Fast Facts: Thrombotic Thrombocytopenic Purpura

Fast Facts: Thrombotic Thrombocytopenic Purpura
Author: M.A. Scully
Publisher: Karger Medical and Scientific Publishers
Total Pages: 61
Release: 2020-02-26
Genre: Medical
ISBN: 1912776804

Thrombotic thrombocytopenic purpura (TTP) is a rare disorder of the blood coagulation system. In most cases, a lack of the ADAMTS13 enzyme leads to an accumulation of ultra-large von Willebrand factor molecules in the plasma which, in turn, initiate the formation of microscopic thromboses in small blood vessels. TTP is a medical emergency. Timely diagnosis and urgent and effective management are vital – mortality in those untreated is in the region of 90%. The understanding of TTP pathogenesis has increased markedly in recent decades. It is now known that TTP is acquired (immunemediated) or congenital, and that the most common type – the acquired form – predominantly affects women in their 40s. It is also clear that the prompt delivery of plasma exchange saves lives. 'Fast Facts: Thrombotic Thrombocytopenic Purpura' sets out, in a clear and accessible format, the steps to suspecting, diagnosing and treating this potentially devastating disease. These steps are complemented by clear descriptions of the disease mechanism and epidemiology. Differential diagnosis, which is of the utmost importance for this disease, is explored in detail. Contents: • Disease overview • Clinical presentation • Differential diagnosis • Laboratory findings and diagnosis • Management

TTP

TTP
Author:
Publisher: Mack
Total Pages: 186
Release: 2018
Genre: Leipzig (Germany)
ISBN: 9781912339242

Photographs of a ping pong table located in a public athletic field across from the photographer's dorm in Leipzig, Germany. Shot at various times of day and in various seasons, and showing different protagonists each time. Winner of the 2018 MACK First Book Award.

Diagnostic Criteria in Autoimmune Diseases

Diagnostic Criteria in Autoimmune Diseases
Author: Yehuda Shoenfeld
Publisher: Springer Science & Business Media
Total Pages: 555
Release: 2010-06-08
Genre: Medical
ISBN: 1603272852

According to the Autoimmune Diseases Coordinating Committee (ADCC), between 14.7 and 23.5 million people in the USA – up to eight percent of the population are affected by autoimmune disease. Autoimmune diseases are a family of more than 100 chronic, and often disabling, illnesses that develop when underlying defects in the immune system lead the body to attack its own organs, tissues, and cells. In Handbook of Autoimmune Disease, the editors have gathered in a comprehensive handbook a critical review, by renowned experts, of more than 100 autoimmune diseases, divided into two main groups, namely systemic and organ-specific autoimmune diseases. A contemporary overview of these conditions with special emphasis on diagnosis is presented. Each chapter contains the essential information required by attending physicians as well as bench scientists to understand the definition of a specific autoimmune disease, the diagnostic criteria, and the treatment.

Hemolytic Uremic Syndrome and Thrombotic Thrombocytopenic Purpura

Hemolytic Uremic Syndrome and Thrombotic Thrombocytopenic Purpura
Author: Bernard S. Kaplan
Publisher: CRC Press
Total Pages: 608
Release: 1992-07-14
Genre: Medical
ISBN: 9780824786632

This reference presents detailed discussions of the history, pathology, pathophysiology, and approaches to treatment of the complicated, constantly evolving syndromes known as thrombotic thromocytopenic purpura (TTP), from many different points of view. Hemolytic Uremic syndrome and Thrombotic Thrombocytopenic Purpura offers: extensive analyses of the relationship between HUS and TTP; epidemiological studies of HUS from the UK, Canada, Asia, South Africa and Argentina; investigations of non-renal complications of HUS; perspectives on atypical HUS and post-transplantation HUS; delineations of the association between verotoxin and HUS, HUS and pregnancy, and HUS and cancer and cancer tharapy; information on HUS/TTP in HIV-infected patients; explications of the pathology and pathogenesis of HUS; and approaches to treatment of HUS, prognosis, and long-term follow-up.;In addition, it covers the history and pathogenesis of TTP, von Willebrand factor abnormalities in TTP and HUS, platelet agglutinating proteins in TTP, and the treatment of TTP.;With over 2000 literature citations and figures, this book is for nephrologists, hematologists, oncologists, paediatricians, pathologists, gastroenterologists, internists, endocrinologists, infectious disease specialists, neurologists, gynaecologists, microbiologists, surgeons, geneticsts, epidemiologists, radiologists, and medical school students in these disciplines.

