TOXICOLOGY OF THE EYE

TOXICOLOGY OF THE EYE
Author: W. Morton Grant
Publisher: Charles C Thomas Publisher
Total Pages: 1619
Release: 1993-01-01
Genre: Eye
ISBN: 0398082154

The purpose of this book is to present a synopsis of what is known about substances that have toxic properties injurious to the eyes, disturbing to vision, or affecting eyes in other unwanted ways. The coverage is truly comprehensive, encompassing local and systemic, acute and chronic, human and veterinary toxicology of the eye. The text summarizes mechanisms of injury, treatments, and other relevant knowledge for more than 3000 alphabetized substances - essentially all those on which public information is available. Also described are systemic side effects of ophthalmologic drugs, treatment of chemical burns of the eyes, and testing methods and species specificity for toxic effects on the eyes. Facilitating access to this prodigious amount of information is a large index that cross-references substances and effects, including numerous synonyms. This monumental work is a truly definitive text and a highly useful reference book that should be available to every ophthalmologist, emergency room, and medical library.

Toxicology of the Eye

Toxicology of the Eye
Author: Walter Morton Grant
Publisher: Charles C Thomas Pub Limited
Total Pages: 1608
Release: 1993-01-01
Genre: Medical
ISBN: 9780398058609

Assessing Ocular Toxicology in Laboratory Animals

Assessing Ocular Toxicology in Laboratory Animals
Author: Andrea B Weir
Publisher: Springer Science & Business Media
Total Pages: 327
Release: 2012-12-04
Genre: Medical
ISBN: 1627031642

Ocular toxicity is routinely assessed in toxicology studies conducted for regulatory purposes. Ocular anatomy and physiology and the assessment of ocular toxicity itself can be challenging to scientists involved in the safety assessment of pharmaceuticals, pesticides and other agents. Anatomical and physiological differences between species can impact the nature of ocular effects observed following intended or unintended exposure of ocular tissues to xenobiotics. Ocular Toxicity in Laboratory Animals provides a concise reference addressing ocular anatomy and physiology across species that will enhance the design and interpretation of toxicology studies conducted for regulatory purposes. The book provides an overview of routine and advanced techniques that are used to assess ocular toxicity including slit lamp biomicroscopy, indirect ophthalmoscopy, electrophysiology and imaging methods for the anterior and posterior segments of the eye. Additionally, the book defines the regulatory expectations for pharmaceuticals intended to treat ocular diseases and for other non-pharmaceutical regulated chemicals. With contributions from experts in the field, Ocular Toxicity in Laboratory Animals is an authoritative, accessible guide for toxicologists and other scientists involved in conducting toxicology studies for regulatory purposes and/or reviewing data from such studies.

Ophthalmic Toxicology

Ophthalmic Toxicology
Author: G. C. Y. Chiou
Publisher: CRC Press
Total Pages: 379
Release: 1999-07-01
Genre: Medical
ISBN: 1439809984

Thoroughly revised and updates, this new edition of Ophthalmic Toxicology retains its uniqueness in covering all aspects of ophthalmic toxicology. With chapters from leading authorities incorporating the latest developments in the field, including a new chapter on the molecular basis of ophthalmic toxicity, this edition covers such topics as: *t

Toxicology of the Eye

Toxicology of the Eye
Author: Walter Morton Grant
Publisher: Charles C. Thomas Publisher
Total Pages: 1230
Release: 1974
Genre: Medical
ISBN:

Drug-Induced Ocular Side Effects: Clinical Ocular Toxicology

Drug-Induced Ocular Side Effects: Clinical Ocular Toxicology
Author: Frederick T. Fraunfelder
Publisher: Elsevier Health Sciences
Total Pages: 597
Release: 2020-06-21
Genre: Medical
ISBN: 0323674011

Written by global experts in the field of chemical- and drug-related ocular problems, Drug-Induced Ocular Side Effects, 8th Edition, provides need-to-know information on all aspects of ocular toxicology in one concise reference. This best-selling, user-friendly resource features a templated format, numerous full-color illustrations, and sweeping content updates throughout – all designed to eliminate uncertainty and ensure accurate diagnosis and treatment guidance. Provides comprehensive coverage of drugs’ generic and trade names, primary uses, ocular and systemic side effects, and clinical significance. Features a unique side effect index, a new concise paperback format for portability, and clinical photos of ocular symptoms of adverse drug reactions. Covers dozens of new drugs used in the U.S. and internationally, as well as extensive updates to drug registry information to ensure access to the latest data. Includes expanded sections on how to follow patients with visual adverse drug reactions to chloroquine, hydroxychloroquine, isotretinoin, ethambutol, and more. Guidelines can be copied to use as patient handouts. Offers extensive discussions of principles of therapy, ocular drug delivery, methods to evaluate drug-induced visual side effects, and the role of electrophysiology and psychophysics. Provides the WHO classification system to help you determine whether a particular side effect is certain, probable, or likely to occur. Ideal for ophthalmologists, optometrists, and busy clinicians in primary care, emergency medicine, and more – anyone who needs quick, on-the-spot consultation on ocular toxicology.

Ocular Toxicology

Ocular Toxicology
Author: Keith Green
Publisher: Springer Science & Business Media
Total Pages: 365
Release: 2012-12-06
Genre: Medical
ISBN: 1461518873

On behalf of the editorial board and the organizing committee of the 4th congress of the International Society of Ocular Toxicology (I SOT), held in AnnecyNeyrier du Lac, France, October 9 -13, 1994, we are pleased to present to the ocular toxicology community this indexed volume of our congress proceedings. The 4th congress was designed primarily to facilitate and update the knowledge in ocular electrophysiology and ocular pharmacokinetics, in both the clinical and preclinical aspects. The outcome of this 4th congress, established in this volume, is a useful contribution to the meth odology in both fields and will hopefully assist in the evaluation and interpretation of ocular findings recorded in animal studies on drugs and other chemicals, in order to protect human health. Undoubtedly, work on the mechanisms of ocular toxicology in the process of pharmaceutical development must continue and these proceedings, embodying the presented papers, will add to the data base. The editors, the congress organizing committee and the members of the International Society of Ocular Toxicology thank the speakers who gave their time, knowledge, and expertise to assist us in this project. The following manuscripts contain the main substance of each of the platform presentations and, in some cases, much more. Moreover, our thanks go to all the participants coming from a range of background- regulatory, academic and industrial -for their attention and excellent contributions during the discussion.