Theory of Cortical Plasticity

Theory of Cortical Plasticity
Author: Leon N. Cooper
Publisher: World Scientific
Total Pages: 336
Release: 2004
Genre: Science
ISBN: 9789812387912

This invaluable book presents a theory of cortical plasticity and shows how this theory leads to experiments that test both its assumptions and consequences. It elucidates, in a manner that is accessible to students as well as researchers, the role which the BCM theory has played in guiding research and suggesting experiments that have led to our present understanding of the mechanisms underlying cortical plasticity. Most of the connections between theory and experiment that are discussed require complex simulations. A unique feature of the book is the accompanying software package, Plasticity. This is provided complete with source code, and enables the reader to repeat any of the simulations quoted in the book as well as to vary either parameters or assumptions. Plasticity is thus a research and an educational tool. Readers can use it to obtain hands-on knowledge of the structure of BCM and various other learning algorithms. They can check and replicate our results as well as test algorithms andrefinements of their own.

How We Learn, how We Remember

How We Learn, how We Remember
Author: Leon N. Cooper
Publisher: World Scientific
Total Pages: 416
Release: 1995
Genre: Medical
ISBN: 9789810218157

Leon Cooper's somewhat peripatetic career has resulted in work in quantum field theory, superconductivity, the quantum theory of measurement as well as the mechanisms that underly learning and memory. He has written numerous essays on a variety of subjects as well as a highly regarded introduction to the ideas and methods of physics for non-physicists. Among the many accolades, he has received (some deserved) one he likes specially is the comment of an anonymous reviewer who characterized him as ?a nonsense physicist?.This compilation of papers presents the evolution of his thinking on mechanisms of learning, memory storage and higher brain function. The first half proceeds from early models of memory and synaptic plasticity to a concrete theory that has been put into detailed correspondence with experiment and leads to the very current exploration of the molecular basis for learning and memory storage. The second half outlines his efforts to investigate the properties of neural network systems and to explore to what extent they can be applied to real world problems.In all this collection, hopefully, provides a coherent, no-nonsense, account of a line of research that leads to present investigations into the biological basis for learning and memory storage and the information processing and classification properties of neural systems.

Cognitive Plasticity in Neurologic Disorders

Cognitive Plasticity in Neurologic Disorders
Author: Joseph I. Tracy
Publisher: Oxford University Press, USA
Total Pages: 433
Release: 2014-12-02
Genre: Medical
ISBN: 0199965242

This volume makes clear that the cognitive and behavioural symptoms of neurologic disorders and syndromes are dynamic and changing. Each chapter describes the neuroplastic processes at work in a particular condition, giving rise to these ongoing cognitive changes.

Translational Research in Traumatic Brain Injury

Translational Research in Traumatic Brain Injury
Author: Daniel Laskowitz
Publisher: CRC Press
Total Pages: 388
Release: 2016-04-21
Genre: Medical
ISBN: 1498766579

Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme

Brain Plasticity and Behavior

Brain Plasticity and Behavior
Author: Bryan Kolb
Publisher: Psychology Press
Total Pages: 226
Release: 1995
Genre: Brain
ISBN: 9780805815207

First Published in 1995. Routledge is an imprint of Taylor & Francis, an informa company.

The Neuroscience of Adolescence

The Neuroscience of Adolescence
Author: Adriana Galván
Publisher: Cambridge University Press
Total Pages: 341
Release: 2017-07-10
Genre: Medical
ISBN: 1107089921

Written by an award-winning developmental neuroscientist, this is a comprehensive and cutting-edge account of the latest research on the adolescent brain.

Neuronal Plasticity: Building a Bridge from the Laboratory to the Clinic

Neuronal Plasticity: Building a Bridge from the Laboratory to the Clinic
Author: Jordan Grafman
Publisher: Springer Science & Business Media
Total Pages: 298
Release: 2012-12-06
Genre: Medical
ISBN: 3642598978

Over the last twenty years there has been an explosive growth in our understanding of the molecular, cellular, and anatomical changes that occur in the days and weeks following brain injury. It is now clear that training and exposure to certain environments can modify and shape neuronal plasticity in lower animals and humans. In humans, in particular, there are new ways of charting neuronal plasticity at the ensemble or regional level using functional neuroimaging techniques such as positron emission tomography and functional magnetic resonance imaging. Thus, the time seems right for transporting the laboratory results to the clinic so that experimental findings can be tested in the "field". This volume provides some impetus to moving the field of cognitive neuroscience a little further in its efforts to improve the lives of patients who have suffered a debilitating brain injury.

