The transonic scaling effect of shock wave/boundary-layer interaction on a quasi, two-dimensional C-141 airfoil was investigated. Data were obtained from the AEDC Propulsion Wind Tunnel Facility Aerodynamic Wind Tunnel (4T) and Propulsion Wind Tunnel (16T) and from the NASA Marshall Space FLIGHT Center High Reynolds Number Tunnel with 6-in.- and 24-in.-chord airfoils for a range 0.70 to 0.85. In addition to the investigation of the effect of Reynolds number on the airfoil pressure distribution, the effect of fixed boundary-layer transition was evaluated using grit-type transition strips on the airfoil surface. The significant parameters affecting the shock wave/boundary-layer interaction are identified. The data indicate that simulation of higher Reynolds number data on the C-141 airfoil model is feasible by use of a fixed-boundary-layer-transition strip. (Author).