squares estimates * Categories of components: Mixtures of mixtures * Fixed as well as variable values for the major componentproportions * Leverage and the Hat Matrix * Fitting a slack-variable model * Estimating components of variances in a mixed model using ANOVAtable entries * Clarification of blocking mates and choice of mates * Optimizing several responses simultaneously * Biplots for multiple responses
| Author | : Clair L. Alston |
| Publisher | : John Wiley & Sons |
| Total Pages | : 411 |
| Release | : 2012-10-10 |
| Genre | : Mathematics |
| ISBN | : 1118394321 |
Provides an accessible foundation to Bayesian analysis using real world models This book aims to present an introduction to Bayesian modelling and computation, by considering real case studies drawn from diverse fields spanning ecology, health, genetics and finance. Each chapter comprises a description of the problem, the corresponding model, the computational method, results and inferences as well as the issues that arise in the implementation of these approaches. Case Studies in Bayesian Statistical Modelling and Analysis: Illustrates how to do Bayesian analysis in a clear and concise manner using real-world problems. Each chapter focuses on a real-world problem and describes the way in which the problem may be analysed using Bayesian methods. Features approaches that can be used in a wide area of application, such as, health, the environment, genetics, information science, medicine, biology, industry and remote sensing. Case Studies in Bayesian Statistical Modelling and Analysis is aimed at statisticians, researchers and practitioners who have some expertise in statistical modelling and analysis, and some understanding of the basics of Bayesian statistics, but little experience in its application. Graduate students of statistics and biostatistics will also find this book beneficial.
| Author | : Ronald Snee |
| Publisher | : SAS Institute |
| Total Pages | : 340 |
| Release | : 2016-09-27 |
| Genre | : Computers |
| ISBN | : 1629605301 |
Strategies for Formulations Development: A Step-by-Step Guide Using JMP is based on the authors' significant practical experience partnering with scientists to develop strategies to accelerate the formulation (mixtures) development process. The authors not only explain the most important methods used to design and analyze formulation experiments, but they also present overall strategies to enhance both the efficiency and effectiveness of the development process. With this book you will be able to: Approach the development process from a strategic viewpoint with the overall end result in mind. Design screening experiments to identify components that are most important to the performance of the formulation. Design optimization experiments to identify the maximum response in the design space. Analyze both screening and optimization experiments using graphical and numerical methods. Optimize multiple criteria, such as the quality, cost, and performance of product formulations. Design and analyze formulation studies that involve both formulation components and process variables using methods that reduce the required experimentation by up to 50%. Linking dynamic graphics with powerful statistics, JMP helps construct a visually compelling narrative to interactively share findings that are coherent and actionable by colleagues and decision makers. Using this book, you can take advantage of computer generated experiment designs when classical designs do not suffice, given the physical and economic constraints of the experiential environment. Strategies for Formulations Development: A Step-by-Step Guide Using JMP(R) is unique because it provides formulation scientists with the essential information they need in order to successfully conduct formulation studies in the chemical, biotech, and pharmaceutical industries.
| Author | : Dennis V. Lindley |
| Publisher | : John Wiley & Sons |
| Total Pages | : 434 |
| Release | : 2013-12-16 |
| Genre | : Mathematics |
| ISBN | : 1118650123 |
Praise for the First Edition "...a reference for everyone who is interested in knowing and handling uncertainty." —Journal of Applied Statistics The critically acclaimed First Edition of Understanding Uncertainty provided a study of uncertainty addressed to scholars in all fields, showing that uncertainty could be measured by probability, and that probability obeyed three basic rules that enabled uncertainty to be handled sensibly in everyday life. These ideas were extended to embrace the scientific method and to show how decisions, containing an uncertain element, could be rationally made. Featuring new material, the Revised Edition remains the go-to guide for uncertainty and decision making, providing further applications at an accessible level including: A critical study of transitivity, a basic concept in probability A discussion of how the failure of the financial sector to use the proper approach to uncertainty may have contributed to the recent recession A consideration of betting, showing that a bookmaker's odds are not expressions of probability Applications of the book’s thesis to statistics A demonstration that some techniques currently popular in statistics, like significance tests, may be unsound, even seriously misleading, because they violate the rules of probability Understanding Uncertainty, Revised Edition is ideal for students studying probability or statistics and for anyone interested in one of the most fascinating and vibrant fields of study in contemporary science and mathematics.
