Studies

Studies
Author: Rockefeller Institute for Medical Research
Publisher:
Total Pages: 738
Release: 1914
Genre: Medicine
ISBN:

Verhandlungen

Verhandlungen
Author: Deutsche Gesellschaft für Verdauungs- und Stoffwechselkrankheiten
Publisher:
Total Pages: 910
Release: 1958
Genre: Digestive organs
ISBN:

Crossing the Boundaries of Life

Crossing the Boundaries of Life
Author: Karl S. Matlin
Publisher: University of Chicago Press
Total Pages: 367
Release: 2022-05-10
Genre: Science
ISBN: 0226819353

A close look at Günter Blobel’s transformative contributions to molecular cell biology. The difficulty of reconciling chemical mechanisms with the functions of whole living systems has plagued biologists since the development of cell theory in the nineteenth century. As Karl S. Matlin argues in Crossing the Boundaries of Life, it is no coincidence that this longstanding knot of scientific inquiry was loosened most meaningfully by the work of a cell biologist, the Nobel laureate Günter Blobel. In 1975, using an experimental setup that did not contain any cells at all, Blobel was able to target newly made proteins to cell membrane vesicles, enabling him to theorize how proteins in the cell distribute spatially, an idea he called the signal hypothesis. Over the next twenty years, Blobel and other scientists were able to dissect this mechanism into its precise molecular details. For elaborating his signal concept into a process he termed membrane topogenesis—the idea that each protein in the cell is synthesized with an "address" that directs the protein to its correct destination within the cell—Blobel was awarded the Nobel Prize in Physiology or Medicine in 1999. Matlin argues that Blobel’s investigative strategy and its subsequent application addressed a fundamental unresolved dilemma that had bedeviled biology from its very beginning—the relationship between structure and function—allowing biology to achieve mechanistic molecular explanations of biological phenomena. Crossing the Boundaries of Life thus uses Blobel’s research and life story to shed light on the importance of cell biology for twentieth-century science, illustrating how it propelled the development of adjacent disciplines like biochemistry and molecular biology.

Elsevier's Dictionary of Geography

Elsevier's Dictionary of Geography
Author: Vladimir Kotlyakov
Publisher: Elsevier
Total Pages: 1073
Release: 2006-12-20
Genre: Science
ISBN: 0080488781

Geography is a system of highly developed sciences about the environment. Geographical science embracing the study of the Earth's physical phenomena, people and their economic activities has always been in need of an extensive terminology. Geographical terms are related to the terms of natural sciences (physics, chemistry, biology, geology, etc.) and humanities (history, economics, sociology, etc.) since geography is based on these fundamental subjects. Geography includes a number of disciplines and subdivisions which appeared along with the development of the science In spite of being very different geographical disciplines have some common tools of investigation which is maps, comparative method of exploration, remote sensing, geoinformation systems. Today very well developed terminologies of all the specialist fields of geography and related subjects exist in the main world languages. However, they are not always well-correlated. Nowadays geographical terminology requires unification and international correlation more than ever before. Hence the idea of compiling a multilingual polydisciplinary dictionary. The Dictionary consists of the basic table of terms arranged according to the order of the English alphabet with each term numbered. Each entry consists of the term in English and its equivalents in Russian, French, German, Spanish. Short definitions of terms are given in English and in Russian. The terms are supplied with the necessary grammar labels, such as gender of nouns, plural number, etc. The Dictionary combines two functions: that of a defining dictionary and that of a bilingual dictionary. These two functions are basically contradictory because usually the defining dictionary is aimed at giving one meaning of the word which is the main and essential one, while the bilingual dictionary tries to give different equivalents of a given word in the other language in order to supply the user with maximum possible translations, differing in the shades of meanings, thus giving him the possibility to choose the appropriate word. But in our Dictionary we intentionally decided to combine the two functions – defining and multilingual, because a short definition of the term and equivalents in other languages help to achieve our main aim which consists in showing the basic geographical terminology and harmonizing it in several languages. Having this into consideration we deliberately mixed two types of dictionaries in one. - Organized alphabetically via English - Provides short definition of geographical terms in English and Russian - Includes multilingual translation of terms from English to Russian, French, German, Spanish

Journal Du Conseil

Journal Du Conseil
Author: International Council for the Exploration of the Sea
Publisher:
Total Pages: 418
Release: 1927
Genre: Fisheries
ISBN: