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| Author | : Tara Haelle |
| Publisher | : Twenty-First Century Books (Tm) |
| Total Pages | : 124 |
| Release | : 2018 |
| Genre | : Juvenile Nonfiction |
| ISBN | : 1512425303 |
"Learn more about the history and success rate of vaccines as well as their limitations, explore the challenges the medical community faces, and discover what vaccines are currently in development."--Provided by publisher.
| Author | : Institute of Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 382 |
| Release | : 1991-01-01 |
| Genre | : Medical |
| ISBN | : 0309044995 |
Parents have come to depend on vaccines to protect their children from a variety of diseases. Some evidence suggests, however, that vaccination against pertussis (whooping cough) and rubella (German measles) is, in a small number of cases, associated with increased risk of serious illness. This book examines the controversy over the evidence and offers a comprehensively documented assessment of the risk of illness following immunization with vaccines against pertussis and rubella. Based on extensive review of the evidence from epidemiologic studies, case histories, studies in animals, and other sources of information, the book examines: The relation of pertussis vaccines to a number of serious adverse events, including encephalopathy and other central nervous system disorders, sudden infant death syndrome, autism, Guillain-Barre syndrome, learning disabilities, and Reye syndrome. The relation of rubella vaccines to arthritis, various neuropathies, and thrombocytopenic purpura. The volume, which includes a description of the committee's methods for evaluating evidence and directions for future research, will be important reading for public health officials, pediatricians, researchers, and concerned parents.
| Author | : Institute of Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 237 |
| Release | : 2013-04-27 |
| Genre | : Medical |
| ISBN | : 0309267021 |
Vaccines are among the most safe and effective public health interventions to prevent serious disease and death. Because of the success of vaccines, most Americans today have no firsthand experience with such devastating illnesses as polio or diphtheria. Health care providers who vaccinate young children follow a schedule prepared by the U.S. Advisory Committee on Immunization Practices. Under the current schedule, children younger than six may receive as many as 24 immunizations by their second birthday. New vaccines undergo rigorous testing prior to receiving FDA approval; however, like all medicines and medical interventions, vaccines carry some risk. Driven largely by concerns about potential side effects, there has been a shift in some parents' attitudes toward the child immunization schedule. The Childhood Immunization Schedule and Safety identifies research approaches, methodologies, and study designs that could address questions about the safety of the current schedule. This report is the most comprehensive examination of the immunization schedule to date. The IOM authoring committee uncovered no evidence of major safety concerns associated with adherence to the childhood immunization schedule. Should signals arise that there may be need for investigation, however, the report offers a framework for conducting safety research using existing or new data collection systems.
| Author | : Institute of Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 304 |
| Release | : 2002-07-02 |
| Genre | : Medical |
| ISBN | : 0309169887 |
By two years of age, healthy infants in the United States can receive up to 20 vaccinations to protect against 11 diseases. Although most people know that vaccines effectively protect against serious infectious diseases, approximately one-quarter of parents in a recent survey believe that infants get more vaccines than are good for them, and that too many immunizations could overwhelm an infant's immune system. The Immunization Safety Review Committee reviewed the evidence regarding the hypothesis that multiple immunizations increase the risk for immune dysfunction. Specifically, the committee looked at evidence of potential biological mechanisms and at epidemiological evidence for or against causality related to risk for infections, the autoimmune disease type 1 diabetes, and allergic disorders.
| Author | : Tara Haelle |
| Publisher | : Twenty-First Century Books ™ |
| Total Pages | : 121 |
| Release | : 2018-01-01 |
| Genre | : Young Adult Nonfiction |
| ISBN | : 1541522087 |
Vaccines are biological substances that cause the human immune system to build up its defenses against specific diseases. Public health officials recommend a series of vaccines for all children, as well as some vaccines for teenagers and adults. But not everyone gets the vaccines they need. Many poor nations don't have the resources to deliver vaccines to every community. Some parents refuse to have their children vaccinated because they don't believe the evidence proving that vaccines are safe. The effort to wipe out diseases using vaccines continues. Vaccine Investigation recounts the fascinating history of vaccines, their important role in protecting community health, and the excitement of cutting-edge research.
| Author | : Institute of Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 153 |
| Release | : 2005-05-29 |
| Genre | : Medical |
| ISBN | : 0309095913 |
The Vaccine Safety Datalink (VSD) is a large, linked database of patient information that was developed jointly by CDC and several private managed care organizations in 1991. It includes data on vaccination histories, health outcomes, and characteristics of more than 7 million patients of eight participating health organizations. Researchers from CDC and the managed care groups have used VSD information to study whether health problems are associated with vaccinations. The subsequent VSD data sharing program was launched in 2002 to allow independent, external researchers access to information in the database. In this report, the committee that was asked to review aspects of this program recommends that two new oversight groups are needed to ensure that the policies and procedures of the VSD and its data sharing program are implemented as fairly and openly as possible.
