Wiley Encyclopedia of Chemical Biology, Volume 3

Wiley Encyclopedia of Chemical Biology, Volume 3
Author: Tadhg P. Begley
Publisher: Wiley-Blackwell
Total Pages: 836
Release: 2009-02-03
Genre: Science
ISBN:

The first major reference at the interface of chemistry, biology, and medicine Chemical biology is a rapidly developing field that uses the principles, tools, and language of chemistry to answer important questions in the life sciences. It has enabled researchers to gather critical information about the molecular biology of the cell and is the fundamental science of drug discovery, playing a key role in the development of novel agents for the prevention, diagnosis, and treatment of disease. Now students and researchers across the range of disciplines that use chemical biology techniques have a single resource that encapsulates what is known in the field. It is an excellent place to begin any chemical biology investigation. Major topics addressed in the encyclopedia include: Applications of chemical biology Biomolecules within the cell Chemical views of biology Chemistry of biological processes and systems Synthetic molecules as tools for chemical biology Technologies and techniques in chemical biology Some 300 articles range from pure basic research to areas that have immediate applications in fields such as drug discovery, sensor technology, and catalysis. Novices in the field can turn to articles that introduce them to the basics, whereas experienced researchers have access to articles exploring the cutting edge of the science. Each article ends with a list of references to facilitate further investigation. With contributions from leading researchers and pioneers in the field, the Wiley Encyclopedia of Chemical Biology builds on Wiley's unparalleled reputation for helping students and researchers understand the crucial role of chemistry and chemical techniques in the life sciences.

Natural Products in Chemical Biology

Natural Products in Chemical Biology
Author: Natanya Civjan
Publisher: John Wiley & Sons
Total Pages: 437
Release: 2012-07-03
Genre: Science
ISBN: 1118101170

Based on the award winning Wiley Encyclopedia of Chemical Biology, this book provides a general overview of the unique features of the small molecules referred to as "natural products", explores how this traditionally organic chemistry-based field was transformed by insights from genetics and biochemistry, and highlights some promising future directions. The book begins by introducing natural products from different origins, moves on to presenting and discussing biosynthesis of various classes of natural products, and then looks at natural products as models and the possibilities of using them in medicine.

Chemical Biology

Chemical Biology
Author: Natanya Civjan
Publisher: John Wiley & Sons
Total Pages: 657
Release: 2012-08-07
Genre: Science
ISBN: 1118434501

An authoritative look at the application of chemical biology in drug discovery and development Based on the award-winning Wiley Encyclopedia of Chemical Biology published in 2008, this book explores the role of chemical biology in drug discovery and development. The first part of the book reviews key principles and techniques used in the design and evaluation of drug candidates. The second part elucidates biological mechanisms of certain diseases, illuminating approaches to investigate and target these diseases. Comprising carefully selected reprints from the Encyclopedia as well as new contributions from leading scholars in the field, this book provides researchers in academia and industry with important information to aid in the development of novel agents to treat disease. Self-contained articles cover a variety of essential topics, including: The design, development, and optimization of drug candidates The pharmacokinetics and properties of drugs Drug transport and delivery Natural products and natural product models as pharmaceuticals Biological mechanisms underlying health and disease Treatment strategies for a range of diseases, from HIV to schizophrenia Chemical Biology is a top-notch guide and reference for anyone working in the areas of drug discovery and development, including researchers in chemical biology and other fields such as biochemistry, medicine, and pharmaceutical sciences.

Protein Purification

Protein Purification
Author: Jan-Christer Janson
Publisher: John Wiley & Sons
Total Pages: 712
Release: 1998
Genre: Medical
ISBN: 9780471186267

This is a state-of-the-art sourcebook on modern high-resolution biochemical separation techniques for proteins. It contains all the basic theory and principles used in protein chromatography and electrophoresis.