The Cambridge Handbook of Successful Aging

The Cambridge Handbook of Successful Aging
Author: Rocío Fernández-Ballesteros
Publisher: Cambridge University Press
Total Pages: 969
Release: 2019-01-24
Genre: Psychology
ISBN: 1108641431

Recent studies show that more people than ever before are reaching old age in better health and enjoying that health for a longer time. This Handbook outlines the latest discoveries in the study of aging from bio-medicine, psychology, and socio-demography. It treats the study of aging as a multidisciplinary scientific subject, since it requires the interplay of broad disciplines, while offering high motivation, positive attitudes, and behaviors for aging well, and lifestyle changes that will help people to stay healthier across life span and in old age. Written by leading scholars from various academic disciplines, the chapters delve into the most topical aspects of aging today - including biological mechanisms of aging, aging with health, active and productive aging, aging with satisfaction, aging with respect, and aging with dignity. Aimed at health professionals as well as general readers, this Cambridge Handbook offers a new, positive approach to later life.

The Rewiring Brain

The Rewiring Brain
Author: Arjen van Ooyen
Publisher: Academic Press
Total Pages: 586
Release: 2017-06-23
Genre: Science
ISBN: 0128038721

The adult brain is not as hard-wired as traditionally thought. By modifying their small- or large-scale morphology, neurons can make new synaptic connections or break existing ones (structural plasticity). Structural changes accompany memory formation and learning, and are induced by neurogenesis, neurodegeneration and brain injury such as stroke. Exploring the role of structural plasticity in the brain can be greatly assisted by mathematical and computational models, as they enable us to bridge the gap between system-level dynamics and lower level cellular and molecular processes. However, most traditional neural network models have fixed neuronal morphologies and a static connectivity pattern, with plasticity merely arising from changes in the strength of existing synapses (synaptic plasticity). In The Rewiring Brain, the editors bring together for the first time contemporary modeling studies that investigate the implications of structural plasticity for brain function and pathology. Starting with an experimental background on structural plasticity in the adult brain, the book covers computational studies on homeostatic structural plasticity, the impact of structural plasticity on cognition and cortical connectivity, the interaction between synaptic and structural plasticity, neurogenesis-related structural plasticity, and structural plasticity in neurological disorders. Structural plasticity adds a whole new dimension to brain plasticity, and The Rewiring Brain shows how computational approaches may help to gain a better understanding of the full adaptive potential of the adult brain. The book is written for both computational and experimental neuroscientists. Reviews the current state of knowledge of structural plasticity in the adult brain Gives a comprehensive overview of computational studies on structural plasticity Provides insights into the potential driving forces of structural plasticity and the functional implications of structural plasticity for learning and memory Serves as inspiration for developing novel treatment strategies for stimulating functional repair after brain damage

Synaptic Plasticity

Synaptic Plasticity
Author: Michael R. Kreutz
Publisher: Springer Science & Business Media
Total Pages: 611
Release: 2012-02-18
Genre: Medical
ISBN: 3709109310

This book introduces the current concepts of molecular mechanisms in synaptic plasticity and provides a comprehensive overview of cutting-edge research technology used to investigate the molecular dynamics of the synapses. It explores current concepts on activity-dependent remodeling of the synaptic cytoskeleton and presents the latest ideas on the different forms of plasticity in synapses and dendrites. Synaptic Plasticity in Health and Disease not only supplies readers with extensive knowledge on the latest developments in research, but also with important information on clinical and applied aspects. Changes in spine synapses in different brain disease states, so-called synaptopathies, are explained and described by experts in the field. By outlining basic research findings as well as physiological and pathophysiological impacts on synaptic plasticity, the book represents an essential state-of-the-art work for scientists in the fields of biochemistry, molecular biology and the neurosciences, as well as for doctors in neurology and psychiatry alike.