Some Chemicals Present in Industrial and Consumer Products, Food and Drinking-water

Some Chemicals Present in Industrial and Consumer Products, Food and Drinking-water
Author: IARC Working Group on the Evaluation of Carcinogenic Risks to Humans
Publisher: IARC Monographs on the Evaluat
Total Pages: 0
Release: 2013
Genre: Medical
ISBN: 9789283213246

This volume of the IARC Monographs provides an assessment of the carcinogenicity of 18 chemicals present in industrial and consumer products or food (natural constituents, contaminants, or flavorings) or occurring as water-chlorination by-products. The compounds evaluated include the widely used plasticizer di(2-ethylhexyl) phthalate and the food contaminant 4-methylimidazole. In view of the limited agent-specific information available from epidemiological studies, the IARC Monographs Working Group relied mainly on carcinogenicity bioassays, and mechanistic and other relevant data to evaluate the carcinogenic hazards to humans exposed to these agents.

Toxicological Profile for DI (2-Ethylhexyl) Phthalate (DEHP)

Toxicological Profile for DI (2-Ethylhexyl) Phthalate (DEHP)
Author:
Publisher:
Total Pages: 161
Release: 2001-02
Genre:
ISBN: 9780756708351

This report provides information about Di (2-Ethylhexyl) Phthalate (DEHP) & the human health effects of exposure. This chemical has been found in many sites identified by the EPA for long-term Federal cleanup activities. The report includes a Public Health Statement which explains the toxicologic properties of DEHP in a nontechnical, Q&A format, & a review of the general health effects observed following exposure; a description of health effects; how the chemical can affect children; & information on its chemical & physical properties, production, use & disposal, potential for human exposure, analytical methods, & regulations & advisories.

Phthalates and Cumulative Risk Assessment

Phthalates and Cumulative Risk Assessment
Author: National Research Council
Publisher: National Academies Press
Total Pages: 208
Release: 2009-01-19
Genre: Nature
ISBN: 0309128412

People are exposed to a variety of chemicals throughout their daily lives. To protect public health, regulators use risk assessments to examine the effects of chemical exposures. This book provides guidance for assessing the risk of phthalates, chemicals found in many consumer products that have been shown to affect the development of the male reproductive system of laboratory animals. Because people are exposed to multiple phthalates and other chemicals that affect male reproductive development, a cumulative risk assessment should be conducted that evaluates the combined effects of exposure to all these chemicals. The book suggests an approach for cumulative risk assessment that can serve as a model for evaluating the health risks of other types of chemicals.