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| Author | : |
| Publisher | : Academic Press |
| Total Pages | : 269 |
| Release | : 2011-09-16 |
| Genre | : Science |
| ISBN | : 0123876982 |
This latest volume in Advances in Genetics covers the genetics of Circadian rhythms. With an international group of authors this volume is the latest offering in this widely praised series.
| Author | : Pierpaolo Degano |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 337 |
| Release | : 2009-08-17 |
| Genre | : Computers |
| ISBN | : 3642038441 |
This book constitutes the refereed proceedings of the 7th International Conference on Computational Methods in Systems Biology, CMSB 2009, held in Bologna, Italy, August 31 - September 1, 2009. The 18 revised full papers presented together with the summaries of 3 invited papers were carefully reviewed and selected from more than 45 submissions. The papers cover theoretical or applied contributions that are motivated by a biological question focusing on modeling approaches, including process algebra, simulation approaches, analysis methods, in particular model checking and flux analysis, and case studies.
| Author | : Paul Shaw |
| Publisher | : Cambridge University Press |
| Total Pages | : 434 |
| Release | : 2013-10-24 |
| Genre | : Medical |
| ISBN | : 1107435617 |
The first comprehensive book on the subject, The Genetic Basis of Sleep and Sleep Disorders covers detailed reviews of the general principles of genetics and genetic techniques in the study of sleep and sleep disorders. The book contains sections on the genetics of circadian rhythms, of normal sleep and wake states and of sleep homeostasis. There are also sections discussing the role of genetics in the understanding of insomnias, hypersomnias including narcolepsy, parasomnias and sleep-related movement disorders. The final chapter highlights the use of gene therapy in sleep disorders. Written by genetic experts and sleep specialists from around the world, the book is up to date and geared specifically to the needs of both researchers and clinicians with an interest in sleep medicine. This book will be an invaluable resource for sleep specialists, neurologists, geneticists, psychiatrists and psychologists.
| Author | : Joseph Heitman |
| Publisher | : John Wiley & Sons |
| Total Pages | : 1161 |
| Release | : 2020-07-10 |
| Genre | : Medical |
| ISBN | : 1555819583 |
Fungi research and knowledge grew rapidly following recent advances in genetics and genomics. This book synthesizes new knowledge with existing information to stimulate new scientific questions and propel fungal scientists on to the next stages of research. This book is a comprehensive guide on fungi, environmental sensing, genetics, genomics, interactions with microbes, plants, insects, and humans, technological applications, and natural product development.
| Author | : J. Philipp Benz |
| Publisher | : Springer Nature |
| Total Pages | : 452 |
| Release | : 2020-10-28 |
| Genre | : Science |
| ISBN | : 3030499243 |
This fully revised third edition includes up-to-date topics and developments in the field, which has made tremendous strides since the publication of the second edition in 2004. Many novel techniques based on Next Generation Sequencing have sped up the analysis of fungi and major advances have been made in genome editing, leading to a deeper understanding of the genetics underlying cellular processes as well as their applicability. At the same time, the relevance of fungi is unbroken, both due to the serious threats to human health and welfare posed by fungal pests and pathogens, and to the many benefits that fungal biotechnology can offer for diverse emerging markets and processes that form the basis of the modern bioeconomy. With regard to these advances, the first section of this volume, Genetics, illustrates the basic genetic processes underlying inheritance, cell biology, metabolism and “lifestyles” of fungi. The second section, Biotechnology, addresses the applied side of fungal genetics, ranging from new tools for synthetic biology to the biotechnological potential of fungi from diverse environments. Gathering chapters written by reputed scientists, the book represents an invaluable reference guide for fungal biologists, geneticists and biotechnologists alike.
| Author | : Urs Albrecht |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 306 |
| Release | : 2010-01-23 |
| Genre | : Science |
| ISBN | : 1441912622 |
With the invitation to edit this volume, I wanted to take the opportunity to assemble reviews on different aspects of circadian clocks and rhythms. Although most c- tributions in this volume focus on mammalian circadian clocks, the historical int- duction and comparative clocks section illustrate the importance of various other organisms in deciphering the mechanisms and principles of circadian biology. Circadian rhythms have been studied for centuries, but only recently, a mole- lar understanding of this process has emerged. This has taken research on circadian clocks from mystic phenomenology to a mechanistic level; chains of molecular events can describe phenomena with remarkable accuracy. Nevertheless, current models of the functioning of circadian clocks are still rudimentary. This is not due to the faultiness of discovered mechanisms, but due to the lack of undiscovered processes involved in contributing to circadian rhythmicity. We know for example, that the general circadian mechanism is not regulated equally in all tissues of m- mals. Hence, a lot still needs to be discovered to get a full understanding of cir- dian rhythms at the systems level. In this respect, technology has advanced at high speed in the last years and provided us with data illustrating the sheer complexity of regulation of physiological processes in organisms. To handle this information, computer aided integration of the results is of utmost importance in order to d- cover novel concepts that ultimately need to be tested experimentally.
