Vitamin D in Chronic Kidney Disease

Vitamin D in Chronic Kidney Disease
Author: Pablo A. Ureña Torres
Publisher: Springer
Total Pages: 583
Release: 2016-09-21
Genre: Medical
ISBN: 3319325078

Vitamin D deficiency, circulating levels lower than 15 ng/ml, is an epidemic disease worldwide with more than a billion people suffering of it in the beginning of the 21-century. Besides its impact on mineral and bone metabolism, these low vitamin D levels are also associated with a diversity of non-skeletal complications, among them cardiovascular disease, diabetes mellitus, multiple sclerosis, cancer, tuberculosis, and immune system dysfunction. Chronic Kidney Disease is also a very common disease, affecting more than 10% of the world population, ranging from stage 1 to stage 5 before dialysis. Approximately 1% of the population in industrialized countries is affected by end-stage renal disease (ESRD), needing a renal replacement therapy either hemodialysis or peritoneal dialysis, and ultimately by renal transplantation. Those CKD patients are more susceptible to exhibit reduced vitamin D stocks. Consequently, more than eighty percent of CKD patients have either insufficient or deficient vitamin D levels for multiple reasons.

Chronic Kidney Disease

Chronic Kidney Disease
Author: Junwei Yang
Publisher: Springer Nature
Total Pages: 253
Release: 2019-11-08
Genre: Medical
ISBN: 9813291311

This book provides a comprehensive and systematic review of the latest findings in a wide spectrum of clinically important aspects of chronic kidney disease (CKD), focusing on clinical diagnosis and therapeutics. CKD is a global health problem with a rising morbidity and mortality. The last decade has seen significant improvements in determining the incidence, prevalence, and complications of CKD, mainly thanks to the definitions of CKD developed by the National Kidney Foundation’s Kidney Disease Outcomes Quality Initiative (K/DOQI). However, increased recognition of CKD has led to awareness of the limitations of its clinical diagnosis and treatment, which are essential to patients’ wellbeing. This book is of particular value not only to nephrologists, but also to general practitioners and residents with an interest in CKD. It offers a well-organized exposition of the current knowledge base. Compared with previously published books on kidney disease and CKD, it has a smaller number of more concise chapters. As a result, readers can easily obtain an overview of the most important topics in CKD. We hope that practitioners will gain as much from reading this practical guide to clinical management of CKD as we have from editing it.

Itch

Itch
Author: E. Carstens
Publisher: CRC Press
Total Pages: 482
Release: 2014-02-25
Genre: Science
ISBN: 1466505435

Advances in itch research have elucidated differences between itch and pain but have also blurred the distinction between them. There is a long debate about how somatic sensations including touch, pain, itch, and temperature sensitivity are encoded by the nervous system. Research suggests that each sensory modality is processed along a fixed, direct-line communication system from the skin to the brain. Itch: Mechanisms and Treatment presents a timely update on all aspects of itch research and the clinical treatment of itch that accompanies many dermatological conditions including psoriasis, neuropathic itch, cutaneous t-cells lymphomas, and systemic diseases such as kidney and liver disease and cancer. Composed of contributions from distinguished researchers around the world, the book explores topics such as: Neuropathic itch Peripheral neuronal mechanism of itch The role of PAR-2 in neuroimmune communication and itch Mrgprs as itch receptors The role of interleukin-31 and oncostatin M in itch and neuroimmune communication Spinal coding of itch and pain Spinal microcircuits and the regulation of itch Examining new findings on cellular and molecular mechanisms, the book is a compendium of the most current research on itch, its prevalence in society, and the problems associated with treatment.

Phosphate and Vitamin D in Chronic Kidney Disease

Phosphate and Vitamin D in Chronic Kidney Disease
Author: M.S. Razzaque
Publisher: Karger Medical and Scientific Publishers
Total Pages: 164
Release: 2013-05-02
Genre: Medical
ISBN: 3318023698

The enormous progress made during the last decade has resulted in a better conceptual understanding of mineral ion metabolism in general. With regard to chronic kidney disease, the two most affected nutrients are phosphate and vitamin D. This book provides an overview of the physiological aspects of phosphate and vitamin D metabolism, and how their pathological dysregulation facilitates advancement of chronic kidney disease. It looks into the complex molecular and organ cross-talks during disease progression that range from the involvement of fibroblast growth factor (FGF23)-klotho system to impaired phosphate transport to hormonal dysfunctions of PTH and vitamin D. Each chapter clearly presents the clinically and biologically important problems and lists the key unsolved issues related to chronic kidney disease and beyond. Illustrations explaining multi-factorial and multi-organ interactions provide an easy outline for the reader to appreciate the complex biological pathways. For those without prior familiarity with the subject matter, this volume may serve as a quick reference to get updated information on phosphate and vitamin D metabolism.

Uremic Toxins

Uremic Toxins
Author: Severin Ringoir
Publisher: Springer Science & Business Media
Total Pages: 292
Release: 2012-12-06
Genre: Science
ISBN: 1468454455

The present book contains the Proceedings of a two day Symposium on Uremic Toxins organized at the University of Ghent in Belgium. A series of guest lectures, free communications and posters have been presented. An international audience of 163 scientists from 16 nationalities listened to and discussed extensively a spectrum of topics brought forward by colleagues and researchers who worked for many years in the field of Uremic Toxins. There is a striking contrast between all the new dialysis strategies available in the work to "clean" the uremic patients and the almost non-progression of our knowledge on uremic toxins in the past decade. In this sense the symposium was felt by all participants as a new start for the research in the biochemical field of the definition of uremia. If the present volume would stimulate new work in this field in order to define uremia, or identify the uremic toxins, the purpose of the organizers would be maximally fulfilled.

