A Historical Perspective On Evidence Based Immunology
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| Author | : Edward J. Moticka |
| Publisher | : Newnes |
| Total Pages | : 396 |
| Release | : 2015-11-25 |
| Genre | : Medical |
| ISBN | : 0123983754 |
A Historical Perspective on Evidence-Based Immunology focuses on the results of hypothesis-driven, controlled scientific experiments that have led to the current understanding of immunological principles. The text helps beginning students in biomedical disciplines understand the basis of immunologic knowledge, while also helping more advanced students gain further insights. The book serves as a crucial reference for researchers studying the evolution of ideas and scientific methods, including fundamental insights on immunologic tolerance, interactions of lymphocytes with antigen TCR and BCR, the generation of diversity and mechanism of tolerance of T cells and B cells, the first cytokines, the concept of autoimmunity, the identification of NK cells as a unique cell type, the structure of antibody molecules and identification of Fab and Fc regions, and dendritic cells. - Provides a complete review of the hypothesis-driven, controlled scientific experiments that have led to our current understanding of immunological principles - Explains the types of experiments that were performed and how the interpretation of the experiments altered the understanding of immunology - Presents concepts such as the division of lymphocytes into functionally different populations in their historical context - Includes fundamental insights on immunologic tolerance, interactions of lymphocytes with antigen TCR and BCR, and the generation of diversity and mechanism of tolerance of T and B cells
| Author | : Shailza Singh |
| Publisher | : Springer Nature |
| Total Pages | : 273 |
| Release | : 2020-04-24 |
| Genre | : Medical |
| ISBN | : 9811533504 |
Systems and Synthetic Immunology focuses on the similarities between biology and engineering at the systems level, which are important for applying engineering theories to biology problems. With the advent of new genomic techniques, there are numerous systematic investigations underway in the scientific world. This volume highlights techniques that can be used to effectively combine two of the most essential biological fields - Systems Biology and Synthetic Immunology. The respective chapters discuss the role of synthetic immunology in biotechnology, production of biomaterials, and their use in vaccine delivery. Further topics include the importance of cytokines; the use of genomic engineering tools in immunotherapy; immunosensors; nanotherapeutics; and bioinformatics tools in biomedical applications. Given its scope, the book offers readers an up-to-date and comprehensive review of this unique and dynamic field of research.
| Author | : Steven A. Frank |
| Publisher | : Princeton University Press |
| Total Pages | : 364 |
| Release | : 2002-07-21 |
| Genre | : Medical |
| ISBN | : 9780691095950 |
| Author | : Dale A. Stirling |
| Publisher | : CRC Press |
| Total Pages | : 589 |
| Release | : 2023-05-12 |
| Genre | : Medical |
| ISBN | : 1000574830 |
The COVID-19 pandemic provides stark evidence of the importance of medicine on a global scale. However, revisiting the influenza pandemic of 1918 provided a perspective as we searched for a viable vaccine and instituted public health measures. This shows that medical knowledge is an accumulative process extending to the past and it is in the spirit of that legacy that this bibliography has been compiled. The book is a one-stop resource that cites literature related to the historical aspects of medicine. It also acknowledges medicine’s global reach and devotes significant effort in that respect. Although the online world seems to dominate on both a social and educational level, there is still a need for thoughtfully curated and focused reference works and this bibliography accomplishes that goal. The book has 9,000+ citations. It utilizes the WHO's International classification of Diseases for the section on diseases and disorders and the U.S. Food & Drug Administration's Product Code Classification Database for the section on medical devices, equipment, and instruments. It includes detailed subject, geographuc, and people indexes for an easy reference.
| Author | : Shilpa Ravella |
| Publisher | : W. W. Norton & Company |
| Total Pages | : 215 |
| Release | : 2022-10-11 |
| Genre | : Medical |
| ISBN | : 0393541916 |
“Fascinating.…[Ravella’s writing] breathes life into biological functions.” —Grace Wade, New Scientist A riveting investigation of inflammation—the hidden force at the heart of modern disease—and how we can prevent, treat, or even reverse it. Inflammation is the body’s ancestral response to its greatest threats, the first line of defense it deploys against injury and foreign pathogens. But as the threats we face have evolved, new science is uncovering how inflammation may also turn against us, simmering underneath the surface of leading killers from heart disease and cancer to depression, aging, and mysterious autoimmune conditions. In A Silent Fire, gastroenterologist Shilpa Ravella investigates hidden inflammation’s emerging role as a common root of modern disease—and how we can control it. We meet the visionary nineteenth-century pathologist who laid the foundation for our modern understanding of inflammation, the eccentric Russian zoologist who discovered one of the cells central to our immune system, and the dedicated researchers advancing the frontiers of medical and nutritional science today. With fascinating case studies, Ravella reveals how we can reform our relationships with food and our microbiomes to benefit our own health and the planet’s. Synthesizing medical history, cutting-edge research, and innovative clinical practice, Ravella unveils inflammation as one potential basis for a unifying theory of disease. A paradigm-shifting understanding of one of the most mysterious, buzzed-about topics in medicine and nutrition, A Silent Fire shows us how to live not only long but well.
| Author | : Committee for the Study of the Future of Public Health |
| Publisher | : National Academies Press |
| Total Pages | : 240 |
| Release | : 1988-01-15 |
| Genre | : Medical |
| ISBN | : 0309581907 |
"The Nation has lost sight of its public health goals and has allowed the system of public health to fall into 'disarray'," from The Future of Public Health. This startling book contains proposals for ensuring that public health service programs are efficient and effective enough to deal not only with the topics of today, but also with those of tomorrow. In addition, the authors make recommendations for core functions in public health assessment, policy development, and service assurances, and identify the level of government--federal, state, and local--at which these functions would best be handled.
| Author | : Martin Flajnik |
| Publisher | : Lippincott Williams & Wilkins |
| Total Pages | : 3597 |
| Release | : 2022-07-19 |
| Genre | : Medical |
| ISBN | : 1975142527 |
Selected as a Doody's Core Title for 2022! Defining the field of immunology for 40 years, Paul’s Fundamental Immunology continues to provide detailed, authoritative, up-to-date information that uniquely bridges the gap between basic immunology and the disease process. The fully revised 8th edition maintains the excellence established by Dr. William E. Paul, who passed away in 2015, and is now under new editorial leadership of Drs. Martin F. Flajnik, Nevil J. Singh, and Steven M. Holland. It’s an ideal reference and gold standard text for graduate students, post-doctoral fellows, basic and clinical immunologists, microbiologists and infectious disease physicians, and any physician treating diseases in which immunologic mechanisms play a role.
| Author | : Indrakant Kumar Singh |
| Publisher | : CRC Press |
| Total Pages | : 377 |
| Release | : 2022-12-19 |
| Genre | : Science |
| ISBN | : 1000790991 |
Our immune system defends us against infection by employing multiple lines of defense. The relevance of the immune response in human health, disease prevention, and vaccinations becomes evident when the immune system is compromised as in the case of pathogenic infections or autoimmune diseases. The reader will gain a fundamental understanding of the essential principles of immunology, such as how our immune system recognizes/fights infectious agents, how our body differentiates between foreign and self-cells/molecules, and how the memory from previous infections aids in a faster and more effective immune response. The book is divided into 17 chapters, providing an overview of the immune system and its components, including its organs and cells. Chapters on the major histocompatibility complex, the complement system, hypersensitivity and tolerance, antibody diversity through DNA rearrangements, and autoimmune diseases are included in the book which further broadens the understanding of this very complex system of our body. Chapters on transplantation immunology and vaccines provide a perspective on the application of these immunological concepts and will be of great interest to readers. Key features of the book: Simple, direct, and lucid language Comprehensive coverage of concepts for better understanding Well-labeled illustrations, flowcharts, and tables for enhanced learning Every chapter is followed up with a detailed summary and questionnaire A detailed glossary for users to know the right words Chapters contributed/reviewed by experienced experts in this field The book provides broad, accessible, and up-to-date information about immunological perspectives to biotechnologists, biomedical scientists, biochemists, molecular biologists, and students from various streams of life sciences, including zoology, biotechnology, and microbiology, as well as instant access to a wealth of information.
