Theory Of Particulate Process
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Author | : Alan Ranodolph |
Publisher | : Elsevier |
Total Pages | : 386 |
Release | : 2012-12-02 |
Genre | : Science |
ISBN | : 0323161812 |
Theory of Particulate Processes: Analysis and Techniques of Continuous Crystallization, Second Edition covers the numerous population balance-based particulate studies. This edition emerged from the notes for an industrial short course on crystallization. This book is divided into 10 chapters and begins with an outline of the methods for representation of particle distributions and a systematic approach to the predictive modeling of processes where there is a need to characterize distributions in time and space and by some identifying property. The succeeding chapters provide a specific and more elementary approach to modeling crystal size distributions, as well as the modeling the kinetics of crystal nucleation and growth rates. Other chapters discuss a wide range of system analysis and design considerations specific to crystallization for both the steady state and unsteady state. The final chapters illustrate the use of a population balance analysis to interpret data from both laboratory and process equipment. These chapters also explore a wide variety of particulate processes and systems for which the population balance analysis is useful. This book is of great value to graduate students with particulate systems course.
Author | : Doraiswami Ramkrishna |
Publisher | : Elsevier |
Total Pages | : 373 |
Release | : 2000-08-08 |
Genre | : Science |
ISBN | : 0080539246 |
Engineers encounter particles in a variety of systems. The particles are either naturally present or engineered into these systems. In either case these particles often significantly affect the behavior of such systems. This book provides a framework for analyzing these dispersed phase systems and describes how to synthesize the behavior of the population particles and their environment from the behavior of single particles in their local environments. Population balances are of key relevance to a very diverse group of scientists, including astrophysicists, high-energy physicists, geophysicists, colloid chemists, biophysicists, materials scientists, chemical engineers, and meteorologists. Chemical engineers have put population balances to most use, with applications in the areas of crystallization; gas-liquid, liquid-liquid, and solid-liquid dispersions; liquid membrane systems; fluidized bed reactors; aerosol reactors; and microbial cultures. Ramkrishna provides a clear and general treatment of population balances with emphasis on their wide range of applicability. New insight into population balance models incorporating random particle growth, dynamic morphological structure, and complex multivariate formulations with a clear exposition of their mathematical derivation is presented. Population Balances provides the only available treatment of the solution of inverse problems essential for identification of population balance models for breakage and aggregation processes, particle nucleation, growth processes, and more. This book is especially useful for process engineers interested in the simulation and control of particulate systems. Additionally, comprehensive treatment of the stochastic formulation of small systems provides for the modeling of stochastic systems with promising new areas of applications such as the design of sterilization systems and radiation treatment of cancerous tumors. - A clear and general treatment of population balances with emphasis on their wide range of applicability. Thus all processes involving solid-fluid and liquid-liquid dispersions, biological populations, etc. are encompassed - Provides new insight into population balance models incorporating random particle growth, dynamic morphological structure, and complex multivariate formulations with a clear exposition of their mathematical derivation - Presents a wide range of solution techniques, Monte Carlo simulation methods with a lucid exposition of their origin and scope for enhancing computational efficiency - An account of self-similar solutions of population balance equations and their significance to the treatment of data on particulate systems - The only available treatment of the solution of inverse problems essential for identification of population balance models for breakage and aggregation processes, particle nucleation and growth processes and so on - A comprehensive treatment of the stochastic formulation of small systems with several new applications
Author | : Alan Randolph |
Publisher | : Elsevier |
Total Pages | : 268 |
Release | : 2012-12-02 |
Genre | : Technology & Engineering |
ISBN | : 0323158498 |
Theory of Particulate Processes: Analysis and Techniques of Continuous Crystallization describes the complexity of crystal size distribution (CSD), secondary nucleation, and growth mechanisms. This book is divided into 10 chapters that present a generalization from CSD studies as a unified predictive theory of particulate systems. After an introduction to CSD and particle-size distribution systems, this book goes on examining several empirical, one-dimensional distribution functions suitable for the latter system. The next chapter presents a unified theory for multidimensional particle distributions which can be used to analyze and predict such distributions in certain regular, well-defined processes. These topics are followed by a survey on how the size distribution of the product of a continuous mixed-suspension, mixed product-removal crystallizer is obtained. Other chapters describe special cases, which apparently obtain in real systems, including effects of classification, poor mixing, crystal breakage, staging, and size-dependent growth. The remaining chapters deal with the ramification of secondary nucleation as contrasted with homogeneous nucleation. This book is of great value to graduate students with particulate systems course.
Author | : Enrique Ortega-Rivas |
Publisher | : CRC Press |
Total Pages | : 494 |
Release | : 2016-04-19 |
Genre | : Science |
ISBN | : 1000218872 |
Suitable for practicing engineers and engineers in training, this book covers the most important operations involving particulate solids. Through clear explanations of theoretical principles and practical laboratory exercises, the text provides an understanding of the behavior of powders and pulverized systems. It also helps readers develop skills for operating, optimizing, and innovating particle processing technologies and machinery in order to carry out industrial operations. The author explores common bulk solids processing operations, including milling, agglomeration, fluidization, mixing, and solid-fluid separation.