| Author | : David Moore |
| Publisher | : Cambridge University Press |
| Total Pages | : 611 |
| Release | : 2020-05-08 |
| Genre | : Science |
| ISBN | : 1108807844 |
The mysterious world of fungi is once again unearthed in this expansive second edition. This textbook provides readers with an all-embracing view of the kingdom fungi, ranging in scope from ecology and evolution, diversity and taxonomy, cell biology and biochemistry, to genetics and genomics, biotechnology and bioinformatics. Adopting a unique systems biology approach - and using explanatory figures and colour illustrations - the authors emphasise the diverse interactions between fungi and other organisms. They outline how recent advances in molecular techniques and computational biology have fundamentally changed our understanding of fungal biology, and have updated chapters and references throughout the book in light of this. This is a fascinating and accessible guide, which will appeal to a broad readership - from aspiring mycologists at undergraduate and graduate level to those studying related disciplines. Online resources are hosted on a complementary website.
| Author | : Lars Olof Björn |
| Publisher | : Springer |
| Total Pages | : 453 |
| Release | : 2015-01-02 |
| Genre | : Science |
| ISBN | : 1493914685 |
The new edition of this authoritative text provides an interdisciplinary treatise of all aspects of the interactions between light and the living world. It starts with a description of the physics of light, and how to deal with it in experiments and observations. The phenomena described in the rest of the book covers all organisms: how light is used by organisms for obtaining energy for life processes, for gathering information about the environment, and for communicating with others of the same or other species. The book also describes "bad" effects of light in causing disease or contributing to formation of environmental toxins. New techniques used by scientists to investigate life processes using light are also explored in the volume. Written by experts in the field, Photobiology: The Science of Life and Light, 3e is a valuable and accessible resource for both advanced undergraduates and established researchers.
| Author | : Robert A. Meyers |
| Publisher | : John Wiley & Sons |
| Total Pages | : 1259 |
| Release | : 2012-05-29 |
| Genre | : Science |
| ISBN | : 3527326820 |
Epigenetics is a term in biology referring to heritable traits that do not involve changes in the underlying DNA sequence of the organism. Epigenetic traits exist on top of or in addition to the traditional molecular basis for inheritance. The "epigenome" is a parallel to the word "genome," and refers to the overall epigenetic state of a cell. Cancer and stem cell research have gradually focused attention on these genome modifications. The molecular basis of epigenetics involves modifications to DNA and the chromatin proteins that associate with it. Methylation, for example, can silence a nearby gene and seems to be involved in some cancers. Epigenetics is beginning to form and take shape as a new scientific discipline, which will have a major impact on Medicine and essentially all fields of biology. Increasingly, researchers are unearthing links between epigenetics and a number of diseases. Although in recent years cancer has been the main focus of epigenetics, recent data suggests that epigenetic plays a critical role in psychology and psychopathology. It is being realized that normal behaviors such as maternal care and pathologies such as Schizophrenia and Alzheimer's might have an epigenetic basis. It is also becoming clear that nutrition and life experiences have epigenetic consequences. Discover more online content in the Encyclopedia of Molecular Cell Biology and Molecular Medicine.
| Author | : Tilo Strutz |
| Publisher | : Springer Vieweg |
| Total Pages | : 0 |
| Release | : 2015-12-16 |
| Genre | : Technology & Engineering |
| ISBN | : 9783658114558 |
The subject of data fitting bridges many disciplines, especially those traditionally dealing with statistics like physics, mathematics, engineering, biology, economy, or psychology, but also more recent fields like computer vision. This book addresses itself to engineers and computer scientists or corresponding undergraduates who are interested in data fitting by the method of least-squares approximation, but have no or only limited pre-knowledge in this field. Experienced readers will find in it new ideas or might appreciate the book as a useful work of reference. Familiarity with basic linear algebra is helpful though not essential as the book includes a self-contained introduction and presents the method in a logical and accessible fashion. The primary goal of the text is to explain how data fitting via least squares works. The reader will find that the emphasis of the book is on practical matters, not on theoretical problems. In addition, the book enables the reader to design own software implementations with application-specific model functions based on the comprehensive discussion of several examples. The text is accompanied with working source code in ANSI-C for fitting with weighted least squares including outlier detection. Among others the book covers following topics * fitting of linear and nonlinear functions with one- or multi-dimensional variables * weighted least-squares * outlier detection * evaluation of the fitting results * different optimisation strategies * combined fitting of different model functions * total least-squares approach with multi-dimensional conditions