| Author | : Bernd Kaspers |
| Publisher | : Academic Press |
| Total Pages | : 456 |
| Release | : 2012-12-02 |
| Genre | : Medical |
| ISBN | : 0123972728 |
The second edition of Avian Immunology provides an up-to-date overview of the current knowledge of avian immunology. From the ontogeny of the avian immune system to practical application in vaccinology, the book encompasses all aspects of innate and adaptive immunity in chickens. In addition, chapters are devoted to the immunology of other commercially important species such as turkeys and ducks, and to ecoimmunology summarizing the knowledge of immune responses in free-living birds often in relation to reproductive success. The book contains a detailed description of the avian innate immune system, encompassing the mucosal, enteric, respiratory and reproductive systems. The diseases and disorders it covers include immunodepressive diseases and immune evasion, autoimmune diseases, and tumors of the immune system. Practical aspects of vaccination are examined as well. Extensive appendices summarize resources for scientists including cell lines, inbred chicken lines, cytokines, chemokines, and monoclonal antibodies. The world-wide importance of poultry protein for the human diet, as well as the threat of avian influenza pandemics like H5N1 and heavy reliance on vaccination to protect commercial flocks makes this book a vital resource. This book provides crucial information not only for poultry health professionals and avian biologists, but also for comparative and veterinary immunologists, graduate students and veterinary students with an interest in avian immunology. - With contributions from 33 of the foremost international experts in the field, this book provides the most up-to-date review of avian immunology so far - Contains a detailed description of the avian innate immune system reviewing constitutive barriers, chemical and cellular responses; it includes a comprehensive review of avian Toll-like receptors - Contains a wide-ranging review of the "ecoimmunology" of free-living avian species, as applied to studies of population dynamics, and reviews methods and resources available for carrying out such research
| Author | : Matt Richtel |
| Publisher | : HarperCollins |
| Total Pages | : 446 |
| Release | : 2019-03-12 |
| Genre | : Science |
| ISBN | : 0062698508 |
National Bestseller "Gives you all the context you need to understand the science of immunity. ... An Elegant Defense left me with [a] sense of awe.” —Bill Gates, Gates Notes Summer Reading List The Pulitzer Prize–winning New York Times journalist "explicates for the lay reader the intricate biology of our immune system" (Jerome Groopman, MD, New York Review of Books) From New York Times science journalist Matt Richtel, An Elegant Defense is an acclaimed and definitive exploration of the immune system and the secrets of health. Interweaving cutting-edge science with the intimate stories of four individual patients, this epic, first-of-its-kind book “give[s] lay readers a means of understanding what’s known so far about the intricate biology of our immune systems” (The Week). The immune system is our body’s essential defense network, a guardian vigilantly fighting illness, healing wounds, maintaining order and balance, and keeping us alive. It has been honed by evolution over millennia to face an almost infinite array of threats. For all its astonishing complexity, however, the immune system can be easily compromised by fatigue, stress, toxins, advanced age, and poor nutrition—hallmarks of modern life—and even by excessive hygiene. Paradoxically, it is a fragile wonder weapon that can turn on our own bodies with startling results, leading today to epidemic levels of autoimmune disorders. An Elegant Defense effortlessly guides readers on a scientific detective tale winding from the Black Plague to twentieth-century breakthroughs in vaccination and antibiotics, to today’s laboratories that are revolutionizing immunology—perhaps the most extraordinary and consequential medical story of our time. Drawing on extensive new interviews with dozens of world-renowned scientists, Richtel has produced a landmark book, equally an investigation into the deepest riddles of survival and a profoundly human tale that is movingly brought to life through the eyes of his four main characters, each of whom illuminates an essential facet of our “elegant defense.”