Author | : Panagiotis D. Christofides |
Publisher | : Springer Science & Business Media |
Total Pages | : 223 |
Release | : 2013-04-17 |
Genre | : Technology & Engineering |
ISBN | : 9401598827 |
Particulate processes are characterized by the co-presence of a contin uous phase and a dispersed (particulate) phase, and are widely used in industry for the manufacturing of many high-value products. Examples include the crystallization of proteins for pharmaceutical applications, the emulsion polymerization reactors for the production of latex, the aerosol synthesis of titania powder used in the production of white pig ments, and the thermal spray processing of nanostructured coatings. It is now well understood that the physico-chemical and mechanical properties of materials made with particulates depend heavily on the characteristics of the corresponding particle size distribution. This fact, together with recent advances in dynamics of infinite-dimensional sys tems and nonlinear control theory, has motivated extensive research on model-based control of particulate processes using population balances to achieve tight control of particle size distributions. This book - the first of its kind - presents general methods for the synthesis of nonlinear, robust and constrained feedback controllers for broad classes of particulate process models and illustrates their applica tions to industrially-important crystallization, aerosol and thermal spray processes. The controllers use a finite number of measurement sensors and control actuators to achieve stabilization of the closed-loop system, output tracking, attenuation of the effect of model uncertainty and han dling of actuator saturation.
Author | : Alison Lewis |
Publisher | : Cambridge University Press |
Total Pages | : 354 |
Release | : 2015-07-02 |
Genre | : Technology & Engineering |
ISBN | : 1316299082 |
Bridging the gap between theory and practice, this text provides the reader with a comprehensive overview of industrial crystallization. Newcomers will learn all of the most important topics in industrial crystallization, from key concepts and basic theory to industrial practices. Topics covered include the characterization of a crystalline product and the basic process design for crystallization, as well as batch crystallization, measurement techniques, and details on precipitation, melt crystallization and polymorphism. Each chapter begins with an introduction explaining the importance of the topic, and is supported by homework problems and worked examples. Real world case studies are also provided, as well as new industry-relevant information, making this is an ideal resource for industry practitioners, students, and researchers in the fields of industrial crystallization, separation processes, particle synthesis, and particle technology.
Author | : Jim Litster |
Publisher | : Cambridge University Press |
Total Pages | : 343 |
Release | : 2016-10-20 |
Genre | : Science |
ISBN | : 1107007372 |
A unique text providing comprehensive coverage of fundamental particle science, processing and technology. Including quantitative tools, real-world case studies and end-of-chapter problems, it is ideal for students in engineering and applied sciences, as well as for practitioners in a range of industries manufacturing particulate products.
Author | : Rolf Hilfiker |
Publisher | : John Wiley & Sons |
Total Pages | : 645 |
Release | : 2019-01-04 |
Genre | : Science |
ISBN | : 3527697853 |
"Polymorphism in the Pharmaceutical Industry - Solid Form and Drug Development" highlights the relevance of polymorphism in modern pharmaceutical chemistry, with a focus on quality by design (QbD) concepts. It covers all important issues by way of case studies, ranging from properties and crystallization, via thermodynamics, analytics and theoretical modelling right up to patent issues. As such, the book underscores the importance of solid-state chemistry within chemical and pharmaceutical development. It emphasizes why solid-state issues are important, the approaches needed to avoid problems and the opportunities offered by solid-state properties. The authors include true polymorphs as well as solvates and hydrates, while providing information on physicochemical properties, crystallization thermodynamics, quantum-mechanical modelling, and up-scaling. Important analytical tools to characterize solid-state forms and to quantify mixtures are summarized, and case studies on solid-state development processes in industry are also provided. Written by acknowledged experts in the field, this is a high-quality reference for researchers, project managers and quality assurance managers in pharmaceutical, agrochemical and fine chemical companies as well as for academics and newcomers to organic solid-state chemistry.
Author | : Pierre Gy |
Publisher | : Elsevier Science & Technology |
Total Pages | : 464 |
Release | : 1979 |
Genre | : Bulk solids |
ISBN | : |
Author | : Ali Hassanpour |
Publisher | : Royal Society of Chemistry |
Total Pages | : 238 |
Release | : 2019-07-12 |
Genre | : Technology & Engineering |
ISBN | : 1788018478 |
Powder flow has attracted increased attention in recent years as novel formulated and functional products are being developed in powder forms, particularly in pharmaceutical and high value additive manufacturing industries. This book meets a need for a truly integrated modern treatment of dry powder flow, covering theory, robust characterisation techniques, modelling tools and applications. Written by leaders in the field, the book opens by introducing the wide range of powder processing problems faced by industry, the complexities of powders and the myriad of ways their flow behaviour can be characterised. The authors then move on, with contributions from experts, to describe fundamental properties that can be measured, defining the states of stress and shear rate and the considerations that need to be taken account. By providing a comprehensive treatment of all available characterisation techniques, as well as various modelling tools, the reader obtains a clear, practical overview. Case studies and applications connect theory to practical examples across a broad range of industries. This book stands out by not only providing the reader with guidance on what to measure but also how to interpret results, ensuring this is an invaluable text for anyone working on powder flow in the chemical, pharmaceutical and manufacturing industries, as well as students and researchers across chemical and process engineering disciplines.