Mechanisms of Morphogenesis

Mechanisms of Morphogenesis
Author: Jamie A. Davies
Publisher: Academic Press
Total Pages: 417
Release: 2013-02-18
Genre: Science
ISBN: 0124157572

Morphogenesis is the set of processes that generate shape and form in the embryo--an important area within developmental biology. An exciting and up-to-the-minute account of the very latest research into the factors that create biological form, Mechanisms of Morphogenesis, second edition is a text reference on the mechanisms of cell and tissue morphogenesis in a diverse array of organisms, including prokaryotes, animals, plants and fungi. By combining hard data with computer modeling, Mechanisms of Morphogenesis, second edition equips readers with a much broader understanding of the scope of modern research than is otherwise available. The book focuses on the ways in which the genetic program is translated to generate cell shape, to direct cell migration, and to produce the shape, form and rates of growth of the various tissues. Each topic is illustrated with experimental data from real systems, with particular reference to gaps in current knowledge and pointers to future - Includes over 200 four-color figures - Offers an integrated view of theoretical developmental biology and computer modelling with laboratory-based discoveries - Covers experimental techniques as a guide to the reader - Organized around principles and mechanisms, using them to integrate discoveries from a range of organisms and systems

Morphogenesis in Plant Tissue Cultures

Morphogenesis in Plant Tissue Cultures
Author: Woong-Young Soh
Publisher: Springer Science & Business Media
Total Pages: 522
Release: 2013-11-11
Genre: Science
ISBN: 9401592535

This book presents a detailed analysis of up-to-date literature on in vitro morphogenesis at cell, tissue, organ, and whole plant levels. Its driving force is the substantial advances made in the field of morphogenesis in tissue cultures during the last 25 years.

Branching Morphogenesis

Branching Morphogenesis
Author: Jamie Davies
Publisher: Springer Science & Business Media
Total Pages: 255
Release: 2007-03-20
Genre: Science
ISBN: 0387308733

Branching morphogenesis, the creation of branched structures in the body, is a key feature of animal and plant development. This book brings together, for the first time, expert researchers working on a variety of branching systems to present a state-of-the-art view of the mechanisms that control branching morphogenesis. Systems considered range from single cells, to blood vessel and drainage duct systems to entire body plans, and approaches range from observation through experiment to detailed biophysical modelling. The result is an integrated overview of branching.

Extracellular Matrix in Development

Extracellular Matrix in Development
Author: Douglas W. DeSimone
Publisher: Springer Science & Business Media
Total Pages: 260
Release: 2013-03-15
Genre: Science
ISBN: 3642359353

Cells in the developing embryo depend on signals from the extracellular environment to help guide their differentiation. An important mediator in this process is the extracellular matrix – secreted macromolecules that interact to form large protein networks outside the cell. During development, the extracellular matrix serves to separate adjacent cell groups, participates in establishing morphogenic gradients, and, through its ability to interact directly will cell-surface receptors, provides developmental clocks and positional information. This volume discusses how the extracellular matrix influences fundamental developmental processes and how model systems can be used to elucidate ECM function. The topics addressed range from how ECM influences early development as well as repair processes in the adult that recapitulate developmental pathways.

Developmental Biology: A Very Short Introduction

Developmental Biology: A Very Short Introduction
Author: Lewis Wolpert
Publisher: Oxford University Press
Total Pages: 153
Release: 2011-08-25
Genre: Science
ISBN: 0199601194

"A concise account of what we know about development discusses the first vital steps of growth and explores one of the liveliest areas of scientific research."--P. [2] of cover.

Single-Cell-Based Models in Biology and Medicine

Single-Cell-Based Models in Biology and Medicine
Author: Alexander Anderson
Publisher: Springer Science & Business Media
Total Pages: 346
Release: 2007-08-08
Genre: Mathematics
ISBN: 376438123X

Aimed at postgraduate students in a variety of biology-related disciplines, this volume presents a collection of mathematical and computational single-cell-based models and their application. The main sections cover four general model groupings: hybrid cellular automata, cellular potts, lattice-free cells, and viscoelastic cells. Each section is introduced by a discussion of the applicability of the particular modelling approach and its advantages and disadvantages, which will make the book suitable for students starting research in mathematical biology as well as scientists modelling multicellular processes.

Pattern Formation in Morphogenesis

Pattern Formation in Morphogenesis
Author: Vincenzo Capasso
Publisher: Springer Science & Business Media
Total Pages: 283
Release: 2012-10-02
Genre: Mathematics
ISBN: 3642201644

Pattern Formation in Morphogenesis is a rich source of interesting and challenging mathematical problems. The volume aims at showing how a combination of new discoveries in developmental biology and associated modelling and computational techniques has stimulated or may stimulate relevant advances in the field. Finally it aims at facilitating the process of unfolding a mutual recognition between Biologists and Mathematicians of their complementary skills, to the point where the resulting synergy generates new and novel discoveries. It offers an interdisciplinary interaction space between biologists from embryology, genetics and molecular biology who present their own work in the perspective of the advancement of their specific fields, and mathematicians who propose solutions based on the knowledge grasped from biologists.

Molecular Force Sensors

Molecular Force Sensors
Author: Rachel Bender
Publisher: American Chemical Society
Total Pages: 201
Release: 2022-03-09
Genre: Science
ISBN: 084129917X

Molecular force sensors are a powerful tool for studying the mechanics of cells. These sensors not only provide information on the general mechanical behavior of cells but also can help elucidate the mechanical markers of disease formation and progression. For example, can we use cell mechanics as a biomarker to diagnose cancer? What are the mechanics associated with immune system function? Can cell mechanics be used to better understand the effect of drug treatments? The number of available questions in the field of mechanobiology is endless. After reading this e-book, you will be equipped with the information needed to begin designing your own molecular force sensors, and to begin answering the multitude of questions surrounding cell mechanobiology.

Morphogenesis

Morphogenesis
Author: Jonathan B. L. Bard
Publisher: Cambridge University Press
Total Pages: 314
Release: 1992-07-02
Genre: Medical
ISBN: 9780521436120

This book, first published in 1990, provides an overview of the events and mechanisms of morphogenesis.

Tissue Remodeling and Epithelial Morphogenesis

Tissue Remodeling and Epithelial Morphogenesis
Author:
Publisher: Elsevier
Total Pages: 263
Release: 2009-09-07
Genre: Science
ISBN: 0080956831

For more than 30 years, Current Topics in Developmental Biology has provided a forum for dissemination and discussion of new ideas and thought in developmental biology. Bringing together a series of articles on the structural, functional, and developmental characteristics of epithelials, this thematic volume represents a timely and valuable contribution to an exciting and multidisciplinary field of study. Because defects in epithelial function and growth control play a major role in human disease—cancerous tumors, spina bifida, cardiac malformations, for example—this volume will be of particular interest to researchers working in cancer drug design and development and those working in therapeutic areas to treat developmental abnormalities. Coverage of current research findings and thought on cell-cell and cell-extracellular matrix interactions gives researchers a better understanding of the processes of remodeling and morphogenesis, which are critical to the development of drugs aimed at disrupting the early formation and proliferation of cancerous tumors Inclusion of chapters that discuss the most contemporary thought on cell polarity and tissue morphogenesis, providing researchers with a better understanding of the control of cellular organization and polarity (particularly important to researchers who are developing treatments for developmental abnormalities and those working in cancer drug development) Use of a variety of animal models, allowing researchers to compare and contrast the molecular mechanisms that underlie cell-cell and cell-extracelluar matrix interactions in a variety of research models