This volume contains the proceedings of the AMS Special Session on Representations of Lie Algebras, Quantum Groups and Related Topics, held from November 12–13, 2016, at North Carolina State University, Raleigh, North Carolina. The articles cover various aspects of representations of Kac–Moody Lie algebras and their applications, structure of Leibniz algebras and Krichever–Novikov algebras, representations of quantum groups, and related topics.