| Author | : John I. McCool |
| Publisher | : John Wiley & Sons |
| Total Pages | : 366 |
| Release | : 2012-08-06 |
| Genre | : Technology & Engineering |
| ISBN | : 1118351983 |
Understand and utilize the latest developments in Weibull inferential methods While the Weibull distribution is widely used in science and engineering, most engineers do not have the necessary statistical training to implement the methodology effectively. Using the Weibull Distribution: Reliability, Modeling, and Inference fills a gap in the current literature on the topic, introducing a self-contained presentation of the probabilistic basis for the methodology while providing powerful techniques for extracting information from data. The author explains the use of the Weibull distribution and its statistical and probabilistic basis, providing a wealth of material that is not available in the current literature. The book begins by outlining the fundamental probability and statistical concepts that serve as a foundation for subsequent topics of coverage, including: • Optimum burn-in, age and block replacement, warranties and renewal theory • Exact inference in Weibull regression • Goodness of fit testing and distinguishing the Weibull from the lognormal • Inference for the Three Parameter Weibull Throughout the book, a wealth of real-world examples showcases the discussed topics and each chapter concludes with a set of exercises, allowing readers to test their understanding of the presented material. In addition, a related website features the author's own software for implementing the discussed analyses along with a set of modules written in Mathcad®, and additional graphical interface software for performing simulations. With its numerous hands-on examples, exercises, and software applications, Using the Weibull Distribution is an excellent book for courses on quality control and reliability engineering at the upper-undergraduate and graduate levels. The book also serves as a valuable reference for engineers, scientists, and business analysts who gather and interpret data that follows the Weibull distribution
| Author | : Ruey S. Tsay |
| Publisher | : John Wiley & Sons |
| Total Pages | : 414 |
| Release | : 2013-11-11 |
| Genre | : Mathematics |
| ISBN | : 1118617754 |
An accessible guide to the multivariate time series tools used in numerous real-world applications Multivariate Time Series Analysis: With R and Financial Applications is the much anticipated sequel coming from one of the most influential and prominent experts on the topic of time series. Through a fundamental balance of theory and methodology, the book supplies readers with a comprehensible approach to financial econometric models and their applications to real-world empirical research. Differing from the traditional approach to multivariate time series, the book focuses on reader comprehension by emphasizing structural specification, which results in simplified parsimonious VAR MA modeling. Multivariate Time Series Analysis: With R and Financial Applications utilizes the freely available R software package to explore complex data and illustrate related computation and analyses. Featuring the techniques and methodology of multivariate linear time series, stationary VAR models, VAR MA time series and models, unitroot process, factor models, and factor-augmented VAR models, the book includes: • Over 300 examples and exercises to reinforce the presented content • User-friendly R subroutines and research presented throughout to demonstrate modern applications • Numerous datasets and subroutines to provide readers with a deeper understanding of the material Multivariate Time Series Analysis is an ideal textbook for graduate-level courses on time series and quantitative finance and upper-undergraduate level statistics courses in time series. The book is also an indispensable reference for researchers and practitioners in business, finance, and econometrics.
