Therapeutic Strategies To Spinal Cord Injury
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Author | : Pavla Jendelova |
Publisher | : MDPI |
Total Pages | : 239 |
Release | : 2018-11-29 |
Genre | : Electronic books |
ISBN | : 3038974064 |
This book is a printed edition of the Special Issue "Therapeutic Strategies to Spinal Cord Injury" that was published in IJMS
Author | : Pavla Jendelova |
Publisher | : |
Total Pages | : |
Release | : 2018 |
Genre | : |
ISBN | : 9783038974079 |
This Special Issue gathers eight research articles covering a broad range of strategies on how to combat spinal cord injuries, from searching for therapeutic target molecules, tackling inflammatory reactions, utilizing cell therapy or cell-based products, combined strategies for axonal plasticity assessment, and prevention of post-surgical epidural adhesions. Moreover, four reviews cover recent findings about the role of stress-activated protein kinases in SCI; progress in stem cell therapies; the mechanisms and benefits of activity-based physical rehabilitation therapies with adjuvant testosterone; and, finally, translational regenerative therapies for chronic spinal cord injury.
Author | : Giuseppe Perale |
Publisher | : Woodhead Publishing |
Total Pages | : 346 |
Release | : 2019-10-30 |
Genre | : Medical |
ISBN | : 0081028083 |
Spinal Cord Injury (SCI) Repair Strategies provides researchers the latest information on potential regenerative approaches to spinal cord injury, specifically focusing on therapeutic approaches that target regeneration, including cell therapies, controlled drug delivery systems, and biomaterials. Dr. Giuseppe Perale and Dr. Filippo Rossi lead a team of authoritative authors in academia and industry in this innovative reference on the field of regenerative medicine and tissue engineering. This book presents all the information readers need to understand the current and potential array of techniques, materials, applications and their benefits for spinal cord repair. Covers current and future repair strategies for spinal cord injury repair Focuses on key research trends, clinics, biology and engineering Provides fundamentals on regenerative engineering and tissue engineering
Author | : Alexius Josephus Lankhorst |
Publisher | : |
Total Pages | : 165 |
Release | : 2000 |
Genre | : |
ISBN | : 9789039323793 |
Author | : Hongyun Huang |
Publisher | : Nova Science Publishers |
Total Pages | : 0 |
Release | : 2015 |
Genre | : Nervous system |
ISBN | : 9781634636001 |
Neurorestoratology is one of the most important disciplines in modern medicine and is also the most important discipline in neuroscience. Its core aim is to restore, promote and maintain the integrity of impaired or lost neuronal functions and/or structures by using novel cell-based comprehensive neurorestorative strategies. This book is the first and a unique one that systematically expounds the main aspects of neurorestoratology, which includes three sections with 22 chapters in two volumes. It systematically elaborates CNS neurorestorable theory and neurorestorative mechanisms. It firstly comprehends the Neurorestorative Process as a whole and Neurorestorative law. It fully describes all neurorestorative strategies and their continuing clinical progresses and achievements, especially the cell-based comprehensive neurorestorative strategies.
Author | : Sue Ann Sisto |
Publisher | : Elsevier Health Sciences |
Total Pages | : 608 |
Release | : 2008-01-31 |
Genre | : Medical |
ISBN | : 0323063020 |
From a hospital admittance to discharge to outpatient rehabilitation, Spinal Cord Injuries addresses the wide spectrum of rehabilitation interventions and administrative and clinical issues specific to patients with spinal cord injuries. Comprehensive coverage includes costs, life expectancies, acute care, respiratory care, documentation, goal setting, clinical treatment, complications, and activities of daily living associated with spinal cord patients. In addition to physical therapy interventions and family education components, this resource includes content on incidence, etiology, diagnosis, and clinical features of spinal cord injury. Case Studies with clinical application thinking exercises help you apply knowledge from the book to real life situations. Thoroughly referenced, evidence-based content provides the best evidence for treatment based on the most current research. Tables and boxes throughout each chapter organize and summarize important information for quick reference. Clinical Note boxes provide at-a-glance access to helpful tips. Over 500 clinical photos, line drawings, radiographs, and more bring important concepts to life. Highly respected experts in spinal cord injury rehabilitation, editors Sue Ann Sisto, Erica Druin, and Martha Sliwinski, provide authoritative guidance on the foundations and principles of practice for spinal cord injury. Companion DVD includes video clips of the techniques described throughout the book that demonstrate how to apply key concepts to practice.