Endocrine Disorders in Kidney Disease

Endocrine Disorders in Kidney Disease
Author: Connie M. Rhee
Publisher: Springer
Total Pages: 346
Release: 2019-03-13
Genre: Medical
ISBN: 3319977652

This comprehensive book examines the complex interplay between endocrine and kidney disorders, and how this inter-relationship impacts patients with chronic kidney disease. Authored by experts in areas of endocrinology and nephrology, chapters cover a variety of topics, including diabetes, metabolic syndrome, thyroid dysfunction, gonadal disorders, dyslipidemia, mineral bone disorders, obesity, and pituitary disorders. These comorbidities are thoroughly examined and provide the clinician, researcher, and trainee with a greater understanding of the impact of endocrine disorders on kidney disease patients, the ability to identify persistent gaps in knowledge for future investigation, and move closer towards the goal of improving the health and survival of the chronic kidney disease population.

Parathyroid Glands in Chronic Kidney Disease

Parathyroid Glands in Chronic Kidney Disease
Author: Adrian Covic
Publisher: Springer Nature
Total Pages: 194
Release: 2020-05-07
Genre: Medical
ISBN: 3030437698

This concise book provides practical strategies to help nephrologists and endocrinologists correctly diagnose and treat the various forms of parathyroid disease they may encounter in the management of chronic kidney disease. Each chapter deals with various topics related to parathyroid gland anatomy and physiology, as well as diagnostic tests and their particularities in regard to chronic disease. The book highlights the range of therapies used for the treatment of secondary hyperparathyroidism, and critically analyses the latest research in the field. Providing an up-to-date review of the current literature, including innovations in both medical and surgical treatment and current indications for parathyroidectomy, this practice-oriented book is an excellent resource for nephrologists, endocrinologists, endocrine surgeons and family medicine physicians.

Coping with Kidney Disease

Coping with Kidney Disease
Author: Mackenzie Walser
Publisher: John Wiley & Sons
Total Pages: 247
Release: 2010-12-22
Genre: Medical
ISBN: 1118039777

A revolutionary program that can indefinitely postpone the need for dialysis If you've been diagnosed with kidney failure, this book could save your life. If you suffer from diabetes, hypertension, obesity, or any of a host of conditions that put you at risk for kidney disease, you owe it to yourself to read what is in this book. If you are among the 60,000 North Americans who go on dialysis each year, the information in this book could substantially improve your quality of life. In Coping with Kidney Disease, a leading expert tells you, in plain English, what you need to know to: * Understand kidney failure * Recognize early warning signs of kidney failure * Get a proper diagnosis * Talk with your doctors about it * Confidently evaluate treatment options * Take charge of your treatment * Delay dialysis or even avoid the need for it altogether The centerpiece of Coping with Kidney Disease is Dr. Walser's revolutionary 12-step program for avoiding dialysis. Based on treatments he has pioneered with his own patients at the Johns Hopkins University School of Medicine, the program calls for a supplemented low-protein diet supported by treatments to control blood pressure and correct high cholesterol. So effective has this breakthrough strategy proven to be that in many patients it actually worked to slow or arrest the progression of kidney failure to the end stage. Knowledge is power. Coping with Kidney Disease empowers you with what you need to take charge of kidney disease.

Nutrition in Kidney Disease

Nutrition in Kidney Disease
Author: Laura D. Byham-Gray
Publisher: Springer Science & Business Media
Total Pages: 495
Release: 2014-01-23
Genre: Medical
ISBN: 1627036857

Nutrition in Kidney Disease, Second Edition addresses the relationships between nutrition and (1) normal kidney function and disease, (2) the progressiveness of chronic kidney disease (CKD) and strategies to prevent further compromise, and (3) the treatment and management of kidney failure especially during medical crises, such as acute kidney injury and its consequent nutritional therapies (e.g., enteral and parenteral nutrition). Demographic patterns, trends and outcomes in the current health care systems are explored in the United States and abroad. Disease prevention and management are presented over the entire lifespan, beginning with pregnancy, followed by infancy, childhood, adolescence, and adulthood, concluding with the elder years. Foundations for clinical practice are established by devoting a complete section towards conducting a comprehensive nutritional assessment, comprising of anthropometric, biochemical, clinical, physical parameters and psychosocial concerns unique to the kidney disease population. Nutritional therapy is also discussed across the spectrum of kidney disease, and pertinent aspects critical to successful management of disorders and conditions, such as bone disease, obesity, and nephrotic syndrome are explored. Nutrition in Kidney Disease, Second edition highlights cutting edge research in regards to exercise and functional outcomes, malnutrition and the inflammatory response, experimental therapies, and the use of complementary and alternative medicine, with a special emphasis on relevant preventative strategies.

Handbook of Vitamin D in Human Health

Handbook of Vitamin D in Human Health
Author: Ronald Ross Watson
Publisher: Brill Wageningen Academic
Total Pages: 0
Release: 2013
Genre: Medical
ISBN: 9789086862108

The authors document and define many of the key health related roles of vitamin D. Its traditional application in bone and muscle health as well as therapy of arthritis is expanded and clarified with new research. A better understanding of the effects of vitamin D inadequacy is modelled using problems ranging from infant growth retardation to chronic kidney and periodontal disease. Uniquely the vitamin's role in resistance and treatment of infectious diseases is shown in examples ranging from HIV/AIDS to tuberculosis. Mechanistic understanding of vitamin D's actions is enhanced by looking into its effects on immune modulation and inflammation. Expansion of the role of sunlight in stimulating vitamin D production is discussed relative to the reduction in a variety of cancers.