| Author | : Susan Hahné |
| Publisher | : Routledge |
| Total Pages | : 471 |
| Release | : 2021-09-13 |
| Genre | : Medical |
| ISBN | : 1351679910 |
Vaccination programmes are of vital importance to public health and are present in virtually every country in the world. By promoting an understanding of the diverse effects of vaccination programmes, this textbook discusses how epidemiologic methods can be used to study, in real life, their impacts, benefits and risks. Written by expert practitioners in an accessible and concise style, this book is interspersed with practical examples which allow readers to acquire understanding through real-life data and problems. Part I provides an overview of basic concepts in vaccinology, immunology, vaccination programmes, infectious disease transmission dynamics, the various impacts of vaccination programmes and their societal context. Part II covers the main field tools used for the epidemiological evaluation of vaccination programmes: monitoring coverage and attitudes towards vaccination, surveillance of vaccine-preventable diseases and pathogens, seroepidemiological studies, methods to assess impact and outbreak investigation. Part III is dedicated to vaccine effectiveness and its assessment. Part IV includes an overview of the potential risks of vaccination and how to study these. Lastly, Part V deals with methods for an integrated assessment of benefits and risks of vaccination programmes. Suitable for professionals working in public health, epidemiology, biology and those working in health economics and vaccine development, Vaccination Programmes also serves as a textbook for postgraduate students in public health, epidemiology and infectious diseases. The book is aimed at all those involved in the many aspects of vaccination programmes, including public health professionals and epidemiologists. Its primary target audiences are master and doctoral students in infectious disease epidemiology and public health, post-doctoral participants of field epidemiology training programmes and public health professionals working in the post-implementation epidemiological evaluation of vaccines and vaccination programmes. The Open Access version of this book, available at http://www.taylorfrancis.com, has been made available under a Creative Commons Attribution-Non Commercial-No Derivatives (CC-BY-NC-ND) 4.0 license
| Author | : Institute of Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 71 |
| Release | : 1997-08-10 |
| Genre | : Medical |
| ISBN | : 0309057914 |
On November 6, 1995, the Institute of Medicine's Vaccine Safety Forum convened a workshop on detecting and responding to adverse events following vaccination. Workshop speakers and participants discussed the difficulties in detecting adverse events, current adverse events detection and response methods and procedures, suggestions for improving the means of detecting and responding to adverse events following vaccination, and future areas of research. This document represents a summary of that workshop.
| Author | : Institute of Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 118 |
| Release | : 2003-12-26 |
| Genre | : Medical |
| ISBN | : 0309086108 |
The Immunization Safety Review Committee was established by the Institute of Medicine (IOM) to evaluate the evidence on possible causal associations between immunizations and certain adverse outcomes, and to then present conclusions and recommendations. The committee's mandate also includes assessing the broader societal significance of these immunization safety issues. While all the committee members share the view that immunization is generally beneficial, none of them has a vested interest in the specific immunization safety issues that come before the group. The committee reviews three immunization safety review topics each year, addressing each one at a time. In this fifth report in a series, the committee examines the hypothesis that exposure to polio vaccine contaminated with simian virus 40 (SV40), a virus that causes inapparent infection in some monkeys, can cause certain types of cancer.
| Author | : Institute of Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 481 |
| Release | : 1993-01-01 |
| Genre | : Medical |
| ISBN | : 0309048958 |
Childhood immunization is one of the major public health measures of the 20th century and is now receiving special attention from the Clinton administration. At the same time, some parents and health professionals are questioning the safety of vaccines because of the occurrence of rare adverse events after immunization. This volume provides the most thorough literature review available about links between common childhood vaccinesâ€"tetanus, diphtheria, measles, mumps, polio, Haemophilus influenzae b, and hepatitis Bâ€"and specific types of disorders or death. The authors discuss approaches to evidence and causality and examine the consequencesâ€"neurologic and immunologic disorders and deathâ€"linked with immunization. Discussion also includes background information on the development of the vaccines and details about the case reports, clinical trials, and other evidence associating each vaccine with specific disorders. This comprehensive volume will be an important resource to anyone concerned about the immunization controversy: public health officials, pediatricians, attorneys, researchers, and parents.