Author | : José Juan Antonio Ibarra Arias |
Publisher | : BoD – Books on Demand |
Total Pages | : 173 |
Release | : 2019-11-27 |
Genre | : Medical |
ISBN | : 1789841615 |
Spinal cord injury (SCI) is one of the main pathologies causing significant loss of neurological function. Therefore, a variety of pharmacological and non-pharmacological therapies are the aims of several studies. To provide the best care, it is important to know and understand the therapeutic approaches that have shown important progress in this topic. This book contains eight chapters that are divided into three sections: Introduction, Pharmacological Therapies, and Non-Pharmacological Therapies. The authors of the chapters deal with the pathophysiology of SCI, the effect of antioxidant and immunosuppressive agents, stem cell-based therapies, the use of cultured cells for transference or transplantation, and the application of non-invasive modalities (transcutaneous electrical spinal cord stimulation, etc.) for SCI rehabilitation.
Author | : Susan J. Harkema |
Publisher | : |
Total Pages | : 200 |
Release | : 2011 |
Genre | : Medical |
ISBN | : 0195342089 |
Physical rehabilitation for walking recovery after spinal cord injury is undergoing a paradigm shift. Therapy historically has focused on compensation for sensorimotor deficits after SCI using wheelchairs and bracing to achieve mobility. With locomotor training, the aim is to promote recovery via activation of the neuromuscular system below the level of the lesion. What basic scientists have shown us as the potential of the nervous system for plasticity, to learn, even after injury is being translated into a rehabilitation strategy by taking advantage of the intrinsic biology of the central nervous system. While spinal cord injury from basic and clinical perspectives was the gateway for developing locomotor training, its application has been extended to other populations with neurologic dysfunction resulting in loss of walking or walking disability.
Author | : Heidi Fuller |
Publisher | : BoD – Books on Demand |
Total Pages | : 332 |
Release | : 2016-08-17 |
Genre | : Medical |
ISBN | : 9535124978 |
Restoration of motor function following spinal cord injury is a complex and challenging task. By reviewing emerging cellular, pharmacological, rehabilitative, as well as surgical approaches, this book seeks to highlight promising therapeutic strategies for the repair and regeneration of motor circuitry. The multidisciplinary nature of these approaches illustrates various routes to bridging the gap between the bench and the bedside and to identify the challenges that must be overcome in order to bring about a viable therapeutic strategy for spinal cord injury patients.
Author | : Milan R. Dimitrijevic |
Publisher | : OUP USA |
Total Pages | : 337 |
Release | : 2012-01-12 |
Genre | : Medical |
ISBN | : 0199746508 |
Following injury or disease, neural circuitry can be altered to varying degrees leading to highly individualized characteristics that may or may not resemble original function. In addition, lost or partially damaged circuits and the effects of biological recovery processes coupled with learned compensatory strategies create a new neuroanatomy with capabilities that are often not functional or may interfere with daily life. To date, the majority of approaches used to treat neurological dysfunction have focused on the replacement of lost or damaged function, usually through the suppression of surviving neural activity and the application of mechanical assistive devices. Restorative Neurology of Spinal Cord Injury offers a different and novel approach. Focusing on the spinal cord and its role in motor control, the book details the clinical and neurophysiological assessment process and methods developed throughout the past half century by basic and clinical scientists. Then, through the use of specialized clinical and neurophysiological testing methods, conduction and processing performed within the surviving neural circuitry is examined and characterized in detail. Based on the results of such assessment, treatment strategies, also described in this book, are applied to augment, rather than replace, the performance of surviving neural circuitry and improve the functional capacity of people who have experienced injury to their spinal cords.