| Author | : David W. Hosmer, Jr. |
| Publisher | : John Wiley & Sons |
| Total Pages | : 528 |
| Release | : 2013-04-01 |
| Genre | : Mathematics |
| ISBN | : 0470582472 |
A new edition of the definitive guide to logistic regression modeling for health science and other applications This thoroughly expanded Third Edition provides an easily accessible introduction to the logistic regression (LR) model and highlights the power of this model by examining the relationship between a dichotomous outcome and a set of covariables. Applied Logistic Regression, Third Edition emphasizes applications in the health sciences and handpicks topics that best suit the use of modern statistical software. The book provides readers with state-of-the-art techniques for building, interpreting, and assessing the performance of LR models. New and updated features include: A chapter on the analysis of correlated outcome data A wealth of additional material for topics ranging from Bayesian methods to assessing model fit Rich data sets from real-world studies that demonstrate each method under discussion Detailed examples and interpretation of the presented results as well as exercises throughout Applied Logistic Regression, Third Edition is a must-have guide for professionals and researchers who need to model nominal or ordinal scaled outcome variables in public health, medicine, and the social sciences as well as a wide range of other fields and disciplines.
| Author | : Dhammika Amaratunga |
| Publisher | : John Wiley & Sons |
| Total Pages | : 320 |
| Release | : 2014-01-27 |
| Genre | : Mathematics |
| ISBN | : 111836452X |
Praise for the First Edition “...extremely well written...a comprehensive and up-to-date overview of this important field.” – Journal of Environmental Quality Exploration and Analysis of DNA Microarray and Other High-Dimensional Data, Second Edition provides comprehensive coverage of recent advancements in microarray data analysis. A cutting-edge guide, the Second Edition demonstrates various methodologies for analyzing data in biomedical research and offers an overview of the modern techniques used in microarray technology to study patterns of gene activity. The new edition answers the need for an efficient outline of all phases of this revolutionary analytical technique, from preprocessing to the analysis stage. Utilizing research and experience from highly-qualified authors in fields of data analysis, Exploration and Analysis of DNA Microarray and Other High-Dimensional Data, Second Edition features: A new chapter on the interpretation of findings that includes a discussion of signatures and material on gene set analysis, including network analysis New topics of coverage including ABC clustering, biclustering, partial least squares, penalized methods, ensemble methods, and enriched ensemble methods Updated exercises to deepen knowledge of the presented material and provide readers with resources for further study The book is an ideal reference for scientists in biomedical and genomics research fields who analyze DNA microarrays and protein array data, as well as statisticians and bioinformatics practitioners. Exploration and Analysis of DNA Microarray and Other High-Dimensional Data, Second Edition is also a useful text for graduate-level courses on statistics, computational biology, and bioinformatics.
| Author | : Shein-Chung Chow |
| Publisher | : John Wiley & Sons |
| Total Pages | : 838 |
| Release | : 2013-09-30 |
| Genre | : Mathematics |
| ISBN | : 1118458141 |
Praise for the Second Edition: “...a grand feast for biostatisticians. It stands ready to satisfy the appetite of any pharmaceutical scientist with a respectable statistical appetite.” —Journal of Clinical Research Best Practices The Third Edition of Design and Analysis of Clinical Trials provides complete, comprehensive, and expanded coverage of recent health treatments and interventions. Featuring a unified presentation, the book provides a well-balanced summary of current regulatory requirements and recently developed statistical methods as well as an overview of the various designs and analyses that are utilized at different stages of clinical research and development. Additional features of this Third Edition include: • New chapters on biomarker development and target clinical trials, adaptive design, trials for evaluating diagnostic devices, statistical methods for translational medicine, and traditional Chinese medicine • A balanced overview of current and emerging clinical issues as well as newly developed statistical methodologies • Practical examples of clinical trials that demonstrate everyday applicability, with illustrations and examples to explain key concepts • New sections on bridging studies and global trials, QT studies, multinational trials, comparative effectiveness trials, and the analysis of QT/QTc prolongation • A complete and balanced presentation of clinical and scientific issues, statistical concepts, and methodologies for bridging clinical and statistical disciplines • An update of each chapter that reflects changes in regulatory requirements for the drug review and approval process and recent developments in statistical design and methodology for clinical research and development Design and Analysis of Clinical Trials, Third Edition continues to be an ideal clinical research reference for academic, pharmaceutical, medical, and regulatory scientists/researchers, statisticians, and graduate-level students.
