Transducing The Genome
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Author | : Gary Zweiger |
Publisher | : McGraw Hill Professional |
Total Pages | : 298 |
Release | : 2001 |
Genre | : Medical |
ISBN | : 9780071387613 |
This text provides a behind-the-scenes look at the sequencing of the human genome project and the birth of the science of genomics. It explains genomics as an information science and traces its history back further than standard histories and news accounts to the early visionaries.
Author | : Zweiger |
Publisher | : |
Total Pages | : |
Release | : |
Genre | : |
ISBN | : 9780070582361 |
Author | : National Research Council |
Publisher | : National Academies Press |
Total Pages | : 171 |
Release | : 1999-10-13 |
Genre | : Science |
ISBN | : 0309066344 |
How small can a free-living organism be? On the surface, this question is straightforward-in principle, the smallest cells can be identified and measured. But understanding what factors determine this lower limit, and addressing the host of other questions that follow on from this knowledge, require a fundamental understanding of the chemistry and ecology of cellular life. The recent report of evidence for life in a martian meteorite and the prospect of searching for biological signatures in intelligently chosen samples from Mars and elsewhere bring a new immediacy to such questions. How do we recognize the morphological or chemical remnants of life in rocks deposited 4 billion years ago on another planet? Are the empirical limits on cell size identified by observation on Earth applicable to life wherever it may occur, or is minimum size a function of the particular chemistry of an individual planetary surface? These questions formed the focus of a workshop on the size limits of very small organisms, organized by the Steering .Group for the Workshop on Size Limits of Very Small Microorganisms and held on October 22 and 23, 1998. Eighteen invited panelists, representing fields ranging from cell biology and molecular genetics to paleontology and mineralogy, joined with an almost equal number of other participants in a wide-ranging exploration of minimum cell size and the challenge of interpreting micro- and nano-scale features of sedimentary rocks found on Earth or elsewhere in the solar system. This document contains the proceedings of that workshop. It includes position papers presented by the individual panelists, arranged by panel, along with a summary, for each of the four sessions, of extensive roundtable discussions that involved the panelists as well as other workshop participants.
Author | : Frederic Bushman |
Publisher | : CSHL Press |
Total Pages | : 472 |
Release | : 2002 |
Genre | : Medical |
ISBN | : 9780879696214 |
This book is about mobile genes—the transfer of DNA between unrelated cells. It discusses the machinery of gene transfer and its wide-ranging biological and health consequences. Mobile DNA makes possible the development of antibiotic resistance in microbes, the conversion of harmless to pathogenic bacteria, and the triggering of cancerous growth in cells. It also contributes to human evolution. This well-illustrated volume contains an up-to-date account of a topic now seen as increasingly important, and will be invaluable for both working scientists and as a textbook for advanced courses.
Author | : Edward A. Birge |
Publisher | : Springer Science & Business Media |
Total Pages | : 432 |
Release | : 2013-03-14 |
Genre | : Science |
ISBN | : 1475719957 |
Bacterial genetics has become one of the cornerstones of basic and applied microbiology and has contributed key knowledge for many of the fundamental advances of modern biology. The second edition of this comprehensive yet concise text, first published in 1981, has been thoroughly updated and redesigned to account for new developments in this rapidly expanding field. All of the major topics in modern bacterial and bacteriophage genetics are presented, among them mutations and mutagenesis, genetics of T4 bacteriophage and other intemperate and temperate phages, transduction, transformation, conjugation and plasmids, recombination and repair, probability laws for prokaryote cultures, as well as applied bacterial genetics.
Author | : Royal Society (Great Britain) |
Publisher | : |
Total Pages | : |
Release | : 2013 |
Genre | : Genomes |
ISBN | : 9781782520184 |
Author | : Ambikanandan Misra |
Publisher | : Elsevier |
Total Pages | : 686 |
Release | : 2010-09-09 |
Genre | : Science |
ISBN | : 0123849659 |
Delivery of therapeutic proteomics and genomics represent an important area of drug delivery research. Genomics and proteomics approaches could be used to direct drug development processes by unearthing pathways involved in disease pathogenesis where intervention may be most successful. This book describes the basics of genomics and proteomics and highlights the various chemical, physical and biological approaches to protein and gene delivery. Covers a diverse array of topics from basic sciences to therapeutic applications of proteomics and genomics delivery Of interest to researchers in both academia and industry Highlights what’s currently known and where further research is needed
Author | : David R. Harper |
Publisher | : Springer Nature |
Total Pages | : 1376 |
Release | : 2021-01-30 |
Genre | : Medical |
ISBN | : 3319419862 |
This first major reference work dedicated to the mannifold industrial and medical applications of bacteriophages provides both theoretical and practical insights into the emerging field of bacteriophage biotechnology. The book introduces to bacteriophage biology, ecology and history and reviews the latest technologies and tools in bacteriophage detection, strain optimization and nanotechnology. Usage of bacteriophages in food safety, agriculture, and different therapeutic areas is discussed in detail. This book serves as essential guide for researchers in applied microbiology, biotechnology and medicine coming from both academia and industry.
Author | : Arcady R. Mushegian |
Publisher | : Elsevier |
Total Pages | : 276 |
Release | : 2010-07-20 |
Genre | : Science |
ISBN | : 0080546099 |
This book provides an overview of computational analysis of genes and genomes, and of some most notable findings that come out of this work. Foundations of Comparative Genomics presents a historical perspective, beginning with early analysis of individual gene sequences, to present day comparison of gene repertoires encoded by completely sequenced genomes. The author discusses the underlying scientific principles of comparative genomics, argues that completion of many genome sequences started a new era in biology, and provides a personal view on several state-of-the-art issues, such as systems biology and whole-genome phylogenetic reconstructions. This book is an essential reference for researchers and students in computational biology, evolutionary biology, and genetics. Presents an historic overview of genome biology and its achievements Includes topics not covered in other books such as minimal and ancestral genomes Discusses the evolutionary resilience of protein-coding genes and frequent functional convergence at the molecular level Critically reviews horizontal gene transfer and other contentious issues Covers comparative virology as a somewhat overlooked foundation of modern genome science
Author | : |
Publisher | : Elsevier |
Total Pages | : 319 |
Release | : 2007-02-27 |
Genre | : Science |
ISBN | : 0080475108 |
The critically acclaimed laboratory standard for more than fifty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with over 400 volumes (all of them still in print), the series contains much material still relevant today—truly an essential publication for researchers in all fields of life sciences. This new volume presents methods related to the use of bacterial genetics for genomic engineering. The book includes sections on strain collections and genetic nomenclature; transposons; and phage.