RNA Biology

RNA Biology
Author: Gunter Meister
Publisher: Wiley-VCH
Total Pages: 0
Release: 2011-05-16
Genre: Science
ISBN: 9783527322787

Written with biologists, biochemists and other molecular scientists in mind, this volume meets the long-felt need for a textbook dedicated to the topic and recreates the excitement surrounding the scientific revolution sparked by the discovery of RNA interference in 1998. Students and instructors alike will profit from the author's exclusive first-hand knowledge, drawing on his breakthrough discoveries at the Tuschl lab at Rockefeller University. Gunter Meister abandons the traditionalist treatment of nucleic acids found in most biochemistry and molecular biology texts, adopting instead a modern approach in both concept and scope. The text is divided into three parts, on mRNA, non-coding RNA, and RNomics, and the author addresses the traditional roles of RNA in the transmission and regulation of genetic information, as well as the recently discovered functions of small RNA species in pathogen defense, cell differentiation and higher-level genomic regulation. All set to become the standard for teaching molecular science to biologists and biochemists.

Nuclear Magnetic Resonance

Nuclear Magnetic Resonance
Author: Krystyna Kamienska-Trela
Publisher: Royal Society of Chemistry
Total Pages: 499
Release: 2012-03-12
Genre: Science
ISBN: 1849734852

As a spectroscopic method, nuclear magnetic resonance (NMR) has seen spectacular growth, both as a technique and in its applications. Today's applications of NMR span a wide range of scientific disciplines, from physics to biology to medicine. Each volume of Nuclear Magnetic Resonance comprises a combination of annual and biennial reports which together provide comprehensive coverage of the literature on this topic. This Specialist Periodical Report reflects the growing volume of published work involving NMR techniques and applications, in particular NMR of natural macromolecules, which is covered in two reports: NMR of Proteins and Nucleic Acids and NMR of Carbohydrates, Lipids and Membranes. In his foreword to the first volume, the then editor, Professor Robin Harris announced that the series would be a discussion on the phenomena of NMR and that articles will be critical surveys of the literature. This has certainly remained the case throughout the series, and in line with its predecessors, Volume 40 aims to provide a comprehensive coverage of the relevant NMR literature. For the current volume this relates to publications appearing between June 2009 and May 2010 (the nominal period of coverage in volume 1 was July 1970 to June 1971). Compared to the previous volume there are some new members of the reporting team. Theoretical Aspects of Spin-Spin Couplings are covered by J. Jazwinski, while E. Swiezewska and J.Wojcik provide an account of NMR of Carbohydrates, Lipids and Membranes.

NMR Crystallography

NMR Crystallography
Author: Robin K. Harris
Publisher: John Wiley & Sons
Total Pages: 523
Release: 2009-12-21
Genre: Science
ISBN: 0470699612

The content of this volume has been added to eMagRes (formerly Encyclopedia of Magnetic Resonance) - the ultimate online resource for NMR and MRI. The term "NMR Crystallography" has only recently come into common usage, and even now causes raised eyebrows within some parts of the diffraction community. The power of solid-state NMR to give crystallographic information has considerably increased since the CPMAS suite of techniques was introduced in 1976. In the first years of the 21st century, the ability of NMR to provide information to support and facilitate the analysis of single-crystal and powder diffraction patterns has become widely accepted. Indeed, NMR can now be used to refine diffraction results and, in favorable cases, to solve crystal structures with minimal (or even no) diffraction data. The increasing ability to relate chemical shifts (including the tensor components) to the crystallographic location of relevant atoms in the unit cell via computational methods has added significantly to the practice of NMR crystallography. Diffraction experts will increasingly welcome NMR as an allied technique in their structural analyses. Indeed, it may be that in the future crystal structures will be determined by simultaneously fitting diffraction patterns and NMR spectra. This Handbook is organised into six sections. The first contains an overview and some articles on fundamental NMR topics, followed by a section concentrating on chemical shifts, and one on coupling interactions. The fourth section contains articles describing how NMR results relate to fundamental crystallography concepts and to diffraction methods. The fifth section concerns specific aspects of structure, such as hydrogen bonding. Finally, four articles in the sixth section give applications of NMR crystallography to structural biology, organic & pharmaceutical chemistry, inorganic & materials chemistry, and geochemistry. About EMR Handbooks / eMagRes Handbooks The Encyclopedia of Magnetic Resonance (up to 2012) and eMagRes (from 2013 onward) publish a wide range of online articles on all aspects of magnetic resonance in physics, chemistry, biology and medicine. The existence of this large number of articles, written by experts in various fields, is enabling the publication of a series of EMR Handbooks / eMagRes Handbooks on specific areas of NMR and MRI. The chapters of each of these handbooks will comprise a carefully chosen selection of articles from eMagRes. In consultation with the eMagRes Editorial Board, the EMR Handbooks / eMagRes Handbooks are coherently planned in advance by specially-selected Editors, and new articles are written (together with updates of some already existing articles) to give appropriate complete coverage. The handbooks are intended to be of value and interest to research students, postdoctoral fellows and other researchers learning about the scientific area in question and undertaking relevant experiments, whether in academia or industry. Have the content of this Handbook and the complete content of eMagRes at your fingertips! Visit: www.wileyonlinelibrary.com/ref/eMagRes View other eMagRes publications here