Terrorism in Pakistan

Terrorism in Pakistan
Author: N. Elahi
Publisher: Bloomsbury Publishing
Total Pages: 285
Release: 2019-03-07
Genre: History
ISBN: 1838609245

Since the Soviet invasion of Afghanistan in 1979, Pakistan has faced the threat of terrorism in different forms and shapes. Yet in recent years the threat has taken on a new dimension. After 9/11 the US campaign against Osama bin Laden, al-Qaeda and the Taliban in Afghanistan led to a surge in unrest and violence in Pakistan. Al-Qaeda gained a foothold in tribal regions of Pakistan via their local supporters, the Tehreek-e-Taliban Pakistan (TTP), currently led by Mullah Fazlullah, who unleashed a new wave of terror across Pakistan. Since then, more than 60,000 Pakistanis have been killed as the result of TTP-orchestrated insurgency and terrorist attacks and Pakistan's society, economy and its international image have suffered at the hands of TTP and its affiliated groups. As a result of several military operations many TTP leaders have taken refuge in Afghanistan where they have joined hands with the terrorist group ISIS, the so-called Islamic State, or Daesh by its local name. Pakistan's nascent democratic set-up, in the form of the government of Nawaz Sharif, is struggling to curb this menace. This is the first book to cover all aspects of terrorism in Pakistan and to reveal the composition, ideology, approaches and strengths of TTP and its affiliates. It is essential reading for policy-makers, strategists, security experts and students to understand the intricate contours and dimensions of insurgency and terrorism within Pakistan.

Case Studies in Emergency Medicine

Case Studies in Emergency Medicine
Author: Colin G. Kaide
Publisher: Springer Nature
Total Pages: 683
Release: 2019-11-14
Genre: Medical
ISBN: 3030224457

This book contains a variety of medical case studies from actual patients presenting to the emergency department. It includes not only typical cases that present to the ED but also less common, yet very important cases that one can't afford to miss. Each chapter begins with a case – or set of cases with typical and atypical aspects – of the disease in question. This is followed by high-value learning points on the condition with introductory/background points, physiology and pathophysiology of the disease, how to make the diagnosis, and finally how to initiate treatment. The cases provide expert discussion with tips and tricks, personal experience with management of each of the cases, and a follow-up description of the outcome of the cases to provide the reader with closure. To supplement each case study, all 67 chapters include a pattern recognition component that identifies the key diagnostic features of the disease discussed. The chapters conclude with a summary of the diagnostic and treatment details of each condition. Using a concise, easy-to-read, bulleted format, the book helps readers to learn, evaluate, adopt new practices, right now (LEARN). Emergency Medicine Case Studies - LEARNing Rounds: Learn, Evaluate, Adopt, Right Now is an essential resource for a variety of emergency medicine clinicians including experienced physicians, residents, physician assistants, nurse practitioners, nurses, and medical students rotating in the emergency department. Finally, this book can be used as a basis for small group discussions, especially in emergency medicine training programs.

Guardians of God

Guardians of God
Author: Mona Kanwal Sheikh
Publisher: Oxford University Press
Total Pages: 250
Release: 2016-09-22
Genre: Political Science
ISBN: 0199089809

This book is an account of the emergence and key events related to the origin and expansion of Pakistani Taliban since 2001, with a focus on the role of religion in their actions, policies and worldviews. The author brings to light rare insight into the ideological basis of Pakistani Taliban, drawing upon first-hand research comprising participant observation, interviews, content analysis of organizational literature and Talibani communications, such as recruitment videos, recorded speeches, leaflets and pamphlets, jihadi anthems and press releases to the local media. The book demonstrates how religion simultaneously appears as an object to be defended, as a threat, as the purpose of violence, as the source of rules and limitations on violent action and as the source of motivational imagery and myths. Going into an analysis of just what role religion plays in violent activities of this group and how does it do so, the author shows that Talibani narratives are both secular and religious at the same time, contradicting a clear-cut divide between religious and secular motivations for violence. The book advocates against extreme positions that accord religion either a primary or a negligent position in explaining the raison d’être of Pakistani Taliban. It makes a plea for more informed and empathetic approach instead of the purely militaristic stance towards extremism, which has only helped it grow in the past.

Practical Emergency Resuscitation and Critical Care

Practical Emergency Resuscitation and Critical Care
Author: Kaushal Shah
Publisher: Cambridge University Press
Total Pages: 655
Release: 2023-10-31
Genre: Medical
ISBN: 1009055623

The second edition of a succinct and portable text reviewing the clinical approach to emergency medicine and critical care.

Spinoza's Political Treatise

Spinoza's Political Treatise
Author: Yitzhak Y. Melamed
Publisher: Cambridge University Press
Total Pages: 465
Release: 2018-08-02
Genre: Philosophy
ISBN: 1316762157

Spinoza's Political Treatise constitutes the very last stage in the development of his thought, as he left the manuscript incomplete at the time of his death in 1677. On several crucial issues - for example, the new conception of the 'free multitude' - the work goes well beyond his Theological Political Treatise (1670), and arguably presents ideas that were not fully developed even in his Ethics. This volume of newly commissioned essays on the Political Treatise is the first collection in English to be dedicated specifically to the work, ranging over topics including political explanation, national religion, the civil state, vengeance, aristocratic government, and political luck. It will be a major resource for scholars who are interested in this important but still neglected work, and in Spinoza's political philosophy more generally.

Holland-Frei Cancer Medicine

Holland-Frei Cancer Medicine
Author: Robert C. Bast, Jr.
Publisher: John Wiley & Sons
Total Pages: 2004
Release: 2017-03-10
Genre: Medical
ISBN: 111900084X

Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates