The purpose of this investigation was to determine the vapor-liquid equilibria of the binary system consisting of bromine pentafluoride and uranium hexafluoride. Data on vapor-liquid equilibria have both a fundamental and applied significances. From the standpoint of physical chemistry, the data give insight into molecular interactions in the solution as evidenced by the degree of non-ideal behavior. From the chemical engineering point of view, the data give rise to the x-y curves which form the basis for determining the number of theoretical plates or transfer units in the design of a distillation column to separate the components.