Advances in Chemical Biology – An Approach In Future Perspectives Volume – 3

Advances in Chemical Biology – An Approach In Future Perspectives Volume – 3
Author: Dr. Nandeshwarappa B. P. M. Sc., Ph.D.
Publisher: Shineeks Publishers
Total Pages: 190
Release: 2023-06-21
Genre: Education
ISBN:

Advances in Chemical Biology – Volume 3 The current book summary envisages the basic aspects of chemistry and biology thoughts, with the allied area of multidiscipline which comprises applications of chemical and biological disciplines and these are significant literatureto innovative minds to enrich their knowledge by research topics as anilluminative element to focus it in their research studies in the field of sciences. The book highlights research objectives on synthetic chemistry, newer approach of synthesis process and their various applications in in vitro and in vivo level as per the pharmaceutical industry requirements for commercialize the product to cure the various diseases and ailments for science and society. Recent innovations are highly applied and as per the demand of pharma sector and these are new perspectives to troubleshoot the newer problems with the help of molecular approach and bioinformatics applications.Understanding by the assimilation of basic to applied core research concepts in chemistry and their allied branches brings many applications, using novel methodologies, classic principles, defined protocols, emerging technologies by knowing similar issues and their impact in current-day problems in the science field. Hence, it’s multidisciplinary research to emphasize novel synthetic molecules which exhibit to safer, cheaper, and ecological drug for futuremedicine. The applications aimed on humans and animals as an important therapeutic drug for pharma industry. It is highly comprehensive book volume summarising various features of An Approach to Future Perspectives for academic research and industrial research in advanced level for all the learners in the area of chemistry and biology. It would be the best literature for the researchers and it can be a key reference book for the findings of new research problems to work for new drug discovery. This book has been peer-reviewed and free from plagiarism; hence it is highly useful for science and technology. It’s our great pleasure to wish all the readers, researchers, and industrialists to utilize it to accomplish new milestones as an innovation and novel discovery for future perspectives.

Chemical Biology of Natural Products

Chemical Biology of Natural Products
Author: David J. Newman
Publisher: CRC Press
Total Pages: 650
Release: 2017-09-22
Genre: Medical
ISBN: 1351643282

Chemical Biology of Natural Products This unique, long-awaited volume is designed to address contemporary aspects of natural product chemistry and its influence on biological systems, not solely on human interactions. The subjects covered include discovery, isolation and characterization, biosynthesis, biosynthetic engineering, pharmaceutical, and other applications of these compounds. Each chapter begins with a brief and simple introduction to the subject matter, and then proceeds to guide the reader towards the more contemporary, cutting-edge research in the field, with the contributing authors presenting current examples from their own work in order to exemplify key themes. Topics covered in the text include genome mining, heterologous expression, natural product synthesis, biosynthesis, glycosylation, chemical ecology, and therapeutic applications of natural products, both current and potential.

Catalysis from A to Z

Catalysis from A to Z
Author: Boy Cornils
Publisher: John Wiley & Sons
Total Pages: 0
Release: 2013-05-06
Genre: Science
ISBN: 9783527333073

The updated fourth edition of this successful encyclopedia contains 40% more high-quality content from over 300 international experts in four volumes! Comprehensive, succinct, and unrivaled, it includes all the knowledge scientists need on homogeneous, heterogeneous and biochemical catalysis in easy-to-use, compact entries for over 11,000 keywords in alphabetical order. In this way it explains briefly the important terms for every aspect of catalysis, whether biocatalysis, homogeneous catalysis, heterogeneous catalysis, or such related topics as spectroscopy or analytical methods. These also include abbreviations, brief biographic entries of important scientists who have worked in catalysis, trade names, important catalytic processes, named reactions, and other important keywords in the general field of catalysis. To round this work off, many of the keywords are illustrated and include German and French equivalent terms.